|
145
|
461
|
6eiyA |
Crystal structure of kdm5b in complex with kdopz000034a. |
|
142
|
459
|
6ej1A |
Crystal structure of kdm5b in complex with kdopz48a. |
|
101
|
350
|
6cg1A |
Crystal structure of kdm4a with compound 14 |
|
104
|
348
|
6cg2A |
Crystal structure of kdm4a with compound 8 |
|
85
|
318
|
6bh3A |
Linked kdm5a jmj domain bound to the inhibitor (s)-n-(1-(3-isopropyl-1h-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (compound n55) |
|
93
|
318
|
6bgyA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(1-methylpyrrolidin-2-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound 46) |
|
89
|
318
|
6bguA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine (compound n9) |
|
86
|
318
|
6bgzA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(1-methyl-1h-imidazol-2-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n47) |
|
88
|
317
|
6bh5A |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(3-(piperidin-1-yl)propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n48) |
|
88
|
318
|
6bgvA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n40) |
|
89
|
317
|
6bgxA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)((4,4-difluorocyclohexyl)methoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n42) |
|
84
|
318
|
6bh0A |
Linked kdm5a jmj domain bound to the inhibitor (r)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n51) |
|
86
|
318
|
6bh2A |
Linked kdm5a jmj domain bound to the inhibitor (r)-n-(1-(3-isopropyl-1h-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (compound n54) |
|
86
|
318
|
6bh1A |
Linked kdm5a jmj domain bound to the inhibitor (s)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n52) |
|
84
|
318
|
6bh4A |
Linked kdm5a jmj domain bound to the inhibitor 5-(1-(tert-butyl)-1h-pyrazol-4-yl)-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (compound n75/cpi-48) |
|
87
|
318
|
6bgwA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n41) |
|
158
|
547
|
5ykoA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain in complex with nog and h3k4me3 peptide |
|
148
|
547
|
5yknA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain |
|
105
|
345
|
5vgiA |
Crystal structure of kdm4 with the small molecule inhibitor qc6352 |
|
108
|
350
|
5vmpA |
Crystal structure of human kdm4 with small molecule inhibitor qc5714 |
|
107
|
350
|
5f37A |
Crystal structure of human kdm4a in complex with compound 58 |
|
161
|
774
|
5cehA |
Structure of histone lysine demethylase kdm5a in complex with selective inhibitor |
|
145
|
462
|
5a3nA |
Crystal structure of human plu-1 (jarid1b) in complex with kdoam25a |
|
150
|
462
|
5a3tA |
Crystal structure of human plu-1 (jarid1b) in complex with kdm5-c49 (2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl) isonicotinic acid). |
|
144
|
458
|
5a1fA |
Crystal structure of the catalytic domain of plu1 in complex with n-oxalylglycine. |
|
144
|
463
|
5a3pA |
Crystal structure of the catalytic domain of human plu1 (jarid1b). |
|
148
|
466
|
5a1lA |
Crystal structure of jmjc domain of human histone demethylase uty with s21056a |
|
109
|
349
|
4uraA |
Crystal structure of human jmjd2a in complex with compound 14a |
|
153
|
481
|
4ezhA |
The crystal structure of kdm6b bound with h3k27me3 peptide |
|
149
|
481
|
4eyuA |
The free structure of the mouse c-terminal domain of kdm6b |
|
136
|
481
|
4ez4A |
Free kdm6b structure |
|
103
|
363
|
4do0A |
Crystal structure of human phf8 in complex with daminozide |
|
99
|
327
|
4d6sA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound 5,6-dimethylbenzimidazole |
|
100
|
323
|
4d6rA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound o-toluenesulfonamide |
|
104
|
330
|
4d6qA |
Crystal structure of human jmjd2d in complex with 2,4-pdca |
|
103
|
341
|
4c8dA |
Crystal structure of jmjc domain of human histone 3 lysine-specific demethylase 3b (kdm3b) |
|
103
|
348
|
4bisA |
Jmjd2a complexed with 8-hydroxyquinoline-4-carboxylic acid |
|
148
|
462
|
4askA |
Crystal structure of jmjd3 with gsk-j1 |
|
150
|
465
|
3zliA |
Crystal structure of jmjc domain of human histone demethylase uty |
|
152
|
466
|
3zpoA |
Crystal structure of jmjc domain of human histone demethylase uty with bound gsk j1 |
|
107
|
348
|
4ai9A |
Jmjd2a complexed with daminozide |
|
106
|
345
|
3u4sA |
Histone lysine demethylase jmjd2a in complex with t11c peptide substrate crosslinked to n-oxalyl-d-cysteine |
|
108
|
366
|
3u78A |
E67-2 selectively inhibits kiaa1718, a human histone h3 lysine 9 jumonji demethylase |
|
107
|
351
|
3rvhA |
Crystal structure of jmjd2a complexed with inhibitor |
|
106
|
345
|
2q8cA |
Crystal structure of jmjd2a in ternary complex with an histone h3k9me3 peptide and 2-oxoglutarate |
|
105
|
344
|
2q8eA |
Specificity and mechanism of jmjd2a, a trimethyllysine-specific histone demethylase |
|
100
|
347
|
2q8dA |
Crystal structure of jmj2d2a in ternary complex with histone h3-k36me2 and succinate |
|
158
|
774
|
5v9pA |
Crystal structure of pyrrolidine amide inhibitor [(3s)-3-(4-bromo-1h-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1h-pyrazol-5-yl]methanone (compound 35) in complex with kdm5a |
|
147
|
774
|
5v9tA |
Crystal structure of selective pyrrolidine amide kdm5a inhibitor n-{(3r)-1-[3-(propan-2-yl)-1h-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48) |
|
107
|
348
|
5tvrA |
Jmjd2a in complex with ni(ii) and alpha-ketoglutarate |
