|
67
|
209
|
7d24A |
Hsp90 alpha n-terminal domain in complex with a 4b compund |
|
69
|
209
|
7d1vA |
Hsp90 alpha n-terminal domain in complex with a 6c compund |
|
65
|
209
|
7d22A |
Hsp90 alpha n-terminal domain in complex with a 6b compund |
|
65
|
209
|
7d25A |
Hsp90 alpha n-terminal domain in complex with a 14 compund |
|
66
|
209
|
7d26A |
Hsp90 alpha n-terminal domain in complex with a 8 compund |
|
69
|
208
|
7lszA |
Hsp90a n-terminal inhibitor |
|
69
|
208
|
7lt0A |
Hsp90a n-terminal inhibitor |
|
69
|
211
|
6lr9A |
Hsp90 in complex with debio0932 |
|
70
|
209
|
6ltiA |
Hsp90 in complex with nvp-auy922 |
|
66
|
209
|
6lszA |
Hsp 90 in complex with ganetespib |
|
68
|
211
|
6lt8A |
Hsp90 in complex with kw-2478 |
|
66
|
208
|
6ltkA |
Hsp90 in complex with snx-2112 |
|
60
|
209
|
6tn5AAA |
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures |
|
60
|
210
|
6tn4AAA |
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures |
|
78
|
253
|
6ksqA |
Middle domain of human hsp90 alpha |
|
68
|
208
|
6u99A |
Hsp90a ntd covalently bound to sulfonyl fluoride probe 1 at k58 |
|
68
|
208
|
6u98A |
Hsp90a ntd k58r bound reversibly to sulfonyl fluoride 6 |
|
67
|
208
|
6u9bA |
Hsp90a ntd covalently bound to sulfonyl fluoride 5 at k58 |
|
67
|
208
|
6u9aA |
Hsp90a ntd k58r bound reversibly to sulfonyl fluoride 5 |
|
66
|
208
|
6hhrA |
Hsp90 in complex with 5-(2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione |
|
71
|
210
|
6n8xA |
Hsp90-alpha bound to pu-11-trans |
|
67
|
209
|
6olxA |
Hsp90-alpha s52a bound to pu-11-trans |
|
66
|
210
|
6b9aA |
Hsp90-alpha n-domain bound to npca |
|
68
|
209
|
5od7A |
Hsp90 inhibitor desolvation as a rationale to steer on-rates and impact residence time |
|
62
|
208
|
6fcjA |
Kinetics of hsp90 inhibitors (title to be refined) |
|
71
|
212
|
5zr3A |
Crystal structure of hsp90-alpha n-terminal domain in complex with 4-(3-isopropyl-4-(4-(1-methyl-1h-pyrazol-4-yl)-1h-imidazol-1-yl)-1h-pyrazolo[3,4-b]pyridin-1-yl)-3-methylbenzamide |
|
67
|
210
|
6cygA |
Hsp90-alpha n-domain bound to neoca |
|
66
|
210
|
6cyhA |
Hsp90-alpha n-domain bound to neaca |
|
65
|
208
|
5xrdA |
Crystal structure of the human hsp90-alpha n-domain bound to the hsp90 inhibitor fs7 |
|
66
|
208
|
5j20A |
Hsp90 in complex with 5-[4-(2-fluoro-phenyl)-5-oxo-4,5-dihydro-1h-[1,2,4]triazol-3-yl]-n-furan-2-ylmethyl-2,4-dihydroxy-n-methyl-benzamide |
|
68
|
207
|
4cwpA |
Human hsp90 alpha n-terminal domain in complex with an aminotriazoloquinazoline inhibitor |
|
68
|
209
|
3tuhA |
Crystal structure of the n-terminal domain of an hsp90 in the presence of an the inhibitor ganetespib |
|
65
|
210
|
6b99A |
Hsp90-alpha n-domain bound to neca |
|
63
|
207
|
5lo6A |
Hsp90 with indazole derivative |
|
65
|
207
|
5lo0A |
Hsp90 with indazole derivative |
|
67
|
208
|
5lr1A |
Crystal structure of hsp90 in complex with a003498614a. |
|
70
|
207
|
5lq9A |
Crystal structure of hsp90 in complex with sar200323. |
|
67
|
208
|
5m4hA |
Application of off-rate screening in the identification of novel pan-isoform inhibitors of pyruvate dehydrogenase kinase |
|
66
|
208
|
5m4eA |
Application of off-rate screening in the identification of novel pan-isoform inhibitors of pyruvate dehydrogenase kinase |
|
69
|
207
|
5lrzA |
Crystal structure of hsp90 in complex with a003643501 |
|
69
|
207
|
5lo5A |
Hsp90 with indole derivative |
|
67
|
207
|
5lnzA |
Hsp90 with indazole derivative |
|
69
|
207
|
5lnyA |
Hsp90 with indazole derivative |
|
67
|
208
|
5lrlA |
Crystal structure of hsp90 in complex with a003492875 |
|
67
|
207
|
5lr7A |
Crystal structure of hsp90 in complex with sar567530 |
|
66
|
208
|
5j8uA |
Crystal structure of hsp90-alpha n-domain l107a mutant in complex with 5-(2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one |
|
60
|
208
|
5j82A |
Crystal structure of hsp90-alpha n-domain in complex 5-[4-(2-fluoro-phenyl)-5-oxo-4,5-dihydro-1h-[1,2,4]triazol-3-yl]-2,4-dihydroxy-n-isopropyl-n-methyl-benzenesulfonamide |
|
66
|
208
|
5j9xA |
Hsp90 in complex with n-butyl-5-[4-(2-fluoro-phenyl)-5-oxo-4,5-dihydro-1h-[1,2,4]triazol-3-yl]-2,4-dihydroxy-n-methyl-benzamide |
|
69
|
209
|
5j2xA |
Crystal structure of hsp90-alpha n-domain in complex with 5-(5-bromo-2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one |
|
68
|
208
|
5j6lA |
Crystal structure of hsp90-alpha n-domain in complex with n-butyl-5-[4-(2-fluoro-phenyl)-5-oxo-4,5-dihydro-1h-[1,2,4]triazol-3-yl]-2,4-dihydroxy-n-methyl-benzamide |
