Found 386 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query: beta-secretase 1

Total Genus Sequence Length pdb Title
95 389 6jt4A Crystal structure of bace1 in complex with n-{3-[(4s,6s)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide
106 389 6uvyA Bace-1 in complex with compound #18
108 391 6uwvA Bace-1 in complex with compound #34
109 393 6uwpA Bace-1 in complex with compound #32
108 393 6uvvA Bace-1 in complex with compound #17
107 391 6uvpA Bace-1 in complex with compound #3
97 390 6jt3A Crystal structure of bace1 in complex with n-{3-[(4r,5r,6r)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide
97 391 6od6A Structure of bace-1 in complex with ligand 13
102 388 6nv9A Bace1 in complex with a macrocyclic inhibitor
100 388 6nv7A Bace1 in complex with a macrocyclic inhibitor
104 387 6nw3A Bace1 in complex with a macrocyclic inhibitor
97 390 6e3zA Structure of bace-1 in complex with ligand 8
102 391 6jseA Crystal structure of bace1 in complex with n-(3-((4s,5r)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4h-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide
93 391 6jsgA Crystal structure of bace1 in complex with n-{3-[(4s)-2-amino-4-methyl-5,6-dihydro-4h-1,3-thiazin-4-yl]-4-fluorophenyl}-5-chloropyridine-2-carboxamide
99 391 6jsnA Crystal structure of bace1 in complex with n-{3-[(5r)-3-amino-5-methyl-9,9-dioxo-2,9lambda6-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide
99 392 6jsfA Crystal structure of bace1 in complex with n-(3-((4s,5s)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4h-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide
0 20 5mcqD Crystal structure of bace-1 in complex with active site and exosite binding peptide inhibitor
0 7 2zhrD Crystal structure of bace1 in complex with om99-2 at ph 5.0
0 14 1xn3I Crystal structure of beta-secretase bound to a long inhibitor with additional upstream residues.
0 10 1xn2E New substrate binding pockets for beta-secretase.
102 390 6dmiA A multiconformer ligand model of 5t5 bound to bace-1
96 388 3u6aA Rational design and synthesis of aminopiperazinones as beta secretase (bace) inhibitors
96 391 3uqxA Crystal structure of bace1 with its inhibitor
95 390 3uquA Crystal structure of bace1 with its inhibitor
96 389 3uqpA Crystal structure of bace1 with its inhibitor
89 389 3uqrA Crystal structure of bace1 with its inhibitor
92 390 5mxdA Bace-1 in complex with ligand 32397778
101 393 5mcqA Crystal structure of bace-1 in complex with active site and exosite binding peptide inhibitor
103 393 5mcoA Crystal structure of bace-1 in complex with active site inhibitor grl-8234 and exosite peptide
101 390 5mbwA Crystal structure of bace-1 in complex with pep#3
90 387 5kr8A (4~{s},6~{s})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to bace1
90 387 5ie1A Crystal structure of bace1 in complex with 3-(2-amino-6-(o-tolyl)quinolin-3-yl)-n-(3,3-dimethylbutyl)propanamide
100 389 5i3xA Crystal structure of bace1 in complex with aminoquinoline inhibitor 6
94 387 5i3yA Crystal structure of bace1 in complex with aminoquinoline inhibitor 9
92 388 5i3wA Crystal structure of bace1 in complex with 2-aminooxazoline-3-azaxanthene inhibitor 2
107 391 5htzA Bace1 in complex with (s)-5-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-2,5-dimethyl-1,2,4-thiadiazinan-3-iminium 1,1-dioxide
104 390 5hu0A Bace1 in complex with 4-(3-(furan-2-carboxamido)phenyl)-1-methyl-5-oxo-4-phenylimidazolidin-2-iminium
102 391 5hu1A Bace1 in complex with (r)-n-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide
102 390 5ezxA Crystal structure of bace-1 in complex with {(1r,2r)-2-[(r)-2-amino-4-(4-difluoromethoxy-phenyl)-4,5-dihydro-oxazol-4-yl]-cyclopropyl}-(5-chloro-pyridin-3-yl)-methanone
105 390 6fgyA Crystal structure of human bace-1 in complex with amino-1,4-oxazine compound 4
103 388 6eqmA Crystal structure of human bace-1 in complex with cnp520
95 387 6ej3A Bace1 compound 23
99 409 6ej2A Bace1 compound 28
100 389 6dhcA X-ray structure of bace1 in complex with a bicyclic isoxazoline carboxamide as the p3 ligand
95 388 6c2iA Structure of bace-1 (beta-secretase) in complex with : n-(3-((1r,5s,6r)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
106 393 6bfdA Bace crystal structure with hydroxy pyrrolidine inhibitor
105 393 6bfwA Bace crystal structure with hydroxy morpholine inhibitor
106 393 6bfeA Bace crystal structure with hydroxy pyrrolidine inhibitor
105 389 6bfxA Bace crystal structure with hydroxy pyrrolidine inhibitor
98 389 5ygxA Structure of bace1 in complex with n-(3-((4r,5r,6s)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4h-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide