0
|
16
|
2f9vD |
Hcv ns3 protease domain with ns4a peptide and a ketoamide inhibitor with p1 and p2 cyclopropylalannines |
0
|
16
|
2gvfD |
Hcv ns3-4a protease domain complexed with a macrocyclic ketoamide inhibitor, sch419021 |
187
|
566
|
1nb7A |
Hc-j4 rna polymerase complexed with short rna template strand |
113
|
435
|
2f55A |
Two hepatitis c virus ns3 helicase domains complexed with the same strand of dna |
148
|
437
|
3kqlA |
Three conformational snapshots of the hepatitis c virus ns3 helicase reveal a ratchet translocation mechanism |
154
|
437
|
3kqnA |
Three conformational snapshots of the hepatitis c virus ns3 helicase reveal a ratchet translocation mechanism |
148
|
437
|
3kquA |
Three conformational snapshots of the hepatitis c virus ns3 helicase reveal a ratchet translocation mechanism |
142
|
436
|
3kqhA |
Three conformational snapshots of the hepatitis c virus ns3 helicase reveal a ratchet translocation mechanism |
138
|
436
|
3kqkA |
Three conformational snapshots of the hepatitis c virus ns3 helicase reveal a ratchet translocation mechanism |
209
|
645
|
3o8cA |
Visualizing atp-dependent rna translocation by the ns3 helicase from hcv |
212
|
645
|
3o8rA |
Visualizing atp-dependent rna translocation by the ns3 helicase from hcv |
196
|
535
|
4wtgA |
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate with s15g e86q e87q c223h v321i mutations and delta8 beta hairpin loop deletion in complex with sofosbuvir diphosphate gs-607596, mn2+ and symmetrical primer template 5'-caaaauuu |
201
|
536
|
4wtfA |
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate with s15g e86q e87q c223h v321i mutations and delta8 beta hairpin loop deletion in complex with gs-639475, mn2+ and symmetrical primer template 5'-caaaauuu |
191
|
534
|
5uj2A |
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate with s15g e86q e87q c223h v321i mutations and delta8 neta hairpoin loop deletion in complex with gs-639476 (diphsohate version of gs-9813), mn2+ and symmetrical primer template 5'-auaaauuu |
201
|
547
|
5qj1A |
Crystal structure of the hepatitis c virus genotype 2a strain jfh1 l30s ns5b rna-dependent rna polymerase in complex with 6-(ethylamino)-2-(4-fluorophenyl)-5-(3-{[1-(5-fluoropyrimidin-2-yl)cyclopropyl]carbamoyl}-4-methoxyphenyl)-n-methyl-1-benzofuran-3-carboxamide |
204
|
569
|
5qj0A |
Crystal structure of the hepatitis c virus genotype 2a strain jfh1 ns5b rna-dependent rna polymerase in complex with 6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-n-methyl-5-(3-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide |
1
|
15
|
5kzpA |
Structure of the hcv1-c1 antibody-antigen complex |
0
|
10
|
5jziC |
Crystal structure of 1406 tcr bound to hla-a2 with hcv 1406-1415 antigen peptide |
142
|
435
|
8ohmA |
Crystal structure of rna helicase from genotype 1b hepatitis c virus: mechanism of unwinding duplex rna |
1
|
9
|
6bzwI |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the gl precursor of the broadly neutralizing antibody ap33 |
1
|
9
|
6bzuI |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the broadly neutralizing antibody 19b3 |
1
|
11
|
6bzyB |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the 22d11 broadly neutralizing antibody |
47
|
193
|
6bqkA |
Crystal structure of hepatis c virus protease (ns3) complexed with tripeptidic acyl sulfonamide inhibitor (compound 18) |
52
|
194
|
6bqjA |
Crystal structure of hepatis c virus protease (ns3) complexed with tripeptidic acyl sulfonamide inhibitor (compound 16) |
200
|
564
|
5w2eA |
Hcv ns5b rna-dependent rna polymerase in complex with non-nucleoside inhibitor mk-8876 |
46
|
198
|
5vojA |
Crystal structure of hcv ns3/4a protease in complex with jz01-15, an analogue of 5172-mcp1p3 |
203
|
562
|
4eo8A |
Hcv ns5b polymerase inhibitors: tri-substituted acylhydrazines as tertiary amide bioisosteres |
200
|
562
|
4eo6A |
Hcv ns5b polymerase inhibitors: tri-substituted acylhydrazines as tertiary amide bioisosteres |
193
|
563
|
4druA |
Hcv ns5b in complex with macrocyclic indole inhibitor |
209
|
562
|
4eawA |
Hcv ns5b in complex with idx375 |
199
|
544
|
4e76A |
Apo crystal structure of hcv ns5b genotype 2a jfh-1 isolate with beta hairpin loop deletion |
1
|
12
|
4dgyA |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the broadly neutralizing antibody hcv1, c2 form |
1
|
13
|
4dgvA |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the broadly neutralizing antibody hcv1, p2(1) form |
197
|
645
|
4b71A |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
208
|
645
|
4b75A |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
209
|
645
|
4b73A |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
208
|
645
|
4b74A |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
216
|
563
|
4aexA |
Hcv-jfh1 ns5b polymerase structure at 2.4 angstrom in a primitive orthorhombic space group |
211
|
645
|
4b76A |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
202
|
646
|
4b6eA |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
196
|
646
|
4b6fA |
Discovery of an allosteric mechanism for the regulation of hcv ns3 protein function |
51
|
194
|
4a1vA |
Co-complex structure of ns3-4a protease with the optimized inhibitory peptide cp5-46a-4d5e |
214
|
564
|
4adpA |
Hcv-j6 ns5b polymerase v405i mutant |
52
|
195
|
4a1xA |
Co-complex structure of ns3-4a protease with the inhibitory peptide cp5-46-a (synchrotron data) |
211
|
563
|
4aepA |
Hcv-jfh1 ns5b polymerase structure at 1.8 angstrom |
51
|
197
|
4a1tA |
Co-complex of the of ns3-4a protease with the inhibitory peptide cp5- 46-a (in-house data) |
200
|
639
|
4a92A |
Full-length hcv ns3-4a protease-helicase in complex with a macrocyclic protease inhibitor. |
201
|
553
|
3vqsA |
Crystal structure of hcv ns5b rna polymerase with a novel piperazine inhibitor |
203
|
568
|
3u4oA |
Novel hcv ns5b polymerase inhibitors: discovery of indole c2 acyl sulfonamides |
205
|
563
|
3udlA |
3-heterocyclyl quinolone bound to hcv ns5b |