|
98
|
388
|
6pz4A |
Co-crystal structure of bace with inhibitor am-6494 |
|
97
|
390
|
7f1dA |
Crystal structure of bace1 in complex with n-{3-[(4r,5r,6r)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-2h,3h-[1,4]dioxino[2,3-c]pyridine-7-carboxamide |
|
102
|
391
|
7n66A |
Bace-1 in complex with ligand 12 |
|
102
|
390
|
7myuA |
Bace-1 in complex with compound #22 |
|
110
|
391
|
7myiA |
Bace-1 in complex with compound #6 |
|
107
|
391
|
7myrA |
Bace-1 in complex with compound #18 |
|
97
|
390
|
7d36A |
Crystal structure of bace1 in complex with n-{3-[(3s)-1-amino-5-fluoro-3-methyl-3,4-dihydro-2,6-naphthyridin-3-yl]-4-fluorophenyl}-5-cyano-3-methylpyridine-2-carboxamide |
|
97
|
389
|
7b1qA |
Crystal structure of human bace-1 in complex with compound nb-360 (compound 54) |
|
102
|
388
|
7b1pA |
Crystal structure of human bace-1 in complex with compound 38a (nb-854) |
|
96
|
388
|
7b1eA |
Bace1 in complex with compound 3 (nb-641) |
|
97
|
391
|
7d2vA |
Crystal structure of bace1 in complex with n-{3-[(5r)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2h-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide |
|
94
|
389
|
7d5aA |
Crystal structure of bace1 in complex with n-{3-[(9s)-7-amino-2,2-difluoro-9-(prop-1-yn-1-yl)-6-oxa-8-azaspiro[3.5]non-7-en-9-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide |
|
101
|
389
|
7d2xA |
Crystal structure of bace1 in complex with n-{3-[(4r)-2-amino-4-(prop-1-yn-1-yl)-5,6-dihydro-4h-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide |
|
91
|
390
|
7dczA |
Crystal structure of bace1 in complex with n-{3-[(4s)-2-amino-4-methyl-4h-1,3-thiazin-4-yl]-4- fluorophenyl}-5-cyanopyridine-2-carboxamide |
|
101
|
388
|
5qdaA |
Crystal structure of bace complex with bmc013 |
|
97
|
388
|
5qczA |
Crystal structure of bace complex with bmc015 |
|
101
|
388
|
5qdcA |
Crystal structure of bace complex with bmc019 hydrolyzed |
|
99
|
388
|
5qd7A |
Crystal structure of bace complex with bmc014 |
|
96
|
388
|
5qd1A |
Crystal structure of bace complex with bmc011 |
|
97
|
388
|
5qd9A |
Crystal structure of bace complex with bmc005 |
|
101
|
388
|
5qcpA |
Crystal structure of bace complex with bmc018 |
|
97
|
388
|
5qd6A |
Crystal structure of bace complex with bmc004 |
|
98
|
388
|
5qd4A |
Crystal structure of bace complex with bmc023 |
|
96
|
388
|
5qd8A |
Crystal structure of bace complex with bmc003 |
|
100
|
388
|
5qcwA |
Crystal structure of bace complex with bmc021 |
|
99
|
388
|
5qcsA |
Crystal structure of bace complex with bmc024 |
|
102
|
388
|
5qcvA |
Crystal structure of bace complex with bmc023 |
|
99
|
388
|
5qdbA |
Crystal structure of bace complex with bmc002 |
|
100
|
388
|
5qctA |
Crystal structure of bace complex with bmc001 |
|
98
|
388
|
5qcqA |
Crystal structure of bace complex with bmc025 |
|
98
|
388
|
5qcrA |
Crystal structure of bace complex with bmc026 |
|
98
|
387
|
5qd0A |
Crystal structure of bace complex withbmc006 |
|
102
|
388
|
5qddA |
Crystal structure of bace complex with bmc020 hydrolyzed |
|
97
|
388
|
5qd2A |
Crystal structure of bace complex with bmc017 |
|
98
|
388
|
5qcxA |
Crystal structure of bace complex with bmc007 |
|
96
|
388
|
5qd3A |
Crystal structure of bace complex with bmc010 |
|
97
|
388
|
5qcoA |
Crystal structure of bace complex with bmc016 |
|
102
|
388
|
5qd5A |
Crystal structure of bace complex with bmc009 |
|
101
|
388
|
5qcyA |
Crystal structure of bace complex with bmc008 |
|
101
|
388
|
5qcuA |
Crystal structure of bace complex with bmc022 |
|
99
|
388
|
6wnyA |
Crystal structure of bace1 in complex with (z)-fluoro-olefin containing compound 15 |
|
95
|
389
|
6jt4A |
Crystal structure of bace1 in complex with n-{3-[(4s,6s)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide |
|
106
|
389
|
6uvyA |
Bace-1 in complex with compound #18 |
|
108
|
391
|
6uwvA |
Bace-1 in complex with compound #34 |
|
109
|
393
|
6uwpA |
Bace-1 in complex with compound #32 |
|
107
|
391
|
6uvpA |
Bace-1 in complex with compound #3 |
|
108
|
393
|
6uvvA |
Bace-1 in complex with compound #17 |
|
97
|
390
|
6jt3A |
Crystal structure of bace1 in complex with n-{3-[(4r,5r,6r)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide |
|
97
|
391
|
6od6A |
Structure of bace-1 in complex with ligand 13 |
|
102
|
388
|
6nv9A |
Bace1 in complex with a macrocyclic inhibitor |
