|
50
|
185
|
1kmvA |
Human dihydrofolate reductase complexed with nadph and (z)-6-(2-[2,5-dimethoxyphenyl]ethen-1-yl)-2,4-diamino-5-methylpyrido[2,3-d]pyrimidine (sri-9662), a lipophilic antifolate |
|
55
|
184
|
1kmsA |
Human dihydrofolate reductase complexed with nadph and 6-([5-quinolylamino]methyl)-2,4-diamino-5-methylpyrido[2,3-d]pyrimidine (sri-9439), a lipophilic antifolate |
|
52
|
203
|
1klkA |
Crystal structure of pneumocystis carinii dihydrofolate reductase ternary complex with pt653 and nadph |
|
47
|
159
|
1jomA |
The crystal structure of the binary complex between folinic acid (leucovorin) and e. coli dihydrofolate reductase |
|
50
|
193
|
1juvA |
Crystal structure analysis of dihydrofolate reductase from bacteriophage t4 |
|
103
|
326
|
1j3jC |
Double mutant (c59r+s108n) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with pyrimethamine, nadph, and dump |
|
60
|
192
|
1ia3A |
Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) is displaced by 5-[(4-tert-butylphenyl)sulfanyl]-2,4-quinazolinediamine (gw995) |
|
57
|
192
|
1ia1A |
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-(phenylsulfanyl)-2,4-quinazolinediamine (gw997) |
|
57
|
192
|
1ia2A |
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) and 5-[(4-methylphenyl)sulfanyl]-2,4-quinazolinediamine (gw578) |
|
60
|
192
|
1ia4A |
Candida albicans dihydrofolate reductase complex in which the dihydronicotinamide moiety of dihydro-nicotinamide-adenine-dinucleotide phosphate (nadph) is displaced by 5-{[4-(4-morpholinyl)phenyl]sulfanyl}-2,4-quinazolinediamin (gw2021) |
|
51
|
186
|
1hfqA |
Comparison of ternary crystal complexes of human dihydrofolate reductase with nadph and a classical antitumor furopyrimdine |
|
48
|
186
|
1hfpA |
Comparison of ternary crystal complexes of human dihydrofolate reductase with nadph and a classical antitumor furopyrimdine |
|
48
|
186
|
1hfrA |
Comparison of ternary crystal complexes of human dihydrofolate reductase with nadph and a classical antitumor furopyrimdine |
|
45
|
159
|
1jolA |
The crystal structure of the binary complex between folinic acid (leucovorin) and e. coli dihydrofolate reductase |
|
43
|
159
|
1dyjA |
Isomorphous crystal structures of escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate and 5,10-dideazatetrahydrofolate: mechanistic implications |
|
52
|
186
|
1dr6A |
Crystal structures of organomercurial-activated chicken liver dihydrofolate reductase complexes |
|
49
|
186
|
1dr1A |
2.2 angstroms crystal structure of chicken liver dihydrofolate reductase complexed with nadp+ and biopterin |
|
47
|
186
|
1dr5A |
Crystal structures of organomercurial-activated chicken liver dihydrofolate reductase complexes |
|
44
|
159
|
1draA |
Crystal structure of unliganded escherichia coli dihydrofolate reductase. ligand-induced conformational changes and cooperativity in binding |
|
57
|
205
|
1e26A |
Design, synthesis and x-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent. |
|
40
|
159
|
1drhA |
Isomorphous crystal structures of escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate and 5,10-dideazatetrahydrofolate: mechanistic implications |
|
47
|
186
|
1dr7A |
Crystal structures of organomercurial-activated chicken liver dihydrofolate reductase complexes |
|
56
|
205
|
1dyrA |
The structure of pneumocystis carinii dihydrofolate reductase to 1.9 angstroms resolution |
|
51
|
186
|
1drfA |
Crystal structure of human dihydrofolate reductase complexed with folate |
|
51
|
186
|
1dr3A |
2.3 angstroms crystal structure of chicken liver dihydrofolate reductase complexed with thionadp+ and biopterin |
|
44
|
159
|
1dyiA |
Isomorphous crystal structures of escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate and 5,10-dideazatetrahydrofolate: mechanistic implications |
|
43
|
159
|
1dreA |
Dihydrofolate reductase complexed with methotrexate and nicotinamide adenine dinucleotide phosphate (oxidized form) |
|
44
|
159
|
1dyhA |
Isomorphous crystal structures of escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate and 5,10-dideazatetrahydrofolate: mechanistic implications |
|
44
|
159
|
1drbA |
Crystal structure of unliganded escherichia coli dihydrofolate reductase. ligand-induced conformational changes and cooperativity in binding |
|
49
|
186
|
1dr4A |
Crystal structures of organomercurial-activated chicken liver dihydrofolate reductase complexes |
|
51
|
186
|
1dr2A |
2.3 angstroms crystal structure of chicken liver dihydrofolate reductase complexed with thionadp+ and biopterin |
|
40
|
159
|
1dg8A |
Dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph |
|
61
|
231
|
1j3kA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with wr99210, nadph, and dump |
|
42
|
159
|
1dg7A |
Dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and 4-bromo wr99210 |
|
56
|
206
|
1dajA |
Comparison of ternary complexes of pneumocystis carinii and wild type human dihydrofolate reductase with coenzyme nadph and a novel classical antitumor furo[2,3d]pyrimidine antifolate |
|
53
|
186
|
1dlrA |
Methotrexate-resistant variants of human dihydrofolate reductase with substitution of leucine 22: kinetics, crystallography and potential as selectable markers |
|
45
|
159
|
1dhiA |
Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase |
|
41
|
159
|
1ddsA |
Molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate |
|
56
|
182
|
1dhfA |
Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazofolate |
|
39
|
159
|
1dg5A |
Dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and trimethoprim |
|
50
|
164
|
1d1gA |
Dihydrofolate reductase from thermotoga maritima |
|
52
|
186
|
1dlsA |
Methotrexate-resistant variants of human dihydrofolate reductase with substitution of leucine 22: kinetics, crystallography and potential as selectable markers |
|
36
|
159
|
1ddrA |
Molecule: dihydrofolate reductase (e.c.1.5.1.3) complexed with methotrexate and urea |
|
44
|
159
|
1dhjA |
Long-range structural effects in a second-site revertant of a mutant dihydrofolate reductase |
|
38
|
159
|
1df7A |
Dihydrofolate reductase of mycobacterium tuberculosis complexed with nadph and methotrexate |
|
106
|
326
|
1j3kC |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with wr99210, nadph, and dump |
|
41
|
162
|
1disA |
Dihydrofolate reductase (e.c.1.5.1.3) complex with brodimoprim-4,6-dicarboxylate |
|
66
|
231
|
1j3jA |
Double mutant (c59r+s108n) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with pyrimethamine, nadph, and dump |
|
61
|
233
|
1j3iA |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with wr99210, nadph, and dump |
|
103
|
327
|
1j3iC |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with wr99210, nadph, and dump |
