|
102
|
356
|
7s1nA |
N-aromatic-substituted indazole derivatives as brain penetrant and orally bioavailable jnk3 inhibitors |
|
84
|
320
|
7nwkA |
Crystal structure of cdk9-cyclin t1 bound by compound 6 |
|
107
|
339
|
7a5nA |
Structure of dyrk1a in complex with compound 34 |
|
117
|
341
|
7a52A |
Structure of dyrk1a in complex with compound 6 |
|
115
|
335
|
7a51A |
Structure of dyrk1a in complex with compound 5 |
|
91
|
333
|
7a4sA |
Structure of dyrk1a in complex with compound 2 |
|
119
|
346
|
7a5bA |
Structure of dyrk1a in complex with complex 10 |
|
83
|
273
|
7oowA |
Crystal structure of pim1 in complex with arc-1415 |
|
85
|
273
|
7oovA |
Crystal structure of pim1 in complex with arc-1411 |
|
110
|
346
|
7nqqA |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
101
|
345
|
7nr9A |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
114
|
346
|
7nqwA |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
113
|
346
|
7nr8A |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
109
|
347
|
7nr5A |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
109
|
346
|
7nr3A |
Discovery of astx029, a clinical candidate which modulates the phosphorylation and catalytic activity of erk1/2 |
|
117
|
442
|
7nh5A |
Co-crystal structure of akt1 in complex with covalent-allosteric akt inhibitor 6 |
|
54
|
290
|
7nj0B |
Cryoem structure of the human separase-cdk1-cyclin b1-cks1 complex |
|
114
|
441
|
7nh4A |
Co-crystal structure of akt1 in complex with covalent-allosteric akt inhibitor 3 |
|
67
|
276
|
7naaA |
Crystal structure of mycobacterium tuberculosis h37rv pknf kinase domain |
|
82
|
278
|
7n3uA |
Crystal structure of human wee1 kinase domain in complex with zn-c3 |
|
120
|
346
|
7a4oA |
Structure of dyrk1a in complex with ampnp |
|
75
|
295
|
7lvhA |
Crystal structure of ap2 associated kinase 1 isoform 1 complexed with ligand n-[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]-3-(propan-2-yl)piperidine-2-carboxamide |
|
83
|
297
|
7lviA |
Crystal structure of ap2 associated kinase 1 isoform 1 complexed with ligand (2r)-2-amino-n-[3-methoxy-4- (1,3-oxazol-5-yl)phenyl]-4-methylpentanamide |
|
101
|
328
|
7l1xA |
Structure of human ck2 alpha kinase (catalytic subunit) with the inhibitor 108600. |
|
79
|
268
|
7kx6A |
Crystal structure of dclk1-kd in complex with xmd8-85 |
|
69
|
267
|
7kxwA |
Crystal structure of dclk1-kd in complex with dclk1-in-1 |
|
73
|
268
|
7kxwB |
Crystal structure of dclk1-kd in complex with dclk1-in-1 |
|
64
|
288
|
7kx8A |
Crystal structure of dclk1-cter in complex with fmf-03-055-1 |
|
120
|
340
|
7a4rA |
Structure of dyrk1a in complex with compound 1 |
|
79
|
484
|
7jijA |
Atp-bound amp-activated protein kinase |
|
72
|
273
|
7f3gA |
Crystal structure of dclk1 kinase domain in complex with ruxolitinib |
|
91
|
292
|
7cp4A |
Crystal structure of pak4 in complex with inhibitor 55 |
|
72
|
290
|
7cp3A |
Crystal structure of pak4 in complex with inhibitor 47 |
|
140
|
406
|
7bmkA |
Atp-competitive partial antagonists-'pair's-rheostatically modulate ire1alpha's kinase helix-alphac to segregate its rnase-mediated biological outputs |
|
80
|
293
|
7b7sA |
Cdk2/cyclin a2 in complex with 3h-pyrazolo[4,3-f]quinoline-based derivative hsd1368 |
|
113
|
328
|
7atvA |
Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the bivalent inhibitor kn2 |
|
111
|
347
|
7auvA |
The structure of erk2 in complex with dual inhibitor astx029 |
|
108
|
430
|
7apjA |
Structure of autoinhibited akt1 reveals mechanism of pip3-mediated activation |
|
111
|
328
|
7at9A |
Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the atp-competitive inhibitor mb002 and the alphad-pocket ligand 3,4-dichlorophenethylamine |
|
117
|
332
|
7at5A |
Structure of protein kinase ck2 catalytic subunit (csnk2a1 gene product) in complex with the bivalent inhibitor kn2 |
|
117
|
347
|
6ln1A |
A natural inhibitor of dyrk1a for treatment of diabetes mellitus |
|
82
|
320
|
6w9eA |
Crystal structure of human cdk9/cyclint1 in complex with mc180295 |
|
80
|
306
|
7ooxA |
Crystal structure of pim1 in complex with arc-3126 |
|
92
|
316
|
7p1lA |
The mark3 kinase domain bound to aa-cs-1-008 |
|
111
|
357
|
7orfA |
Crystal structure of jnk3 in complex with fmu-001-367 (compound 1) |
|
111
|
359
|
7oreA |
Crystal structure of jnk3 in complex with light-activated covalent inhibitor mr-ii-249 with both non-covalent and covalent binding modes (compound 4) |
|
113
|
337
|
7opgA |
Crystal structure of clk1 in complex with compound 2 (cc513) |
|
64
|
484
|
7jhhA |
Cryo-em structure of atp-bound fully inactive ampk in complex with fab and nanobody |
|
73
|
484
|
7jhgA |
Cryo-em structure of atp-bound fully inactive ampk in complex with dorsomorphin (compound c) and fab-nanobody |
|
88
|
291
|
7cmbA |
Crystal structure of pak4 in complex with inhibitor 41 |
