|
155
|
383
|
8eh1A |
Engineered tyrosine synthase (tmtyrs1) derived from t. maritima trpb with ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline |
|
161
|
385
|
8egzA |
Engineered tyrosine synthase (tmtyrs1) derived from t. maritima trpb with ser bound as the amino-acrylate intermediate |
|
164
|
385
|
8eh0A |
Engineered tyrosine synthase (tmtyrs1) derived from t. maritima trpb with ser bound as the amino-acrylate intermediate and complexed with quinoline n-oxide |
|
92
|
267
|
8b06A |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 25 sec |
|
152
|
394
|
8b03B |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 0 sec |
|
96
|
269
|
8b03A |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 0 sec |
|
155
|
394
|
8b05B |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 20 sec |
|
94
|
268
|
8b05A |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 20 sec |
|
149
|
394
|
8b08B |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 30 sec |
|
152
|
394
|
8b06B |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 25 sec |
|
97
|
269
|
8b08A |
Tryptophan synthase - cryo-trapping by the spitrobot crystal plunger after 30 sec |
|
141
|
384
|
7rnpA |
Engineered tryptophan synthase b-subunit from pyrococcus furiosus, pftrpb2b9_h275e with 4-cl-trp non-covalently bound |
|
139
|
385
|
7rofA |
Engineered tryptophan synthase b-subunit from pyrococcus furiosus, pftrpb2b9-h275e with l-trp non-covalently bound |
|
138
|
385
|
7rnqA |
Holo structure of engineered trpb, 2b9-h275e, from pyrococcus furiosus in the extended-open conformation |
|
156
|
395
|
7kmcB |
The internal aldimine crystal structure of the beta-k167t mutant tryptophan synthase at 1.50 angstrom resolution with cesium ion at the metal coordination site |
|
98
|
268
|
7kmcA |
The internal aldimine crystal structure of the beta-k167t mutant tryptophan synthase at 1.50 angstrom resolution with cesium ion at the metal coordination site |
|
158
|
395
|
7ki7B |
The external aldimine crystal structure of the beta-k167t mutant tryptophan synthase at 1.75 angstrom resolution in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site and cesium ion at the metal coordination site |
|
107
|
268
|
7kh6A |
1.45 angstrom resolution internal aldimine crystal structure of the beta-q114a mutant of tryptophansynthase in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site and cesium ion at the metal coordination site |
|
100
|
268
|
7ki7A |
The external aldimine crystal structure of the beta-k167t mutant tryptophan synthase at 1.75 angstrom resolution in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site and cesium ion at the metal coordination site |
|
156
|
394
|
7kh6B |
1.45 angstrom resolution internal aldimine crystal structure of the beta-q114a mutant of tryptophansynthase in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site and cesium ion at the metal coordination site |
|
96
|
267
|
7me8A |
The internal aldimine form of the wild-type salmonella typhimurium tryptophan synthase in complex with n-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (f6f) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-q114 rotamer conformation at 1.60 angstrom resolution |
|
153
|
393
|
7me8B |
The internal aldimine form of the wild-type salmonella typhimurium tryptophan synthase in complex with n-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (f6f) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-q114 rotamer conformation at 1.60 angstrom resolution |
|
164
|
395
|
7kbnB |
1.60 angstrom resolution crystal structure of the beta-q114a mutant of tryptophan synthase in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site |
|
99
|
268
|
7kbnA |
1.60 angstrom resolution crystal structure of the beta-q114a mutant of tryptophan synthase in complex with n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site |
|
100
|
268
|
7ka1A |
1.60 angstrom resolution crystal structure of the beta-q114a mutant tryptophan synthase in complex with inhibitor n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site |
|
163
|
395
|
7ka1B |
1.60 angstrom resolution crystal structure of the beta-q114a mutant tryptophan synthase in complex with inhibitor n-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (f9f) at the alpha-site, aminoacrylate at the beta site, and cesium ion at the metal coordination site |
|
92
|
268
|
7k5aA |
The external aldimine form of salmonella typhimurium tryptophan synthase mutant beta-q114a in complex with cesium ion at the metal coordination site. |
|
158
|
395
|
7k5aB |
The external aldimine form of salmonella typhimurium tryptophan synthase mutant beta-q114a in complex with cesium ion at the metal coordination site. |
|
157
|
395
|
7jllB |
The internal aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (f9f) at the alpha-site, cesium ion at the metal coordination site and l-tryptophan at the enzyme beta-site |
|
105
|
268
|
7jttA |
The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex f9 inhibitor at the alpha-site and cesium ion at the metal coordination site. the single beta-q114 rotamer conformation allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring |
|
159
|
395
|
7k0bB |
The internal aldimine form of salmonella typhimurium tryptophan synthase mutant beta-q114a with cesium ion at the metal coordination site. a random beta-p270l mutation was inserted during pcr step |
|
102
|
267
|
7jllA |
The internal aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (f9f) at the alpha-site, cesium ion at the metal coordination site and l-tryptophan at the enzyme beta-site |
|
156
|
395
|
7jqwB |
The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with cesium ion at the metal coordination site. the single beta-q114 rotamer conformation allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring |
|
93
|
268
|
7jqwA |
The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with cesium ion at the metal coordination site. the single beta-q114 rotamer conformation allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring |
|
157
|
396
|
7jttB |
The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex f9 inhibitor at the alpha-site and cesium ion at the metal coordination site. the single beta-q114 rotamer conformation allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring |
|
98
|
268
|
7k0bA |
The internal aldimine form of salmonella typhimurium tryptophan synthase mutant beta-q114a with cesium ion at the metal coordination site. a random beta-p270l mutation was inserted during pcr step |
|
155
|
395
|
7jhwB |
The internal aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (f9f) at the alpha-site and cesium ion at the metal coordination site |
|
101
|
268
|
7jhwA |
The internal aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-s377a in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (f9f) at the alpha-site and cesium ion at the metal coordination site |
|
162
|
396
|
6xinB |
The crystal structure of tryptophan synthase from salmonella enterica serovar typhimurium in complex with (2s)-3-amino-3-imino-2-phenyldiazenylpropanamide at the enzyme alpha-site. |
|
152
|
389
|
6wx3B |
High resolution tryptophan synthase crystal structure from salmonella typhimurium in complex with f9 inhibitor in the alpha-site, cesium ion at the metal coordination site and internal aldimine form. |
|
158
|
394
|
6x0cB |
Tryptophan synthase mutant beta-q114a in complex with cesium ion at the metal coordination site and aminoacrylate and benzimidazole at the enzyme beta site |
|
95
|
268
|
6x0cA |
Tryptophan synthase mutant beta-q114a in complex with cesium ion at the metal coordination site and aminoacrylate and benzimidazole at the enzyme beta site |
|
160
|
396
|
6xe3B |
Salmonella typhimurium tryptophan synthase beta-s377a mutant in complex with inhibitor f9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion iii e(c3) at the enzyme beta-site. |
|
99
|
267
|
6wduA |
The external aldimine form of the salmonella thypi wild-type tryptophan synthase in open conformation showing multiple side chain conformations for the residue beta q114 and sodium ion at the metal coordination site. one of the beta-q114 rotamer conformations allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring. |
|
101
|
268
|
6xe3A |
Salmonella typhimurium tryptophan synthase beta-s377a mutant in complex with inhibitor f9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion iii e(c3) at the enzyme beta-site. |
|
156
|
396
|
6wduB |
The external aldimine form of the salmonella thypi wild-type tryptophan synthase in open conformation showing multiple side chain conformations for the residue beta q114 and sodium ion at the metal coordination site. one of the beta-q114 rotamer conformations allows a hydrogen bond to form with the plp oxygen at the position 3 in the ring. |
|
156
|
395
|
6vfdB |
Tryptophan synthase mutant q114a in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site |
|
94
|
268
|
6vfdA |
Tryptophan synthase mutant q114a in complex with cesium ion at the metal coordination site and 2-aminophenol quinonoid at the enzyme beta site |
|
90
|
260
|
6u6cA |
Crystal structure of tryptophan synthase from m. tuberculosis - aminoacrylate- and gsk2-bound form |
|
163
|
405
|
6u6cB |
Crystal structure of tryptophan synthase from m. tuberculosis - aminoacrylate- and gsk2-bound form |
