|
128
|
402
|
9js2A |
Complex structure of athppd with inhibitor yh23570 |
|
108
|
280
|
9p0uA |
Structure of pycr1 complexed with the allosteric inhibitor 7-benzamido-4-hydroxynaphthalene-2-sulfonic acid |
|
107
|
276
|
9q46A |
Ternary complex of pycr1 with the allosteric inhibitor 2-[(2,6-dichlorophenyl)amino]pyridine-3-sulfonic acid in two remote sites and the active site, and (s)-(-)-2-hydroxy-3,3-dimethylbutyric acid in the active site |
|
108
|
279
|
9p0sA |
Structure of pycr1 complexed with the allosteric inhibitor 4-hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid |
|
105
|
275
|
9p0vA |
Structure of pycr1 complexed with the allosteric inhibitor 7-benzamido-4-hydroxynaphthalene-2-sulfonic acid in a remote site and nadh and (s)-(-)-2-hydroxy-3,3-dimethylbutyric acid in the active site |
|
103
|
278
|
9q45A |
Quaternary complex of pycr1 with the allosteric inhibitor 1-benzyl-1h-1,3-benzodiazole-2-sulfonic acid in a remote site and nadh and (s)-tetrahydrofuran-2-carboxylic acid in the active site |
|
108
|
274
|
9p0qA |
Structure of pycr1 complexed with the allosteric inhibitor 1-benzyl-1h-1,3-benzodiazole-2-sulfonic acid |
|
103
|
274
|
9p0tA |
Structure of pycr1 complexed with the allosteric inhibitor 4-hydroxy-7-(phenylamino)naphthalene-2-sulfonic acid in a remote site and nadh and (s)-(-)-2-hydroxy-3,3-dimethylbutyric acid in the active site |
|
140
|
366
|
9bkoA |
Dhodh in complex with ligand 26 |
|
137
|
367
|
9bkmA |
Dhodh in complex with ligand 10 |
|
140
|
366
|
9bknA |
Dhodh in complex with ligand 16 |
|
186
|
593
|
8uy2A |
Methylenetetrahydrofolate reductase from chaetomium thermophilum dsm 1495, adomet-bound, inhibited (t) state |
|
141
|
366
|
9dhgA |
Dhodh in complex with compound 5 |
|
142
|
368
|
9dhhA |
Dhodh in complex with compound 8 |
|
146
|
368
|
9dhjA |
Dhodh in complex with compound 15 |
|
141
|
366
|
9dhiA |
Dhodh in complex with compound 7 |
|
66
|
188
|
8u1yA |
E.coli dsba in complex with n-(4-(thiophen-3-yl)benzyl)cyclohexanamine |
|
141
|
468
|
9bv6A |
Crystal structure of human cyp3a4 in complex with sj000388260 |
|
136
|
469
|
9bvbA |
Crystal structure of human cyp3a4 in complex with sjyhj-075 |
|
153
|
469
|
9bv8A |
Crystal structure of human cyp3a4 in complex with sjyhj-114 |
|
140
|
470
|
9bv9A |
Crystal structure of human cyp3a4 in complex with z56791366 |
|
139
|
470
|
9bvcA |
Crystal structure of human cyp3a4 in complex with sjyhj-110 |
|
143
|
470
|
9bvaA |
Crystal structure of human cyp3a4 in complex with sjyhj-106 |
|
161
|
470
|
9bv5A |
Crystal structure of human cyp3a4 in complex with sj000362065 |
|
148
|
470
|
9bv7A |
Crystal structure of human cyp3a4 in complex with sj000310315 |
|
126
|
413
|
9q4xA |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(dimethylamino)ethyl)-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine |
|
128
|
414
|
9q4zA |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(ethyl(methyl)amino)ethyl)-2,3-difluorophenxy)methyl)-4-methylphridin-2-amine |
|
126
|
418
|
9q4wA |
Structure of rat neuronal nitric oxide synthase r349a mutant heme domain bound with 6-((5-(2-(4,4-difluoropiperidin-1-yl)ethyl-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine |
|
119
|
414
|
9q4yA |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((2,3-difluoro-5-(2-(methylamino)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine |
|
128
|
413
|
9q51A |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(diethylamino)ethyl)-2,3-difluorophenxy)methyl)-4-methylpyridin-2-amine |
|
126
|
414
|
9q58A |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(4,4-difluoropiperidin-1-yl)ethyl-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine |
|
122
|
414
|
9q52A |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(azetidin-1-yl)ethyl)-2,3-difluorophenxy)methyl)-4-methylpyridin-2-amine |
|
130
|
414
|
9q53A |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((2,3-difluoro-5-(2-(piperidin-1-yl)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine |
|
122
|
414
|
9q54A |
Structure of human endothelial nitric oxide synthase heme domain bound with 6-((2,3-difluoro-5-(2-(3-fluoroazetidin-1-yl)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine |
|
105
|
255
|
9pflA |
Crystal structure of human 15-pgdh in complex with small molecule compound 1 |
|
137
|
363
|
8vhmA |
Structure of dhodh in complex with fragment 2 |
|
135
|
365
|
8vhlA |
Structure of dhodh in complex with ligand 17 |
|
158
|
464
|
8u0qA |
Co-crystal structure of optimized analog tdi-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series |
|
215
|
671
|
7lafA |
15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor |
|
103
|
315
|
8fh7A |
Crystal structure of aldose reductase (akr1b1) complexed with nadp+ and at-003 |
|
101
|
315
|
8fh5A |
Crystal structure of aldose reductase (akr1b1) complexed with nadp+ and at-001 |
|
104
|
315
|
8fh6A |
Crystal structure of aldose reductase (akr1b1) complexed with nadp+ and two at-001 |
|
107
|
310
|
7l00A |
Crystal structure of c. difficile enoyl-acyl carrier protein reductase (fabk) in complex with an inhibitor |
|
131
|
335
|
7t6hA |
E. coli dihydroorotate dehydrogenase |
|
128
|
335
|
7t5kA |
E. coli dihydroorotate dehydrogenase bound to the inhibitor hqno |
|
128
|
335
|
7t6cA |
E. coli dihydroorotate dehydrogenase bound to the ubiquinone surrogate dcip |
|
125
|
336
|
7t5yA |
E. coli dihydroorotate dehydrogenase bound to the inhibitor hmnq |
|
162
|
462
|
7n3lA |
Co-complex cyp46a1 with 0420 (compound 6) |
|
106
|
357
|
7jm5A |
Crystal structure of kdm4b in complex with qc6352 |
|
39
|
166
|
5scrA |
Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-735 |
