|
89
|
244
|
9bpxA |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with (1'-(4-((1-butylpyrrolidin-3-yl)methoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
91
|
240
|
8vv1A |
Estrogen receptor alpha ligand binding domain in complex with palazestrant |
|
95
|
250
|
9b25A |
Crystal structure of the er-alpha ligand-binding domain (l372s, l536s) in complex with na98 |
|
91
|
240
|
9b2bA |
Estrogen receptor alpha ligand binding domain in complex with a complete estrogen receptor antagonists that favors tetramer formation |
|
86
|
241
|
7te7A |
Estrogen receptor alpha ligand binding domain in complex with rad1901 |
|
81
|
241
|
7uj7A |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with ru39411 |
|
86
|
239
|
7ujmA |
Estrogen receptor alpha ligand binding domain in complex with a methylated lasofoxifene derivative that increases receptor resonance time in the nucleus of breast cancer cells |
|
86
|
240
|
7ujyA |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time |
|
86
|
240
|
7ujfA |
Estrogen receptor alpha ligand binding domain in complex with a methylated lasofoxifene derivative with selective estrogen receptor degrader properties |
|
87
|
244
|
7ujcA |
Raloxifene in complex with estrogen receptor alpha ligand binding domain y537s mutation |
|
78
|
240
|
7ujwA |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with a methylated lasofoxifene derivative that possesses selective estrogen receptor degrader activities |
|
71
|
240
|
7uj8A |
Estrogen receptor alpha ligand binding domain y537s in complex with 4-hydroxytamoxifen |
|
86
|
238
|
7ujoA |
Estrogen receptor alpha ligand binding domain in complex with ru39411 |
|
1
|
8
|
7t2xC |
Estrogen receptor alpha ligand binding domain y537s in complex with 2-chloro-4-((4-hydroxybenzyl)amino)-5-phenylthieno[2,3-d]pyrimidin-6-ol and grip peptide |
|
70
|
238
|
7t2xA |
Estrogen receptor alpha ligand binding domain y537s in complex with 2-chloro-4-((4-hydroxybenzyl)amino)-5-phenylthieno[2,3-d]pyrimidin-6-ol and grip peptide |
|
92
|
240
|
7rkeA |
Estrogen receptor alpha ligand binding domain y537s in complex with 4-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and grip peptide |
|
1
|
7
|
7rkeC |
Estrogen receptor alpha ligand binding domain y537s in complex with 4-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and grip peptide |
|
91
|
238
|
7r62A |
Estrogen receptor alpha ligand binding domain in complex with a desmethyl ici164,384 derivative |
|
90
|
242
|
7n9oA |
Estrogen receptor alpha ligand binding domain in complex with aliphatic serd s-c10(15) |
|
90
|
243
|
8dukA |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-(2-(methylamino)ethoxy)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
2
|
8
|
7ymkC |
Estrogen receptor alpha ligand binding domain c381s c417s y537s mutant in complex with an covalent selective estrogen receptor degrader 29c and grip peptide |
|
90
|
249
|
7ymkA |
Estrogen receptor alpha ligand binding domain c381s c417s y537s mutant in complex with an covalent selective estrogen receptor degrader 29c and grip peptide |
|
2
|
8
|
7y8fC |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with an inhibitor 30o and grip peptide |
|
2
|
8
|
7y8gC |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with an inhibitor 30a and grip peptide |
|
95
|
247
|
7y8gA |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with an inhibitor 30a and grip peptide |
|
87
|
248
|
7y8fA |
Estrogen receptor alpha ligand binding domain y537s mutant in complex with an inhibitor 30o and grip peptide |
|
83
|
240
|
7wnvA |
Crystal structure of mutant estrogen receptor alpha y537s in complex with co9 |
|
83
|
250
|
7qvlA |
Oestrogen receptor ligand binding domain in complex with compound 38 |
|
87
|
250
|
7qvjA |
Estrogen receptor alpha in complex with compound 29 |
|
86
|
242
|
8ev1B |
Dual modulators |
|
90
|
243
|
8ev1A |
Dual modulators |
|
1
|
9
|
8ev1C |
Dual modulators |
|
2
|
9
|
8ev2C |
Dual modulators |
|
86
|
244
|
8ev2A |
Dual modulators |
|
90
|
239
|
8dubA |
Estrogen receptor alpha ligand binding domain in complex with ((1'-(4-((1-ethylpyrrolidin-3-yl)methyl)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
82
|
244
|
8dvbA |
Estrogen receptor alpha ligand binding domain in complex with (1'-(4-((1-butylpyrrolidin-3-yl)methoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
86
|
241
|
8dusA |
Estrogen receptor alpha ligand binding domain in complex with (1'-(4-(2-(ethylamino)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
81
|
237
|
8du9A |
Estrogen receptor alpha ligand binding domain in complex with (6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3,4-dihydroisoquinolin-2(1h)-yl)(phenyl)methanone |
|
84
|
238
|
8duiA |
Estrogen receptor alpha ligand binding domain in complex with (1'-(4-(2-(dimethylamino)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
89
|
240
|
8du8A |
Estrogen receptor alpha ligand binding domain in complex with (6-hydroxy-1-(4-((1-propylazetidin-3-yl)oxy)phenyl)-3,4-dihydroisoquinolin-2(1h)-yl)(phenyl)methanone |
|
83
|
239
|
8dudA |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-(2-(1-propylpyrrolidin-3-yl)ethoxy)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
83
|
241
|
8dv8A |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-((2-(1-propylpyrrolidin-3-yl)ethyl)thio)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
88
|
243
|
8dv7A |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-(2-(1-propylpyrrolidin-3-yl)ethyl)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
86
|
236
|
8duhA |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-(2-((r)-2-methylpyrrolidin-1-yl)ethoxy)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
88
|
240
|
8du6A |
Estrogen receptor alpha ligand binding domain in complex with (1'-(4-((1-ethylazetidin-3-yl)oxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
81
|
237
|
8dugA |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-(2-((s)-3-methylpyrrolidin-1-yl)ethoxy)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
87
|
239
|
8dv5A |
Estrogen receptor alpha ligand binding domain in complex with (6'-hydroxy-1'-(4-((1-pentylpyrrolidin-3-yl)methoxy)phenyl)-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
80
|
239
|
8ducA |
Estrogen receptor alpha ligand binding domain in complex with (1'-(4-(2-(1-ethylpyrrolidin-3-yl)ethoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'h-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone |
|
1
|
7
|
7sfoC |
Estrogen receptor alpha ligand binding domain y537s in complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and grip peptide |
|
85
|
240
|
7sfoA |
Estrogen receptor alpha ligand binding domain y537s in complex with 3-(((2-chloro-5-phenylthieno[2,3-d]pyrimidin-4-yl)amino)methyl)phenol and grip peptide |
