|
35
|
186
|
1yhoA |
Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures |
|
12
|
60
|
1vieA |
Structure of dihydrofolate reductase |
|
54
|
205
|
1vj3A |
Structural studies on bio-active compounds. crystal structure and molecular modeling studies on the pneumocystis carinii dihydrofolate reductase cofactor complex with tab, a highly selective antifolate. |
|
12
|
60
|
1vifA |
Structure of dihydrofolate reductase |
|
36
|
157
|
1vdrA |
Dihydrofolate reductase |
|
52
|
186
|
1u71A |
Understanding the role of leu22 variants in methotrexate resistance: comparison of wild-type and leu22arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and nadph |
|
48
|
186
|
1u72A |
Understanding the role of leu22 variants in methotrexate resistance: comparison of wild-type and leu22arg variant mouse and human dihydrfolate reductase ternary crystal complexes with methotrexate and nadph |
|
48
|
186
|
1u70A |
Understanding the role of leu22 variants in methotrexate resistance: comparison of wild-type and leu22arg variant mouse and human dihydrofolate reductase |
|
41
|
159
|
1tdrA |
Expression, characterization, and crystallographic analysis of telluromethionyl dihydrofolate reductase |
|
163
|
519
|
1sejA |
Crystal structure of dihydrofolate reductase-thymidylate synthase from cryptosporidium hominis bound to 1843u89/nadph/dump |
|
44
|
159
|
1rx5A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate |
|
46
|
159
|
1rx1A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with nicotinamide adenine dinucleotide phosphate (reduced form) |
|
53
|
186
|
1s3wA |
Structure determination of tetrahydroquinazoline antifoaltes in complex with human and pneumocystis carinii dihydrofolate reductase: correlations of enzyme selectivity and stereochemistry |
|
45
|
159
|
1rx2A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with with folate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
45
|
159
|
1rx4A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate and 2'-monophosphoadenosine 5'-diphosphoribose |
|
44
|
159
|
1rx8A |
Dihydrofolate reductase complexed with folate and 2'-monophosphoadenosine 5'-diphosphoribose |
|
48
|
159
|
1rx6A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate and nicotinamide adenine dinucleotide phosphate (reduced form) |
|
42
|
159
|
1rx7A |
Structure of dihydrofolate reductase complexed with folate |
|
44
|
159
|
1rx3A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (reduced form) |
|
51
|
206
|
1s3yA |
Structure determination of tetrahydroquinazoline antifolates in complex with human and pneumocystis carinii dihydrofolate reductase: correlations of enzyme selectivity and stereochemistry |
|
48
|
159
|
1rx9A |
Dihydrofolate reductase (e.c.1.5.1.3) complexed with nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
49
|
186
|
1s3vA |
Structure determination of tetrahydroquinazoline antifolates in complex with human and pneumocystis carinii dihydrofolate reductase: correlations of enzyme selectivity and stereochemistry |
|
52
|
186
|
1s3uA |
Structure determination of tetrahydroquinazoline antifolates in complex with human and pneumocystis carinii dihydrofolate reductase: correlations of enzyme selectivity and stereochemistry |
|
42
|
159
|
1rh3A |
Dihydrofolate reductase complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (reduced form) |
|
40
|
159
|
1rc4A |
Dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
42
|
159
|
1ra2A |
Dihydrofolate reductase complexed with folate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
42
|
159
|
1ra1A |
Dihydrofolate reductase complexed with nicotinamide adenine dinucleotide phosphate (reduced form) |
|
45
|
159
|
1rg7A |
Dihydrofolate reductase complexed with methotrexate |
|
43
|
159
|
1rb2A |
Dihydrofolate reductase complexed with folate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
42
|
159
|
1ra3A |
Dihydrofolate reductase complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
40
|
159
|
1ra8A |
Dihydrofolate reductase complexed with folate and 2-monophosphoadenosine 5'-diphosphoribose |
|
45
|
159
|
1rd7A |
Dihydrofolate reductase complexed with folate |
|
46
|
159
|
1rf7A |
Structure of dihydrofolate reductase complexed with dihydrofolate |
|
41
|
159
|
1rb3A |
Dihydrofolate reductase complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
42
|
159
|
1ra9A |
Dihydrofolate reductase complexed with nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
43
|
159
|
1re7A |
Dihydrofolate reductase complexed with folate |
|
166
|
519
|
1qzfA |
Crystal structure of dhfr-ts from cryptosporidium hominis |
|
53
|
186
|
1pd9A |
Analysis of three crystal structure determinations of a 5-methyl-6-n-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase |
|
50
|
186
|
1pdbA |
Analysis of three crystal structure determinations of a 5-methyl-6-n-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase |
|
50
|
186
|
1pd8A |
Analysis of three crystal structure determinations of a 5-methyl-6-n-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase |
|
43
|
186
|
1ohkA |
Human dihydrofolate reductase, orthorhombic (p21 21 21) crystal form |
|
41
|
186
|
1ohjA |
Human dihydrofolate reductase, monoclinic (p21) crystal form |
|
47
|
186
|
1mvtA |
Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine n9-c10 reverse-bridge antifolate binary complex with human dihydrofolate reductase |
|
48
|
186
|
1mvsA |
Analysis of two polymorphic forms of a pyrido[2,3-d]pyrimidine n9-c10 reverse-bridge antifolate binary complex with human dihydrofolate reductase |
|
34
|
162
|
1ludA |
Solution structure of dihydrofolate reductase complexed with trimethoprim and nadph, 24 structures |
|
50
|
205
|
1ly4A |
Analysis of quinazoline and pyrido[2,3d]pyrimidine n9-c10 reversed bridge antifolates in complex with nadp+ and pneumocystis carinii dihydrofolate reductase |
|
59
|
192
|
1m79A |
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-(4-methoxyphenoxy)-2,4-quinazolinediamine (gw1466) |
|
57
|
192
|
1m7aA |
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 7-[2-methoxy-1-(methoxymethyl)ethyl]-7h-pyrrolo[3,2-f] quinazoline-1,3-diamine (gw557) |
|
56
|
206
|
1ly3A |
Analysis of quinazoline and pyridopyrimidine n9-c10 reversed bridge antifolates in complex with nadp+ and pneumocystis carinii dihydrofolate reductase |
|
58
|
192
|
1m78A |
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-chloryl-2,4,6-quinazolinetriamine (gw1225) |