|
87
|
295
|
3w0nA |
Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase aph(4)-ia, ternary complex with amp-pnp and hygromycin b |
|
71
|
291
|
3vn9A |
Rifined crystal structure of non-phosphorylated map2k6 in a putative auto-inhibition state |
|
104
|
359
|
3vugA |
Crystal structure of a cysteine-deficient mutant m2 in map kinase jnk1 |
|
116
|
447
|
3vs2A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
84
|
292
|
3v5qA |
Discovery of a selective trk inhibitor with efficacy in rodent cancer tumor models |
|
90
|
322
|
3vjnA |
Crystal structure of the mutated egfr kinase domain (g719s/t790m) in complex with amppnp. |
|
113
|
347
|
3vqhA |
Bromine sad partially resolves multiple binding modes for pka inhibitor h-89 |
|
105
|
307
|
3vo3A |
Crystal structure of the kinase domain of human vegfr2 with imidazo[1,2-b]pyridazine derivative |
|
102
|
307
|
3vntA |
Crystal structure of the kinase domain of human vegfr2 with a [1,3]thiazolo[5,4-b]pyridine derivative |
|
108
|
358
|
3vuhA |
Crystal structure of a cysteine-deficient mutant m3 in map kinase jnk1 |
|
95
|
358
|
3vulA |
Crystal structure of a cysteine-deficient mutant m1 in map kinase jnk1 |
|
117
|
447
|
3vrzA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea |
|
71
|
280
|
3vquA |
Crystal structure of human mps1 catalytic domain in complex with 4-[(4-amino-5-cyano-6-ethoxypyridin-2- yl)amino]benzamide |
|
90
|
323
|
3vjoA |
Crystal structure of the wild-type egfr kinase domain in complex with amppnp. |
|
112
|
447
|
3vs1A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea |
|
116
|
447
|
3vs5A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
63
|
226
|
3vonA |
Crystalstructure of the ubiquitin protease |
|
122
|
447
|
3vryA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane |
|
104
|
358
|
3vukA |
Crystal structure of a cysteine-deficient mutant m5 in map kinase jnk1 |
|
94
|
358
|
3vudA |
Crystal structure of a cysteine-deficient mutant m1 in map kinase jnk1 |
|
123
|
447
|
3vs3A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
110
|
447
|
3vs4A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor 5-(4-phenoxyphenyl)-7-(tetrahydro-2h-pyran-4-yl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine |
|
106
|
447
|
3vs7A |
Crystal structure of hck complexed with a pyrazolo-pyrimidine inhibitor 1-cyclopentyl-3-(1h-pyrrolo[2,3-b]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine |
|
109
|
447
|
3vs0A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor n-[4-(4-amino-7-cyclopentyl-7h-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]benzamide |
|
93
|
355
|
3vhkA |
Crystal structure of the vegfr2 kinase domain in complex with a back pocket binder |
|
102
|
357
|
3v6rA |
Discovery of potent and selective covalent inhibitors of jnk |
|
81
|
322
|
3v04A |
Discovery of novel allosteric mek inhibitors possessing classical and non-classical bidentate ser212 interactions. |
|
205
|
639
|
3v5wA |
Human g protein-coupled receptor kinase 2 in complex with soluble gbetagamma subunits and paroxetine |
|
78
|
271
|
3vbyA |
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in pim-1 kinase needle screening and inhibitor design |
|
123
|
395
|
3v8sA |
Human rho-associated protein kinase 1 (rock 1) in complex with indazole derivative (compound 18) |
|
105
|
357
|
3v6sA |
Discovery of potent and selective covalent inhibitors of jnk |
|
84
|
273
|
3vf8A |
Crystal structure of spleen tyrosine kinase syk catalytic domain with pyrazolylbenzimidazole inhibitor 416 |
|
80
|
274
|
3vc4A |
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in pim-1 kinase needle screening and inhibitor design |
|
70
|
264
|
3v8tA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 477 |
|
97
|
357
|
3v3vA |
Structural and functional analysis of quercetagetin, a natural jnk1 inhibitor |
|
157
|
566
|
3utoA |
Twitchin kinase region from c.elegans (fn31-nl-kin-crd-ig26) |
|
79
|
272
|
3vf9A |
Crystal structure of spleen tyrosine kinase syk catalytic domain with thienopyrazolylindole inhibitor 027 |
|
75
|
262
|
3v5lA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 542 |
|
100
|
299
|
3uzrA |
Crystal structure of aminoglycoside phosphotransferase aph(2'')-ib, apo form |
|
157
|
465
|
3v5pA |
Calcium-dependent protein kinase 1 from toxoplasma gondii (tgcdpk1) in complex with inhibitor uw1288 |
|
148
|
465
|
3v5tA |
Calcium-dependent protein kinase 1 from toxoplasma gondii (tgcdpk1) in complex with inhibitor uw1299 |
|
96
|
292
|
3uzpA |
Crystal structure of ck1d with pf670462 from p21 crystal form |
|
81
|
271
|
3vbvA |
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in pim-1 kinase needle screening and inhibitor design |
|
65
|
265
|
3v8wA |
Crystal structure of interleukin-2 inducible t-cell kinase itk catalytic domain with thienopyrazolylindole inhibitor 469 |
|
90
|
290
|
3uytA |
Crystal structure of ck1d with pf670462 from p1 crystal form |
|
81
|
271
|
3vbtA |
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in pim-1 kinase needle screening and inhibitor design |
|
83
|
291
|
3uysA |
Crystal structure of apo human ck1d |
|
106
|
348
|
3uvpA |
Human p38 map kinase in complex with a benzamide substituted benzosuberone |
|
88
|
356
|
3vidA |
Crystal structure of human vegfr2 kinase domain with compound a. |
|
76
|
262
|
3vapA |
Synthesis and sar studies of imidazo-[1,2-a]-pyrazine aurora kinase inhibitors with improved off target kinase selectivity |
