|
53
|
186
|
8wgnA |
Human dihydrofolate reductase (hsdhfr) complexed with nadph and la1 |
|
46
|
159
|
9kz4A |
Dihydrofolate reductase binding to nadph and trimethoprim-tetramethylrhodamine |
|
44
|
164
|
8vtcA |
Crystal structure of mycobacterium avium dihydrofolate reductase in complex with nadph and trimethoprim |
|
41
|
159
|
9pxcA |
Y100f mutant of e. coli dihydrofolate reductase complexed with nadp+ (oxidized form) |
|
47
|
178
|
9oniA |
Crystal structure of dihydrofolate reductase (dhfr) from the filarial nematode w. bancrofti in complex with nadph and methotrexate (mtx) |
|
51
|
181
|
9ooiA |
Crystal structure of dihydrofolate reductase (dhfr) from the filarial nematode w. bancrofti in complex with nadph and antifolate 2-({4-[(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)benzoic acid (og7 or tsd001) |
|
53
|
181
|
9mltA |
Crystal structure of dihydrofolate reductase (dhfr) from the filarial nematode w. bancrofti in complex with nadph and [2-({4-[(2-amino-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-cyanophenyl]acetic acid (tsd25 or ofd) |
|
55
|
180
|
9mlmA |
Crystal structure of dihydrofolate reductase (dhfr) from the filarial nematode w. bancrofti in complex with nadph and [2-({4-[(2-amino-4-oxo-4,7-dihydro-3h-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzene-1-carbonyl}amino)-4-methoxyphenyl]acetic acid (tsd10 or oed) |
|
42
|
159
|
8vz4A |
L54g mutant of e. coli dihydrofolate reductase complexed with nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
40
|
159
|
8cowA |
Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-(cyclopropylethynyl)-6-(2-fluorophenyl)pyrimidine-2,4-diamine |
|
39
|
159
|
8cq8A |
Mycobacterium tuberculosis dihydrofolate reductase in complex with methyl 4-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)benzoate |
|
35
|
159
|
8cqaA |
Mycobacterium tuberculosis dihydrofolate reductase in complex with n-(4-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)acetamide |
|
41
|
159
|
8cq9A |
Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-(cyclopropylethynyl)-6-(4-(trifluoromethyl)phenyl)pyrimidine-2,4-diamine |
|
38
|
159
|
8coxA |
Mycobacterium tuberculosis dihydrofolate reductase in complex with n-(2-(2,6-diamino-5-(cyclopropylethynyl)pyrimidin-4-yl)phenyl)methanesulfonamide |
|
46
|
159
|
8g4zA |
E. coli dhfr complex with nadp+ and folate: ef-x off model by laue diffraction (no electric field) |
|
44
|
159
|
8g50A |
E. coli dhfr complex with nadp+ and folate: ef-x excited state model by laue diffraction (electric field along b axis; 8-fold extrapolation of structure factor differences) |
|
40
|
157
|
6pboX |
Staphylococcus aureus dihydrofolate reductase in complex with nadph and ucp1232 |
|
42
|
157
|
6p9zX |
Staphylococcus aureus dihydrofolate reductase in complex with nadph and methotrexate |
|
41
|
157
|
7t7sX |
R-27 in complex with s. aureus dhfr and tricyclic-nadph (tnadph) |
|
41
|
157
|
7t7qX |
R-27 in complex with s. aureus dhfr and alpha-nadph - remediated for comparison with tnadph |
|
42
|
163
|
8f80A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam738 |
|
42
|
163
|
8f81A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam777 |
|
44
|
164
|
8f83A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam846 |
|
45
|
163
|
8f84A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam787 |
|
45
|
163
|
8f82A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam845 |
|
45
|
163
|
8f85A |
Crystal structure of dihydrofolate reductase (dhfr) from mycobacterium ulcerans agy99 in complex with nadp and inhibitor mam851 |
|
39
|
166
|
5scrA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-735 |
|
41
|
166
|
5scuA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-888 |
|
43
|
173
|
5sctA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-783 |
|
42
|
167
|
5scsA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-781 |
|
42
|
166
|
5scqA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-614 |
|
39
|
166
|
5sd3A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1088 |
|
45
|
166
|
5sczA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1224 |
|
52
|
186
|
5sd9A |
Crystal structure of dihydrofolate reductase from homo sapiens bound to nadp and sddc inhibitor sddc-1096 |
|
41
|
166
|
5sd5A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1230 |
|
44
|
166
|
5sd4A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1218 |
|
43
|
166
|
5scoA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-m7 |
|
54
|
187
|
5sd6A |
Crystal structure of dihydrofolate reductase from homo sapiens bound to nadp and sddc inhibitor sddc-892 |
|
44
|
168
|
5scpA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-23 |
|
54
|
186
|
5sd8A |
Crystal structure of dihydrofolate reductase from homo sapiens bound to nadp and sddc inhibitor sddc-1190 (racemic mixture) |
|
42
|
172
|
5scxA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1190 (racemic mixture) |
|
46
|
173
|
5scvA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-889 |
|
40
|
165
|
5scmA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-22 |
|
40
|
171
|
5sd2A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1236 (enantiomer) |
|
42
|
168
|
5scyA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1198 |
|
44
|
169
|
5sd1A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1235 (enantiomer) |
|
54
|
186
|
5sd7A |
Crystal structure of dihydrofolate reductase from homo sapiens bound to nadp and sddc inhibitor sddc-735 |
|
55
|
186
|
5sdaA |
Crystal structure of dihydrofolate reductase from homo sapiens bound to nadp and sddc inhibitor sddc-774 |
|
42
|
166
|
5sd0A |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-1225 |
|
43
|
167
|
5scnA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-25 |
