|
41
|
160
|
3tq9A |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with methotrexate |
|
43
|
160
|
3tqaA |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with nadph |
|
37
|
160
|
3tqbA |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with folate |
|
44
|
173
|
3tq8A |
Structure of the dihydrofolate reductase (fola) from coxiella burnetii in complex with trimethoprim |
|
56
|
202
|
3td8A |
Structural analysis of pneumocystis carinii dihydrofolate reductase complex with nadph and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine |
|
41
|
157
|
3sruX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
40
|
157
|
3srrX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
42
|
157
|
3srsX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
43
|
157
|
3srqX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3sqyX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
40
|
157
|
3sr5X |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
41
|
157
|
3srwX |
S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines |
|
40
|
157
|
3sgyA |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006) |
|
41
|
157
|
3sh2A |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (ucp120j) |
|
53
|
186
|
3s7aA |
Human dihydrofolate reductase binary complex with pt684 |
|
52
|
186
|
3s3vA |
Human dihydrofolate reductase q35k/n64f double mutant binary complex with trimethoprim |
|
62
|
225
|
3roaA |
Candida glabrata dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(morpholin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1004) |
|
59
|
225
|
3ro9A |
Candida glabrata dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006) |
|
58
|
218
|
3rg9A |
Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210 |
|
42
|
166
|
5u27A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p65 inhibitor |
|
41
|
166
|
5u26A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p218 inhibitor |
|
40
|
157
|
5hf0X |
Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106) |
|
52
|
186
|
5ht4A |
6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl) |
|
37
|
161
|
5hi6A |
The high resolution structure of dihydrofolate reductase from yersinia pestis complex with methotrexate as closed form |
|
42
|
157
|
5hf2X |
Staphylococcus aureus dihydrofolate reductase complexed with cyclized alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1175) |
|
36
|
161
|
5fdaA |
The high resolution structure of apo form dihydrofolate reductase from yersinia pestis at 1.55 a |
|
39
|
149
|
5dxvA |
Crystal structure of rethreaded dhfr |
|
45
|
159
|
5eajA |
Crystal structure of dhfr in 0% isopropanol |
|
47
|
157
|
5eccA |
Klebsiella pneumoniae dfra1 complexed with nadph and 6-ethyl-5-(3-(2-methoxy-5-(pyridin-4-yl)phenyl)prop-1-yn-1-yl)pyrimidine-2,4-diamine |
|
45
|
159
|
5e8qA |
Crystal structure of dhfr in 20% isopropanol |
|
47
|
157
|
5ecxA |
Klebsiella pneumoniae dfra1 complexed with nadph and 6-ethyl-5-(3-(6-(pyridin-4-yl)benzo[d][1,3]dioxol-4-yl)but-1-yn-1-yl)pyrimidine-2,4-diamine |
|
40
|
159
|
5dfrA |
Crystal structure of unliganded escherichia coli dihydrofolate reductase. ligand-induced conformational changes and cooperativity in binding |
|
83
|
246
|
4xt7A |
Crystal structure of rv2671 from mycobacterium tuberculosis in complex with nadp+ and trimethoprim |
|
76
|
246
|
4xt6A |
Crystal structure of rv2671 from mycobacterium tuberculosis in complex with the tetrahydropteridine ring of tetrahydrofolate (thf) |
|
40
|
157
|
4xe6X |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1061) |
|
83
|
246
|
4xt4A |
Crystal structure of rv2671 from mycobacteirum tuberculosis in complex with dihydropteridine ring of dihydropteroic acid |
|
80
|
249
|
4xrbA |
Crystal structure of rv2671 from mycobacterium tuberculosis |
|
82
|
246
|
4xt8A |
Crystal structure of rv2671 from mycobacterium tuberculosis in complex with nadp+ and trimetrexate |
|
79
|
246
|
4xt5A |
Crystal structure of rv2671 from mycobacterium tuberculosis in complex with nadp+ |
|
40
|
157
|
4xecX |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1061) |
|
38
|
159
|
4x5jA |
Ecdhfr complexed with folate and nadp+ at 750 mpa |
|
43
|
159
|
4x5iA |
Ecdhfr complexed with folate and nadp+ at 660 mpa |
|
44
|
159
|
4x5fA |
Ecdhfr complexed with folate and nadp+ at 0.1 mpa |
|
42
|
159
|
4x5gA |
Ecdhfr complexed with folate and nadp+ at 270 mpa |
|
44
|
159
|
4x5hA |
Ecdhfr complexed with folate and nadp+ at 500 mpa |
|
41
|
157
|
4tu5X |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1062) |
|
56
|
206
|
4qjzD |
Pneumocystis carinii dihydrofolate reductase ternary complex with nadph and the inhibitor 24, (n~6~-methyl-n~6~-(naphthalen-1-yl)pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
54
|
186
|
4qhvA |
Crystal structure of human dihydrofolate reductase as complex with pyridopyrimidine 22 (n~6~-methyl-n~6~-[4-(propan-2-yl)phenyl]pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
50
|
186
|
4qjcA |
Human dihydrofolate reductase ternary complex with nadph and inhibitor 26 (n~6~-methyl-n~6~-(3,4,5-trifluorophenyl)pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
41
|
167
|
4qi9A |
Crystal structure of dihydrofolate reductase from yersinia pestis complexed with methotrexate |
