Found 291 chains in Genus chains table. Displaying 51 - 100. Applied filters: Proteins

Search results query ec: 3.4.21.6

Total Genus Sequence Length pdb Title
12 52 3q3kB Factor xa in complex with a phenylenediamine derivative
62 233 3q3kA Factor xa in complex with a phenylenediamine derivative
12 52 3m36L Factor xa in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-n-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (dpc423)
13 52 3m37L Factor xa in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-n-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (dpc602)
61 234 3m36A Factor xa in complex with the inhibitor 1-[3-(aminomethyl)phenyl]-n-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (dpc423)
58 234 3m37A Factor xa in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-n-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (dpc602)
12 51 3liwB Factor xa in complex with (r)-2-(1-adamantylcarbamoylamino)-3-(3-carbamidoyl-phenyl)-n-phenethyl-propionic acid amide
57 234 3liwA Factor xa in complex with (r)-2-(1-adamantylcarbamoylamino)-3-(3-carbamidoyl-phenyl)-n-phenethyl-propionic acid amide
13 52 3kqeL Factor xa in complex with the inhibitor 3-methyl-1-(3-(5- oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'- (pyrrolidin-1-ylmethyl)biphenyl-4-yl)-5,6-dihydro-1h- pyrazolo[3,4-c]pyridin-7(4h)-one
60 234 3kqbA Factor xa in complex with the inhibitor n-(3-fluoro-2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-1h- pyrazole-5-carboxamide
12 50 3kl6B Discovery of tetrahydropyrimidin-2(1h)-one derivative tak-442: a potent, selective and orally active factor xa inhibitor
12 52 3kqcL Factor xa in complex with the inhibitor 6-(2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6- dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
60 234 3kqcA Factor xa in complex with the inhibitor 6-(2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6- dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
60 234 3kqeA Factor xa in complex with the inhibitor 3-methyl-1-(3-(5- oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'- (pyrrolidin-1-ylmethyl)biphenyl-4-yl)-5,6-dihydro-1h- pyrazolo[3,4-c]pyridin-7(4h)-one
54 232 3kl6A Discovery of tetrahydropyrimidin-2(1h)-one derivative tak-442: a potent, selective and orally active factor xa inhibitor
55 234 3kqdA Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one
18 89 3k9xA X-ray crystal structure of human fxa in complex with (s)-n-((2-methylbenzofuran-5-ylamino)(2-oxo-1-(2-oxo-2- (pyrrolidin-1-yl)ethyl)azepan-3- ylamino)methylene)nicotinamide
10 52 3kqdL Factor xa in complex with the inhibitor 1-(3-(5-oxo-4,5- dihydro-1h-1,2,4-triazol-3-yl)phenyl)-6-(2'-(pyrrolidin-1- ylmethyl)biphenyl-4-yl)-3-(trifluoromethyl)-5,6-dihydro- 1h-pyrazolo[3,4-c]pyridin-7(4h)-one
12 52 3kqbL Factor xa in complex with the inhibitor n-(3-fluoro-2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-1h- pyrazole-5-carboxamide
61 238 3k9xB X-ray crystal structure of human fxa in complex with (s)-n-((2-methylbenzofuran-5-ylamino)(2-oxo-1-(2-oxo-2- (pyrrolidin-1-yl)ethyl)azepan-3- ylamino)methylene)nicotinamide
12 54 3iitB Factor xa in complex with a cis-1,2-diaminocyclohexane derivative
64 233 3iitA Factor xa in complex with a cis-1,2-diaminocyclohexane derivative
63 238 3hptB Crystal structure of human fxa in complex with (s)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
17 89 3hptA Crystal structure of human fxa in complex with (s)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine
58 234 3ffgA Factor xa in complex with the inhibitor (r)-6-(2'-((3- hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one
13 52 3ffgL Factor xa in complex with the inhibitor (r)-6-(2'-((3- hydroxypyrrolidin-1-yl)methyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin- 7(4h)-one
64 238 3ensB Crystal structure of human fxa in complex with methyl (2z)-3-[(3-chloro-1h-indol-7-yl)amino]-2-cyano-3-{[(3s)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
19 89 3ensA Crystal structure of human fxa in complex with methyl (2z)-3-[(3-chloro-1h-indol-7-yl)amino]-2-cyano-3-{[(3s)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
13 52 3cs7L Factor xa in complex with the inhibitor 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
60 234 3cs7A Factor xa in complex with the inhibitor 1-(4-methoxyphenyl)-6-(4-(1-(pyrrolidin-1-ylmethyl)cyclopropyl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
63 234 3cenA Factor xa in complex with the inhibitor n-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2h)-pyridinyl)benzamide
13 52 3cenL Factor xa in complex with the inhibitor n-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2h)-pyridinyl)benzamide
65 234 2y80A Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
61 234 2y7xA The discovery of potent and long-acting oral factor xa inhibitors with tetrahydroisoquinoline and benzazepine p4 motifs
12 52 2y7xB The discovery of potent and long-acting oral factor xa inhibitors with tetrahydroisoquinoline and benzazepine p4 motifs
62 233 2y5fA Factor xa - cation inhibitor complex
63 234 2y7zA Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
13 52 2y82B Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
12 54 2y5gL Factor xa - cation inhibitor complex
62 234 2y82A Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
12 54 2y5fL Factor xa - cation inhibitor complex
62 233 2y81A Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
12 54 2y5hL Factor xa - cation inhibitor complex
12 52 2y7zB Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
63 233 2y5gA Factor xa - cation inhibitor complex
12 52 2y81B Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
12 52 2y80B Structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine p4 motifs
64 233 2y5hA Factor xa - cation inhibitor complex
9 50 2xc0L Factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
61 234 2xbyA Factor xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor