|
94
|
289
|
9n9xA |
Structure of hpk1 with c5 bound at its active site |
|
76
|
287
|
9mzyA |
Crystal structure of human ripk1 with compound 22 |
|
92
|
293
|
9nacA |
Structure of hpk1 with c4 bound at its active site |
|
81
|
289
|
9mzxA |
Crystal structure of human ripk1 with compound 1 |
|
210
|
625
|
9mreA |
From dna-encoded library screening to am-9747 - an mta-cooperative prmt5 inhibitor with potent oral in vivo efficacy |
|
82
|
310
|
9mreB |
From dna-encoded library screening to am-9747 - an mta-cooperative prmt5 inhibitor with potent oral in vivo efficacy |
|
93
|
281
|
9cdxA |
Crystal structure of dlk with inhibitor bound |
|
97
|
281
|
9cdyA |
Crystal structure of dlk with inhibitor bound |
|
76
|
276
|
9dznA |
Kat6a myst domain complexed with a h3k14-coa bisubstrate inhibitor |
|
85
|
368
|
9b16A |
Cryo-em structure of human umtck1 in complex with adp and covalent inhibitor cki |
|
93
|
306
|
9edwA |
Crystal structure of yck2 from candida albicans in complex with inhibitor 1f: 7-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine |
|
85
|
306
|
9edvA |
Crystal structure of yck2 from candida albicans in complex with inhibitor 1e: 2-(4-fluorophenyl)-3-(pyridin-4-yl)imidazo[1,2-a]pyridine-7-carbonitrile |
|
100
|
305
|
9edyA |
Crystal structure of yck2 from candida albicans in complex with inhibitor 2b: 6-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine |
|
95
|
306
|
9edxA |
Crystal structure of yck2 from candida albicans in complex with inhibitor 2a: 2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile |
|
265
|
939
|
8twyA |
Structure of p110 alpha bound to (s)-1-(4-((2-(4-(4-(2-amino-4-(difluoromethyl)pyrimidin-5-yl)-6-(3-methylmorpholino)-1,3,5- triazin-2-yl)piperazin-1-yl)-2-oxoethoxy)methyl)piperidin-1-yl)prop-2-en-1-one (compound 9) |
|
217
|
824
|
9bpaA |
Human dna polymerase theta helicase domain in complex with inhibitor ab25583, tetramer form |
|
217
|
824
|
9bp9A |
Human dna polymerase theta helicase domain in complex with inhibitor ab25583, dimer form |
|
92
|
298
|
8kh7A |
Crystal structure of fgfr4 kinase domain with 8zc |
|
90
|
299
|
8kh8A |
Crystal structure of fgfr4(v550l) kinase domain with 8z |
|
89
|
299
|
8kh9A |
Crystal structure of fgfr4(v550m) kinase domain with 8z |
|
90
|
297
|
8kh6A |
Crystal structure of fgfr4 kinase domain with 8r |
|
88
|
269
|
7mu6A |
Ask1 bound to compound 28 |
|
45
|
158
|
8sifA |
Crystal structure of escherichia coli hppk in complex with bisubstrate inhibitor hp-101 |
|
50
|
162
|
8sk1A |
Bacillus anthracis hppk in complex with bisubstrate inhibitor hp-73 |
|
94
|
293
|
8tvnA |
Irak4 in complex with compound 23 |
|
94
|
296
|
8tx0A |
Irak4 in complex with compound |
|
85
|
263
|
8tu5A |
Bruton's tyrosine kinase in complex with covalent inhibitor compound 27 |
|
99
|
300
|
8uccA |
Irak4 in complex with compound 20 |
|
99
|
296
|
8tvmA |
Irak4 in complex with compound 24 |
|
93
|
296
|
8ucbA |
Irak4 in complex with compound 8 |
|
83
|
266
|
8tu3A |
Bruton's tyrosine kinase in complex with covalent inhibitor compound 10 |
|
89
|
266
|
8tu4A |
Bruton's tyrosine kinase in complex with covalent inhibitor compound 25 |
|
93
|
295
|
8uccB |
Irak4 in complex with compound 20 |
|
86
|
311
|
8gk5A |
Egfr(t790m/v948r) kinase in complex with osimertinib and benzimidazole allosteric inhibitor |
|
262
|
948
|
8sc8A |
Structure of pi3kg in complex with mtx-531 |
|
98
|
326
|
8sc7A |
Structure of egfr in complex with mtx-531 |
|
130
|
403
|
8uvlA |
Crystal structure of selective ire1a inhibitor 29 at the enzyme active site |
|
124
|
438
|
9c1wA |
Structure of akt2 with compound 3 |
|
81
|
289
|
9bhjA |
Mertk in complex with small molecule 6-{1-[([1,1'-biphenyl]-4-yl)carbamoyl]azetidin-3-yl}-3-[(1-methyl-1h-pyrazol-4-yl)amino]pyrazine-2-carboxamide |
|
83
|
289
|
9bhkA |
Mertk in complex with small molecule inhibitor 6-{1-[6-(3-hydroxy-3-methylbutoxy)-1,3-benzoxazol-2-yl]azetidin-3-yl}-3-[(1-methyl-1h-pyrazol-4-yl)amino]pyrazine-2-carboxamide |
|
109
|
386
|
8x8zA |
Crystal structure of rock2 with gns-2664 inhibitor |
|
107
|
387
|
8x8yA |
Crystal structure of rock2 with gns-2660 inhibitor |
|
111
|
388
|
8x92A |
Crystal structure of rock2 with gns-2666 inhibitor |
|
113
|
386
|
8x8xA |
Crystal structure of rock2 with gns-2591 inhibitor |
|
31
|
113
|
8uw9B |
Structure of akt1(e17k) with compound 4 |
|
124
|
419
|
8uw9A |
Structure of akt1(e17k) with compound 4 |
|
116
|
430
|
8uw7A |
Structure of akt1(wt) with compound 3 |
|
111
|
427
|
8uw2A |
Structure of akt1(e17k) with compound 3 (zinc-free) |
|
118
|
430
|
8uvyA |
Structure of akt1(e17k) with compound 3 |
|
24
|
115
|
8uw7B |
Structure of akt1(wt) with compound 3 |
