|
91
|
293
|
4ap7A |
Crystal structure of c-met kinase domain in complex with 4-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl)phenol |
|
100
|
318
|
4agcA |
Crystal structure of vegfr2 (juxtamembrane and kinase domains) in complex with axitinib (ag-013736) (n-methyl-2-(3-((e)-2-pyridin-2-yl- vinyl)-1h-indazol-6-ylsulfanyl)-benzamide) |
|
91
|
293
|
3zc5A |
X-ray structure of c-met kinase in complex with inhibitor (s)-6-(1-(6- (1-methyl-1h-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)ethyl) quinoline. |
|
97
|
303
|
3wzeA |
Kdr in complex with ligand sorafenib |
|
88
|
287
|
3zmmA |
Inhibitors of jak2 kinase domain |
|
93
|
287
|
3zc6A |
Crystal structure of jak3 kinase domain in complex with an indazole substituted pyrrolopyrazine inhibitor |
|
82
|
274
|
3zfyA |
Crystal structure of ephb3 |
|
94
|
298
|
3wzdA |
Kdr in complex with ligand lenvatinib |
|
78
|
283
|
3zfxA |
Crystal structure of ephb1 |
|
90
|
296
|
3zbfA |
Structure of human ros1 kinase domain in complex with crizotinib |
|
76
|
280
|
3zewA |
Crystal structure of ephb4 in complex with staurosporine |
|
88
|
286
|
3zbxA |
X-ray structure of c-met kinase in complex with inhibitor 6-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) quinoline. |
|
93
|
293
|
3zclA |
X-ray structure of c-met kinase in complex with inhibitor (s)-3-(1-(1h-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-n-isopropyl-(1,2,4)triazolo(4,3- b)pyridazin-6-amine |
|
84
|
285
|
3zepA |
Crystal structure of jak3 kinase domain in complex with a pyrrolopyrazine-2-phenyl ether inhibitor |
|
78
|
279
|
3zfmA |
Crystal structure of ephb2 |
|
94
|
318
|
3w33A |
Egfr kinase domain complexed with compound 19b |
|
99
|
317
|
3w32A |
Egfr kinase domain complexed with compound 20a |
|
92
|
320
|
3w2rA |
Egfr kinase domain t790m/l858r mutant with compound 4 |
|
92
|
319
|
3w2sA |
Egfr kinase domain with compound4 |
|
97
|
321
|
3w2qA |
Egfr kinase domain t790m/l858r mutant with hki-272 |
|
99
|
322
|
3w2pA |
Egfr kinase domain t790m/l858r mutant with compound 2 |
|
94
|
328
|
3vw8A |
Crystal structure of human c-met kinase domain with its inhibitor |
|
95
|
321
|
3w2oA |
Egfr kinase domain t790m/l858r mutant with tak-285 |
|
117
|
447
|
3vs6A |
Crystal structure of hck complexed with a pyrazolo-pyrimidine inhibitor tert-butyl {4-[4-amino-1-(propan-2-yl)-1h-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl}carbamate |
|
102
|
307
|
3vntA |
Crystal structure of the kinase domain of human vegfr2 with a [1,3]thiazolo[5,4-b]pyridine derivative |
|
90
|
322
|
3vjnA |
Crystal structure of the mutated egfr kinase domain (g719s/t790m) in complex with amppnp. |
|
105
|
307
|
3vo3A |
Crystal structure of the kinase domain of human vegfr2 with imidazo[1,2-b]pyridazine derivative |
|
84
|
292
|
3v5qA |
Discovery of a selective trk inhibitor with efficacy in rodent cancer tumor models |
|
116
|
447
|
3vs2A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
122
|
447
|
3vryA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane |
|
90
|
323
|
3vjoA |
Crystal structure of the wild-type egfr kinase domain in complex with amppnp. |
|
110
|
447
|
3vs4A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 5-(4-phenoxyphenyl)-7-(tetrahydro-2h-pyran-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
123
|
447
|
3vs3A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
106
|
447
|
3vs7A |
Crystal structure of hck complexed with a pyrazolo-pyrimidine inhibitor 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine |
|
109
|
447
|
3vs0A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor n-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]benzamide |
|
112
|
447
|
3vs1A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea |
|
117
|
447
|
3vrzA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea |
|
116
|
447
|
3vs5A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
93
|
355
|
3vhkA |
Crystal structure of the vegfr2 kinase domain in complex with a back pocket binder |
|
70
|
264
|
3v8tA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 477 |
|
84
|
273
|
3vf8A |
Crystal structure of spleen tyrosine kinase syk catalytic domain with pyrazolylbenzimidazole inhibitor 416 |
|
79
|
272
|
3vf9A |
Crystal structure of spleen tyrosine kinase syk catalytic domain with thienopyrazolylindole inhibitor 027 |
|
75
|
262
|
3v5lA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 542 |
|
88
|
356
|
3vidA |
Crystal structure of human vegfr2 kinase domain with compound a. |
|
65
|
265
|
3v8wA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 469 |
|
103
|
359
|
3vheA |
Crystal structure of human vegfr2 kinase domain with a novel pyrrolopyrimidine inhibitor. |
|
66
|
264
|
3v5jA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 090 |
|
95
|
287
|
3ugcA |
Structural basis of jak2 inhibition by the type ii inhibtor nvp-bbt594 |
|
86
|
322
|
3ug1A |
Crystal structure of the mutated egfr kinase domain (g719s/t790m) in the apo form |
|
85
|
276
|
3uqgA |
C-src kinase domain in complex with bumpless bki analog uw1243 |
