|
122
|
313
|
5shlA |
Crystal structure of human phosphodiesterase 10 in complex with 6-chloro-2,3-dimethyl-8-pyrrolidin-1-ylimidazo[1,2-b]pyridazine |
|
124
|
313
|
5sgyA |
Crystal structure of human phosphodiesterase 10 in complex with 4-chloro-2-(2-methylpropyl)-n-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)pyrazole-3-carboxamide |
|
125
|
314
|
5shyA |
Crystal structure of human phosphodiesterase 10 in complex with [8-[(2-methyl-1,3-thiazol-4-yl)amino]-5-pyridin-3-yl-1,7-naphthyridin-2-yl]methanol |
|
126
|
313
|
5sh6A |
Crystal structure of human phosphodiesterase 10 in complex with 4-[2-(1-methylbenzimidazol-2-yl)ethyl]-2,3-dihydro-1,4-benzoxazepin-5-one |
|
123
|
313
|
5siuA |
Crystal structure of human phosphodiesterase 10 in complex with 3-[2-(6,8-dichloro-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)ethyl]-1h-quinoxalin-2-one |
|
125
|
314
|
5si3A |
Crystal structure of human phosphodiesterase 10 in complex with 1-methyl-5-[(2-phenylimidazo[1,2-a]pyrimidin-7-yl)carbamoyl]pyrazole-4-carboxylic acid |
|
123
|
313
|
5sf5A |
Crystal structure of human phosphodiesterase 10 in complex with 2,3-dimethyl-6-[2-(1-methyl-4-phenylimidazol-2-yl)ethyl]imidazo[1,2-b]pyridazine |
|
124
|
314
|
5si1A |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(morpholine-4-carbonyl)-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3-carboxamide, space group i23 |
|
125
|
313
|
5seoA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[2-(5-methyl-2-phenyl-1h-imidazol-4-yl)ethyl]isoindole-1,3-dione |
|
82
|
304
|
7matA |
Sars-cov-2 main protease (mpro) in complex with covalent inhibitor dffr |
|
123
|
313
|
5si4A |
Crystal structure of human phosphodiesterase 10 in complex with 3-(2-naphthalen-1-ylpyrazol-3-yl)-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one |
|
125
|
313
|
5se0A |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[2-(2-hydroxyethyl)-5-pyridin-2-ylpyrazol-3-yl]-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide |
|
126
|
313
|
5sktA |
Crystal structure of human phosphodiesterase 10 in complex with 7-(cyclopropylmethoxy)-2-methyl-4-pyrrolidin-1-ylquinazoline:hydrochloride |
|
124
|
313
|
5shvA |
Crystal structure of human phosphodiesterase 10 in complex with 1-(6-fluoropyridin-2-yl)piperidin-4-one |
|
122
|
313
|
5seyA |
Crystal structure of human phosphodiesterase 10 in complex with [2-cyclopropyl-6-[2-(1-methyl-4-phenylimidazol-2-yl)ethynyl]imidazo[1,2-b]pyridazin-3-yl]methanol |
|
123
|
313
|
5shtA |
Crystal structure of human phosphodiesterase 10 in complex with 8-chloro-5,7-dimethyl-2-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine |
|
128
|
313
|
5se3A |
Crystal structure of human phosphodiesterase 10 in complex with 2-chloro-n-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)pyridine-4-carboxamide |
|
123
|
313
|
5serA |
Crystal structure of human phosphodiesterase 10 in complex with 4-n-(2-fluoroethyl)-4-n,2-dimethyl-3-n-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)pyrazole-3,4-dicarboxamide |
|
125
|
316
|
5sguA |
Crystal structure of human phosphodiesterase 10 in complex with 12-methoxy-5,7-dimethyl-3-propyl-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(13),3,5,7,9,11-hexaene |
|
124
|
313
|
5sg1A |
Crystal structure of human phosphodiesterase 10 in complex with 2-[2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-a]quinoline |
|
132
|
313
|
5sjwA |
Crystal structure of human phosphodiesterase 10 in complex with 4-chloro-2-(2-methylpropyl)-n-(2-phenyl-1h-benzimidazol-5-yl)pyrazole-3-carboxamide |
|
126
|
313
|
5sfqA |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-n-[1-(2,2-difluoroethyl)pyrazol-3-yl]-2-methylpyrazole-3-carboxamide |
|
129
|
314
|
5shsA |
Crystal structure of human phosphodiesterase 10 in complex with 3-(naphthalen-1-ylmethyl)-7-piperidin-1-yltriazolo[4,5-d]pyrimidine |
|
123
|
313
|
5sgxA |
Crystal structure of human phosphodiesterase 10 in complex with 5,8-dimethyl-2-[2-[2-methyl-5-[(2r)-2-(trifluoromethyl)pyrrolidin-1-yl]-1,2,4-triazol-3-yl]ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine |
|
125
|
313
|
5sh1A |
Crystal structure of human phosphodiesterase 10 in complex with 5-methyl-2-phenyl-4-(2-quinolin-8-yloxyethyl)-1,3-oxazole |
|
124
|
313
|
5sggA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[(4-chloro-3,5-dimethylpyridin-2-yl)methylsulfanyl]-6,7-dihydro-3h-furo[3,2-f]benzimidazole |
|
128
|
313
|
5sg2A |
Crystal structure of human phosphodiesterase 10 in complex with 3-methylimidazo[4,5-f]quinolin-2-amine |
|
125
|
313
|
5sfmA |
Crystal structure of human phosphodiesterase 10 in complex with 2-methyl-4-(morpholine-4-carbonyl)-n-(2-phenyl-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl)pyrazole-3-carboxamide |
|
130
|
313
|
5sfkA |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-3-(pyrimidin-5-ylamino)-n-[1-(2,2,2-trifluoroethyl)pyrazol-3-yl]pyridine-2-carboxamide |
|
124
|
313
|
5sf8A |
Crystal structure of human phosphodiesterase 10 in complex with 4-(azetidine-1-carbonyl)-2-methyl-n-[2-(5-phenyl-2-pyridin-2-yl-1,2,4-triazol-3-yl)ethyl]pyrazole-3-carboxamide |
|
121
|
312
|
5sjgA |
Crystal structure of human phosphodiesterase 10 in complex with 1-[2-[2-(5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)ethyl]-1-methylimidazol-4-yl]pyrrolidin-2-one |
|
123
|
313
|
5skdA |
Crystal structure of human phosphodiesterase 10 in complex with 3-[2-(2,5-difluorophenyl)pyrazol-3-yl]-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one |
|
128
|
318
|
5sjuA |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[4-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]-3-(pyrimidin-5-ylamino)pyrazine-2-carboxamide |
|
124
|
316
|
5sisA |
Crystal structure of human phosphodiesterase 10 in complex with 4-n,2-dimethyl-4-n-[2-(methylamino)ethyl]-3-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3,4-dicarboxamide |
|
128
|
313
|
5sk1A |
Crystal structure of human phosphodiesterase 10 in complex with 4-n,2-dimethyl-3-n-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)pyrazole-3,4-dicarboxamide |
|
127
|
313
|
5sikA |
Crystal structure of human phosphodiesterase 10 in complex with 5-(cyclopentylmethoxy)pyrimidin-2-amine |
|
124
|
313
|
5sj1A |
Crystal structure of human phosphodiesterase 10 in complex with 7-[(3,5-dimethyl-4-propan-2-yloxypyridin-2-yl)methylsulfinyl]-6h-imidazo[4,5-g][1,3]benzothiazole |
|
124
|
313
|
5sk7A |
Crystal structure of human phosphodiesterase 10 in complex with 7-bromo-n,n-dimethyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine |
|
126
|
313
|
5sjqA |
Crystal structure of human phosphodiesterase 10 in complex with 6-chloro-2,3-dimethylquinoxaline |
|
127
|
313
|
5sflA |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-[5-[(2-hydroxy-2-methylpropyl)carbamoyl]-1-methylpyrazol-4-yl]-3-(pyrimidin-5-ylamino)pyrazine-2-carboxamide |
|
123
|
313
|
5shmA |
Crystal structure of human phosphodiesterase 10 in complex with n-[(3r)-1-(5-chloropyridin-2-yl)pyrrolidin-3-yl]-6-cyclopropyl-3-methoxypyrazine-2-carboxamide |
|
124
|
313
|
5sgbA |
Crystal structure of human phosphodiesterase 10 in complex with 5-(4-chloronaphthalen-1-yl)oxythiadiazole |
|
123
|
313
|
5sh9A |
Crystal structure of human phosphodiesterase 10 in complex with 2-[2-[5-[(3r)-3-fluoropyrrolidin-1-yl]-2-methyl-1,2,4-triazol-3-yl]ethyl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine |
|
125
|
313
|
5sjoA |
Crystal structure of human phosphodiesterase 10 in complex with 3-[2-(2,4-difluorophenyl)pyrazol-3-yl]-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one |
|
125
|
313
|
5sgdA |
Crystal structure of human phosphodiesterase 10 in complex with 4-(methoxymethyl)-2-methyl-n-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)pyrazole-3-carboxamide |
|
126
|
313
|
5sdxA |
Crystal structure of human phosphodiesterase 10 in complex with 4-[6-[2-(1-methyl-4-phenylimidazol-2-yl)ethyl]pyridin-2-yl]morpholine |
|
123
|
313
|
5sfgA |
Crystal structure of human phosphodiesterase 10 in complex with n-[(3r)-1-(5-chloropyridin-2-yl)pyrrolidin-3-yl]-6-cyclopropyl-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide |
|
127
|
312
|
5sgvA |
Crystal structure of human phosphodiesterase 10 in complex with 1-benzyl-3-(2-phenylpyrazol-3-yl)pyridazin-4-one |
|
125
|
313
|
5sj8A |
Crystal structure of human phosphodiesterase 10 in complex with 12-methoxy-5-methyl-3-propyl-2,4,8,13-tetrazatricyclo[7.4.0.02,6]trideca-1(13),3,5,7,9,11-hexaene-7-carbonitrile |
|
125
|
313
|
5sgrA |
Crystal structure of human phosphodiesterase 10 in complex with 2-chloro-3-[(1-methyl-4-phenylimidazol-2-yl)methoxy]quinoxaline |