|
126
|
313
|
5se5A |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[1-methyl-5-(methylcarbamoyl)pyrazol-4-yl]-3-(pyrimidin-5-ylamino)pyrazine-2-carboxamide |
|
130
|
313
|
5sinA |
Crystal structure of human phosphodiesterase 10 in complex with n-(3-methyl-1-pyridin-2-ylthieno[2,3-c]pyrazol-5-yl)benzamide |
|
125
|
312
|
5siyA |
Crystal structure of human phosphodiesterase 10 in complex with 5-[(3r)-3-fluoropyrrolidin-1-yl]-n-methyl-2-(3-methylquinoxalin-2-yl)-n-(oxan-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine |
|
121
|
313
|
5se2A |
Crystal structure of human phosphodiesterase 10 in complex with 2-[2-(1-methyl-4-phenylimidazol-2-yl)ethyl]quinoline |
|
126
|
313
|
5segA |
Crystal structure of human phosphodiesterase 10 in complex with 6-[(5-bromo-1-methyl-2-oxopyridine-3-carbonyl)amino]-n-(oxetan-3-yl)-2-phenyl-3h-benzimidazole-5-carboxamide |
|
126
|
313
|
5si8A |
Crystal structure of human phosphodiesterase 10 in complex with n-(6-cyano-2-phenylimidazo[1,2-a]pyridin-7-yl)-1-methyl-4-(morpholine-4-carbonyl)pyrazole-3-carboxamide |
|
126
|
313
|
5si9A |
Crystal structure of human phosphodiesterase 10 in complex with 4-n-(2-hydroxyethyl)-2-methyl-3-n-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)pyrazole-3,4-dicarboxamide |
|
127
|
313
|
5senA |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-2-methyl-n-(1-quinolin-2-ylimidazol-4-yl)pyrazole-3-carboxamide |
|
125
|
313
|
5sigA |
Crystal structure of human phosphodiesterase 10 in complex with 1-[(4-methoxyphenyl)methyl]-1-[(4-oxo-3h-quinazolin-2-yl)methyl]-3-phenylurea |
|
124
|
314
|
5sjiA |
Crystal structure of human phosphodiesterase 10 in complex with 4-chloro-2-methyl-n-(2-phenyl-1h-benzimidazol-5-yl)pyrazole-3-carboxamide |
|
127
|
313
|
5se7A |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-2-methyl-n-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)pyrazole-3-carboxamide |
|
127
|
313
|
5sgpA |
Crystal structure of human phosphodiesterase 10 in complex with 4-n-(2-methoxyethyl)-4-n,2-dimethyl-3-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3,4-dicarboxamide |
|
126
|
313
|
5sfxA |
Crystal structure of human phosphodiesterase 10 in complex with n-(2-acetamido-1,3-benzothiazol-5-yl)-4-(azetidine-1-carbonyl)-2-methylpyrazole-3-carboxamide |
|
126
|
313
|
5sg0A |
Crystal structure of human phosphodiesterase 10 in complex with 1-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]-3-(2-phenylpyrazol-3-yl)imidazolidin-2-one |
|
127
|
313
|
5sexA |
Crystal structure of human phosphodiesterase 10 in complex with n-methyl-6-[(6-methylpyridine-2-carbonyl)amino]-2-phenyl-3h-benzimidazole-5-carboxamide |
|
125
|
313
|
5sebA |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-3-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethyl]quinoxaline |
|
123
|
312
|
5sfbA |
Crystal structure of human phosphodiesterase 10 in complex with n,2,3-trimethyl-6-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethyl]imidazo[1,2-b]pyridazine-8-carboxamide |
|
123
|
313
|
5sesA |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-2-methyl-n-(2-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide |
|
127
|
313
|
5sevA |
Crystal structure of human phosphodiesterase 10 in complex with 2,3,5-trimethyl-6-[2-(1-methyl-4-phenylimidazol-2-yl)ethyl]pyrazine |
|
125
|
313
|
5sghA |
Crystal structure of human phosphodiesterase 10 in complex with 4-[1-methyl-6-[(1-methyl-4-phenylimidazol-2-yl)methoxy]pyrazolo[3,4-d]pyrimidin-4-yl]morpholine |
|
128
|
314
|
5sefA |
Crystal structure of human phosphodiesterase 10 in complex with 5,7,8-trimethyl-2-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine |
|
122
|
313
|
5shlA |
Crystal structure of human phosphodiesterase 10 in complex with 6-chloro-2,3-dimethyl-8-pyrrolidin-1-ylimidazo[1,2-b]pyridazine |
|
124
|
313
|
5sjkA |
Crystal structure of human phosphodiesterase 10 in complex with 5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one |
|
124
|
313
|
5shnA |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-n-(1,3-oxazol-2-ylmethyl)-3-n-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)pyrazole-3,4-dicarboxamide |
|
123
|
313
|
5sioA |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(2-methylpyrrolidine-1-carbonyl)-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide |
|
126
|
313
|
5sk5A |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(morpholine-4-carbonyl)-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide, space group h3 |
|
124
|
313
|
5sjbA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-3h-imidazo[4,5-f]quinoline |
|
126
|
313
|
5shfA |
Crystal structure of human phosphodiesterase 10 in complex with 3,6-dimethyl-n-(2-phenylpyrazolo[1,5-a]pyridin-6-yl)pyridine-2-carboxamide |
|
126
|
314
|
5simA |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(2-methylpyrrolidine-1-carbonyl)-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide |
|
124
|
313
|
5sjsA |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[4-(dimethylcarbamoyl)pyridin-3-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide |
|
85
|
305
|
7mavA |
Sars-cov-2 main protease (mpro) in complex with covalent inhibitor dffcit-yne |
|
129
|
313
|
5si7A |
Crystal structure of human phosphodiesterase 10 in complex with 2-benzyl-6,6-dimethyl-1h-imidazo[4,5-h]isoquinoline-7,9-dione |
|
122
|
314
|
5sihA |
Crystal structure of human phosphodiesterase 10 in complex with 6-(3-methylphenyl)sulfanyl-2-(4-pyridin-2-ylpiperazin-1-yl)-9h-purine |
|
127
|
313
|
5shqA |
Crystal structure of human phosphodiesterase 10 in complex with 4-pyrrolidin-1-yl-7h-pyrrolo[2,3-d]pyrimidine |
|
122
|
313
|
5shpA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-3h-imidazo[4,5-h]quinoline |
|
130
|
315
|
5shzA |
Crystal structure of human phosphodiesterase 10 in complex with 3-[2-(3-ethynylphenyl)pyrazol-3-yl]-1-phenylpyridazin-4-one |
|
127
|
313
|
5si6A |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-n-(6-cyano-2-phenylimidazo[1,2-a]pyridin-7-yl)-2-methylpyrazole-3-carboxamide |
|
124
|
314
|
5shaA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[2-[5-[3-(difluoromethyl)pyrrolidin-1-yl]-2-methyl-1,2,4-triazol-3-yl]ethyl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine |
|
124
|
313
|
5sh5A |
Crystal structure of human phosphodiesterase 10 in complex with 2-amino-4-cyclohexyloxyquinoline-3-carbonitrile |
|
124
|
313
|
5sgyA |
Crystal structure of human phosphodiesterase 10 in complex with 4-chloro-2-(2-methylpropyl)-n-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)pyrazole-3-carboxamide |
|
127
|
313
|
5sj2A |
Crystal structure of human phosphodiesterase 10 in complex with 2,3-dichloro-n-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)pyridine-4-carboxamide |
|
125
|
313
|
5sjpA |
Crystal structure of human phosphodiesterase 10 in complex with ethyl n-[[4-[[4-(azetidine-1-carbonyl)-2-methylpyrazole-3-carbonyl]amino]-6-methylpyridin-2-yl]carbamothioyl]carbamate |
|
124
|
314
|
5si1A |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(morpholine-4-carbonyl)-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide, space group i23 |
|
121
|
312
|
5sjgA |
Crystal structure of human phosphodiesterase 10 in complex with 1-[2-[2-(5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)ethyl]-1-methylimidazol-4-yl]pyrrolidin-2-one |
|
123
|
313
|
5sf5A |
Crystal structure of human phosphodiesterase 10 in complex with 2,3-dimethyl-6-[2-(1-methyl-4-phenylimidazol-2-yl)ethyl]imidazo[1,2-b]pyridazine |
|
123
|
313
|
5si4A |
Crystal structure of human phosphodiesterase 10 in complex with 3-(2-naphthalen-1-ylpyrazol-3-yl)-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one |
|
123
|
313
|
5siuA |
Crystal structure of human phosphodiesterase 10 in complex with 3-[2-(6,8-dichloro-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)ethyl]-1h-quinoxalin-2-one |
|
82
|
304
|
7matA |
Sars-cov-2 main protease (mpro) in complex with covalent inhibitor dffr |
|
125
|
313
|
5se0A |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[2-(2-hydroxyethyl)-5-pyridin-2-ylpyrazol-3-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide |
|
125
|
314
|
5si3A |
Crystal structure of human phosphodiesterase 10 in complex with 1-methyl-5-[(2-phenylimidazo[1,2-a]pyrimidin-7-yl)carbamoyl]pyrazole-4-carboxylic acid |
