|
62
|
170
|
9bi1A |
Crystal structure of gmppnp bound kras g12d in complex with cypa and rmc-7977 |
|
49
|
163
|
9bi1B |
Crystal structure of gmppnp bound kras g12d in complex with cypa and rmc-7977 |
|
65
|
169
|
8wb1A |
Crystal structure of small molecule kn2h covalently bound to k-ras(g12d) |
|
56
|
167
|
8vgqA |
Cryoem structure of gne-1952-alkylated kras g12c in complex with engineered conformationally rigid fab 2h11.4ds |
|
41
|
214
|
8vgqL |
Cryoem structure of gne-1952-alkylated kras g12c in complex with engineered conformationally rigid fab 2h11.4ds |
|
36
|
224
|
8vgqH |
Cryoem structure of gne-1952-alkylated kras g12c in complex with engineered conformationally rigid fab 2h11.4ds |
|
59
|
167
|
8r7xA |
Kras g12d in complex with compound 4 |
|
59
|
167
|
8r7wA |
Kras g12d in complex with compound 3 |
|
65
|
169
|
8v3aA |
Crystal structure of kras-g12c (gdp-bound) in complex with bbo-8520 |
|
64
|
169
|
8v39A |
Crystal structure of active kras-g12c (gmppnp-bound) in complex with bbo-8520 |
|
65
|
167
|
9o0rA |
Crystal structure of wild-type kras (gdp-bound) in complex with mrtx849 (adagrasib) |
|
57
|
168
|
9o0sA |
Crystal structure of kras-q61r mutant, gmppnp-bound |
|
58
|
168
|
9iayA |
Structure of 10 in complex with gdp-kras |
|
54
|
168
|
9ib5A |
Structure of 18 (bi-2493) in complex with gdp-kras |
|
58
|
168
|
9iapA |
Structure of 1 in complex with gdp-kras |
|
57
|
168
|
9ib4A |
Structure of 12 in complex with gdp-kras |
|
56
|
168
|
9iawA |
Structure of 5 in complex with gdp-kras |
|
54
|
164
|
9ax6C |
Tricomplex of rmc-6236, kras g12d, and cypa |
|
57
|
168
|
9ax6A |
Tricomplex of rmc-6236, kras g12d, and cypa |
|
65
|
170
|
8t4vA |
Crystal structure of compound 1 bound to k-ras(g12d) |
|
21
|
132
|
8t75B |
Crystal structure of kras4a (gmppnp) in complex with raf1 (rbd-crd) |
|
16
|
76
|
8t74B |
Crystal structure of kras4a (gmppnp) in complex with raf1 (rbd) |
|
63
|
168
|
8t73A |
Crystal structure of kras4a-r151g with bound gdp and mg ion |
|
52
|
170
|
8t75A |
Crystal structure of kras4a (gmppnp) in complex with raf1 (rbd-crd) |
|
58
|
170
|
8t71B |
Crystal structure of wt kras4a with bound gdp and mg ion |
|
58
|
170
|
8t74A |
Crystal structure of kras4a (gmppnp) in complex with raf1 (rbd) |
|
54
|
169
|
8t72A |
Crystal structure of wt kras4a with bound gmppnp and mg ion |
|
63
|
171
|
8t71A |
Crystal structure of wt kras4a with bound gdp and mg ion |
|
59
|
169
|
8tbnA |
Tricomplex of rmc-7977, kras g12s, and cypa |
|
51
|
164
|
8tbkC |
Tricomplex of rmc-7977, kras g12c, and cypa |
|
53
|
165
|
8tbnC |
Tricomplex of rmc-7977, kras g12s, and cypa |
|
54
|
165
|
8tbmC |
Tricomplex of rmc-7977, kras g12v, and cypa |
|
53
|
165
|
8tbfC |
Tricomplex of rmc-7977, kras wt, and cypa |
|
52
|
163
|
8tbhC |
Tricomplex of rmc-7977, kras g12r, and cypa |
|
60
|
170
|
8tbjA |
Tricomplex of rmc-7977, kras g12a, and cypa |
|
55
|
165
|
8tbjC |
Tricomplex of rmc-7977, kras g12a, and cypa |
|
62
|
170
|
8tbkA |
Tricomplex of rmc-7977, kras g12c, and cypa |
|
61
|
168
|
8tblA |
Tricomplex of rmc-7977, kras g12d, and cypa |
|
60
|
170
|
8tbhA |
Tricomplex of rmc-7977, kras g12r, and cypa |
|
60
|
170
|
8tbfA |
Tricomplex of rmc-7977, kras wt, and cypa |
|
52
|
165
|
8tblC |
Tricomplex of rmc-7977, kras g12d, and cypa |
|
60
|
168
|
8tbmA |
Tricomplex of rmc-7977, kras g12v, and cypa |
|
67
|
169
|
8jgdA |
Gdp-bound kras g12c in complex with yk-8s |
|
61
|
168
|
8un3A |
Kras-g13d-gdp in complex with cpd5 (1-((s)-10-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-11-chloro-7-(((2s,4r)-4-fluoro-1-methylpyrrolidin-2-yl)methoxy)-3,4,13,13a-tetrahydropyrazino[2',1':3,4][1,4]oxazepino[5,6,7-de]quinazolin-2(1h)-yl)prop-2-en-1-one) |
|
62
|
170
|
8un4A |
Kras-g13d-gdp in complex with cpd36 ((e)-1-((3s)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((s)-2-methylenetetrahydro-1h-pyrrolizin-7a(5h)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(4-((dimethylamino)methyl)-5-methylpyridin-2-yl)prop-2-en-1-one) |
|
65
|
169
|
8un5A |
Kras-g13d-gdp in complex with cpd38 ((e)-1-((3s)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((s)-2-methylenetetrahydro-1h-pyrrolizin-7a(5h)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one) |
|
68
|
169
|
7t47A |
Kras g12d (gppcp) with mrtx-1133 |
|
57
|
170
|
7rp2A |
Crystal structure of kas g12c in complex with 2h11 clamp |
|
43
|
215
|
7rp2I |
Crystal structure of kas g12c in complex with 2h11 clamp |
|
64
|
183
|
7q9uAAA |
Crystal structure of the high affinity kras mutant pde6d complex |
