Found 373 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query ec: 3.4.23.46

Total Genus Sequence Length pdb Title
97 390 6jt3A Crystal structure of bace1 in complex with n-{3-[(4r,5r,6r)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide
0 7 1py1E Complex of gga1-vhs domain and beta-secretase c-terminal phosphopeptide
102 390 6dmiA A multiconformer ligand model of 5t5 bound to bace-1
89 389 3uqrA Crystal structure of bace1 with its inhibitor
95 390 3uquA Crystal structure of bace1 with its inhibitor
96 389 3uqpA Crystal structure of bace1 with its inhibitor
96 388 3u6aA Rational design and synthesis of aminopiperazinones as beta secretase (bace) inhibitors
96 391 3uqxA Crystal structure of bace1 with its inhibitor
92 390 5mxdA Bace-1 in complex with ligand 32397778
103 393 5mcoA Crystal structure of bace-1 in complex with active site inhibitor grl-8234 and exosite peptide
101 393 5mcqA Crystal structure of bace-1 in complex with active site and exosite binding peptide inhibitor
101 390 5mbwA Crystal structure of bace-1 in complex with pep#3
90 387 5kr8A (4~{s},6~{s})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to bace1
90 387 5ie1A Crystal structure of bace1 in complex with 3-(2-amino-6-(o-tolyl)quinolin-3-yl)-n-(3,3-dimethylbutyl)propanamide
100 389 5i3xA Crystal structure of bace1 in complex with aminoquinoline inhibitor 6
92 388 5i3wA Crystal structure of bace1 in complex with 2-aminooxazoline-3-azaxanthene inhibitor 2
94 387 5i3yA Crystal structure of bace1 in complex with aminoquinoline inhibitor 9
104 390 5hu0A Bace1 in complex with 4-(3-(furan-2-carboxamido)phenyl)-1-methyl-5-oxo-4-phenylimidazolidin-2-iminium
107 391 5htzA Bace1 in complex with (s)-5-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-2,5-dimethyl-1,2,4-thiadiazinan-3-iminium 1,1-dioxide
102 391 5hu1A Bace1 in complex with (r)-n-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide
102 390 5ezxA Crystal structure of bace-1 in complex with {(1r,2r)-2-[(r)-2-amino-4-(4-difluoromethoxy-phenyl)-4,5-dihydro-oxazol-4-yl]-cyclopropyl}-(5-chloro-pyridin-3-yl)-methanone
105 390 6fgyA Crystal structure of human bace-1 in complex with amino-1,4-oxazine compound 4
103 388 6eqmA Crystal structure of human bace-1 in complex with cnp520
99 409 6ej2A Bace1 compound 28
95 387 6ej3A Bace1 compound 23
100 389 6dhcA X-ray structure of bace1 in complex with a bicyclic isoxazoline carboxamide as the p3 ligand
95 388 6c2iA Structure of bace-1 (beta-secretase) in complex with : n-(3-((1r,5s,6r)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
106 393 6bfdA Bace crystal structure with hydroxy pyrrolidine inhibitor
105 389 6bfxA Bace crystal structure with hydroxy pyrrolidine inhibitor
105 393 6bfwA Bace crystal structure with hydroxy morpholine inhibitor
106 393 6bfeA Bace crystal structure with hydroxy pyrrolidine inhibitor
98 392 5ygyA Crystal structure of bace1 in complex with (s)-n-(3-(2-amino-6-(fluoromethyl)-4 -methyl-4h-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide
98 389 5ygxA Structure of bace1 in complex with n-(3-((4r,5r,6s)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4h-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide
99 387 5uyuA Crystal structure of bace1 in complex with 2-aminooxazoline-3-azaxanthene compound 12
99 386 4exgA Design and synthesis of potent hydroxyethylamine (hea) bace-1 inhibitors
99 386 4ewoA Design and synthesis of potent hydroxyethylamine (hea) bace-1 inhibitors
97 387 4dpiA Bace-1 in complex with hea-macrocyclic inhibitor, mv078512
94 388 4dvfA Crystal structure of bace1 with its inhibitor
99 387 4dpfA Bace-1 in complex with a hea-macrocyclic type inhibitor
91 387 4dusA Structure of bace-1 (beta-secretase) in complex with n-((2s,3r)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide
94 391 4dv9A Crystal structure of bace1 with its inhibitor
100 391 4di2A Crystal structure of bace1 in complex with hydroxyethylamine inhibitor 37
99 388 4d8cA Crystal structure of human beta secretase in complex with nvp-bxd552, derived from a co-crystallization experiment
104 390 4djyA Structure of bace bound to (r)-5-cyclopropyl-2-imino-3-methyl-5-(3-(5-(prop-1-yn-1-yl)pyridin-3-yl)phenyl)imidazolidin-4-one
95 388 4d83A Crystal structure of human beta secretase in complex with nvp-bur436, derived from a co-crystallization experiment
90 387 4dh6A Structure of bace-1 (beta-secretase) in complex with (2r)-n-((2s,3r)-1-(benzo[d][1,3]dioxol-5-yl)-3-hydroxy-4-((s)-6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridine]-4'-ylamino)butan-2-yl)-2-methoxypropanamide
104 390 4djxA Structure of bace bound to 5-(3-(5-chloropyridin-3-yl)phenyl)-5-cyclopropyl-2-imino-3-methylimidazolidin-4-one
106 390 4djvA Structure of bace bound to 2-imino-5-(3'-methoxy-[1,1'-biphenyl]-3-yl)-3-methyl-5-phenylimidazolidin-4-one
101 389 4d85A Crystal structure of human beta secretase in complex with nvp-bvi151
105 390 4djuA Structure of bace bound to 2-imino-3-methyl-5,5-diphenylimidazolidin-4-one