50
|
257
|
1gj5H |
Selectivity at s1, h2o displacement, upa, tpa, ser190/ala190 protease, structure-based drug design |
53
|
257
|
1ghvH |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
53
|
257
|
1ghyH |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
1
|
36
|
1ghyL |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
1
|
36
|
1ghwL |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
3
|
28
|
1gj4L |
Selectivity at s1, h2o displacement, upa, tpa, ser190/ala190 protease, structure-based drug design |
52
|
257
|
1ghwH |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
52
|
257
|
1ghxH |
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site |
52
|
258
|
1gj4H |
Selectivity at s1, h2o displacement, upa, tpa, ser190/ala190 protease, structure-based drug design |
56
|
259
|
1jmoH |
Crystal structure of the heparin cofactor ii-s195a thrombin complex |
3
|
36
|
1fphL |
The interaction of thrombin with fibrinogen: a structural basis for its specificity |
3
|
27
|
1g32A |
Thrombin inhibitor complex |
3
|
26
|
1fpcL |
Active site mimetic inhibition of thrombin |
3
|
27
|
1g30A |
Thrombin inhibitor complex |
53
|
256
|
1fpcH |
Active site mimetic inhibition of thrombin |
62
|
259
|
1g30B |
Thrombin inhibitor complex |
4
|
45
|
1jouA |
Crystal structure of native s195a thrombin with an unoccupied active site |
59
|
287
|
1g37A |
Crystal structure of human alpha-thrombin complexed with bch-10556 and exosite-directed peptide |
55
|
259
|
1fphH |
The interaction of thrombin with fibrinogen: a structural basis for its specificity |
63
|
259
|
1g32B |
Thrombin inhibitor complex |
4
|
36
|
1ettL |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
2
|
36
|
1etrL |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
1
|
36
|
1etsL |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
70
|
289
|
1eojA |
Design of p1' and p3' residues of trivalent thrombin inhibitors and their crystal structures |
53
|
259
|
1etsH |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
50
|
259
|
1ettH |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
51
|
259
|
1etrH |
Refined 2.3 angstroms x-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors napap, 4-tapap and mqpa: a starting point for improving antithrombotics |
67
|
289
|
1eolA |
Design of p1' and p3' residues of trivalent thrombin inhibitors and their crystal structures |
3
|
27
|
1eb1L |
Complex structure of human thrombin with n-methyl-arginine inhibitor |
60
|
257
|
1eb1H |
Complex structure of human thrombin with n-methyl-arginine inhibitor |
3
|
28
|
1dweL |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
3
|
29
|
1dwbL |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
3
|
29
|
1dwcL |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
1
|
36
|
1e0fA |
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite ii-binding inhibitor |
61
|
259
|
1dx5M |
Crystal structure of the thrombin-thrombomodulin complex |
3
|
36
|
1dx5A |
Crystal structure of the thrombin-thrombomodulin complex |
56
|
257
|
1dwbH |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
54
|
257
|
1dwdH |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
72
|
295
|
1dojA |
Crystal structure of human alpha-thrombin*rwj-51438 complex at 1.7 a |
54
|
257
|
1dweH |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
3
|
29
|
1dwdL |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
54
|
257
|
1dwcH |
Crystallographic analysis at 3.0-angstroms resolution of the binding to human thrombin of four active site-directed inhibitors |
52
|
257
|
1e0fD |
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite ii-binding inhibitor |
5
|
28
|
1d4pA |
Crystal structure of human alpha thrombin in complex with 5-amidinoindole-4-benzylpiperidine inhibitor |
6
|
28
|
1d3pA |
Crystal structure of human aplha-thrombin in complex with benzo[b]thiophene inhibitor 3 |
2
|
33
|
1dm4A |
Ser195ala mutant of human thrombin complexed with fibrinopeptide a (7-16) |
7
|
28
|
1d3dA |
Crystal structure of human alpha thrombin in complex with benzothiophene inhibitor 4 |
63
|
257
|
1d4pB |
Crystal structure of human alpha thrombin in complex with 5-amidinoindole-4-benzylpiperidine inhibitor |
65
|
257
|
1d3dB |
Crystal structure of human alpha thrombin in complex with benzothiophene inhibitor 4 |
64
|
287
|
1d6wA |
Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at p1 |