|
95
|
270
|
5lmaA |
Human spleen tyrosine kinase kinase domain in complex with azanaphthyridine inhibitor |
|
108
|
347
|
5lckA |
A clickable covalent erk 1/2 inhibitor |
|
93
|
290
|
4zimA |
Crystal structure of janus kinase 2 in complex with a 9h-carbazole-1-carboxamide inhibitor |
|
71
|
263
|
5aafA |
Aurora a kinase bound to an imidazopyridine inhibitor (14a) |
|
78
|
272
|
5c9cA |
Crystal structure of braf(v600e) in complex with ly3009120 compnd |
|
113
|
350
|
5larA |
Crystal structure of p38 alpha mapk14 in complex with vpc00628 |
|
88
|
308
|
5bvkA |
Fragment-based discovery of potent and selective ddr1/2 inhibitors |
|
95
|
289
|
4zjiA |
Pak1 in complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin-1-yl)-dibenzodiazepine |
|
102
|
289
|
4ytiA |
Discovery of vx-509 (decernotinib): a potent and selective janus kinase (jak) 3 inhibitor for the treatment of autoimmune disease |
|
109
|
297
|
5bylA |
Aminoglycoside phosphotransferase (2'')-ia (ctd of aac(6')-ie/aph(2'')-ia) in complex with gmppcp and magnesium |
|
70
|
277
|
5m55A |
Nek2 bound to arylaminopurine 71 |
|
90
|
274
|
5c27A |
Crystal structure of syk in complex with compound 2 |
|
81
|
289
|
5c01A |
Crystal structure of kinase |
|
88
|
325
|
5acbC |
Crystal structure of the human cdk12-cyclink complex |
|
111
|
340
|
5ke0A |
Discovery of 1-1h-pyrazolo 4,3-c pyridine-6-yl urea inhibitors of extracellular signal regulated kinase erk for the treatment of cancers |
|
84
|
275
|
5bmmA |
Src in complex with dna-templated macrocyclic inhibitor mc25b |
|
86
|
308
|
5bvwA |
Fragment-based discovery of potent and selective ddr1/2 inhibitors |
|
77
|
270
|
5jznA |
Crystal structure of dclk1-kd in complex with nvp-tae684 |
|
85
|
263
|
5j87A |
Discovery of n-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (chmfl-btk-01) as a highly selective irreversible btk kinase inhibitor |
|
88
|
268
|
5k3yA |
Crystal structure of aurorab/incenp in complex with bi 811283 |
|
84
|
296
|
5j95A |
Map4k4 in complex with inhibitor |
|
114
|
350
|
5bveA |
Tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase |
|
84
|
262
|
5jrsA |
Crystal structure of bruton agammaglobulinemia tyrosine kinase complexed with 4-[2-fluoro-3-(4-oxo -3,4-dihydroquinazolin-3-yl)phenyl]-7-(2-hydroxypropan-2-y l)-9h-carbazole-1-carboxamide |
|
98
|
312
|
5iuiA |
Crystal structure of anaplastic lyphoma kinase (alk) in complex with 4 |
|
89
|
309
|
5kz0A |
Structure of human anaplastic lymphoma kinase in complex with 2-[(1r)-1-{[2-amino-5-(1,3-dimethyl-1h-pyrazol-4-yl)pyridin-3-yl]oxy}ethyl]-4-fluoro-n,n-dimethylbenzamide |
|
116
|
348
|
5a3xA |
Dyrk1a in complex with hydroxy benzothiazole fragment |
|
78
|
306
|
5j8iA |
Crystal structure of tl11-113 bound to tak1-tab1 |
|
115
|
347
|
5hd7A |
Dissecting therapeutic resistance to erk inhibition rat mutant sch772984 in complex with (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide |
|
194
|
640
|
5he1A |
Human grk2 in complex with gbetagamma subunits and ccg224062 |
|
103
|
362
|
5hbeA |
Cdk8-cycc in complex with 8-[3-chloro-5-(1-methyl-2,2-dioxo-2, 3-dihydro-1h-2l6-benzo[c]isothiazol-5-yl)-pyridin- 4-yl]-1-oxa-3,8-diaza-spiro[4.5]decan-2-one |
|
79
|
283
|
5hkmA |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
70
|
268
|
5hi2A |
Braf kinase domain b3ac loop deletion mutant in complex with sorafenib |
|
85
|
291
|
5hezA |
Jak2 kinase (jh1 domain) mutant p1057a in complex with tg101209 |
|
80
|
276
|
5ia5A |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with golvatinib (e7050) |
|
91
|
324
|
5hcyA |
Egfr kinase domain mutant "tmlr" with 3-carboxamide azaindole compound 13 |
|
89
|
305
|
5hvjA |
Crystal structure of limk1 d460n mutant in complex with amp-pnp |
|
91
|
306
|
5hhwA |
Crystal structure of insulin receptor kinase domain in complex with cis-(r)-7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(3-((tetrahydro-2h-pyran-2-yl)methoxy)phenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine. |
|
88
|
294
|
5i9uA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase |
|
113
|
331
|
5h8bA |
Crystal structure of ck2 with compound 2 |
|
83
|
288
|
5ho8A |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
99
|
347
|
5hlpA |
X-ray crystal structure of gsk3b in complex with brd3937 |
|
91
|
323
|
5hibA |
Egfr kinase domain mutant "tmlr" with a pyrazolopyrimidine inhibitor |
|
86
|
284
|
5hg9A |
Egfr (l858r, t790m, v948r) in complex with 1-[(3r,4r)-3-[({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one |
|
107
|
298
|
5iqaA |
Aminoglycoside phosphotransferase (2'')-ia (ctd of aac(6')-ie/aph(2'')-ia) in complex with gmppnp and magnesium |
|
90
|
323
|
5hcxA |
Egfr kinase domain mutant "tmlr" with azabenzimidazole compound 7 |
|
94
|
361
|
5hvyA |
Cdk8/cycc in complex with compound 20 |
|
91
|
323
|
5hicA |
Egfr kinase domain mutant "tmlr" with a imidazopyridinyl-aminopyrimidine inhibitor |
|
88
|
283
|
5hg7A |
Egfr (l858r, t790m, v948r) in complex with 1-{(3r,4r)-3-[5-chloro-2-(1-methyl-1h-pyrazol-4-ylamino)-7h-pyrrolo[2,3-d]pyrimidin-4-yloxymethyl]-4-methoxy-pyrrolidin-1-yl}propenone (pf-06459988) |
|
98
|
363
|
5hbhA |
Cdk8-cycc in complex with 5-{5-chloro-4-[1-(2-methoxy-ethyl)-1,8-diaza-spiro[4.5]dec-8-yl]-pyridin-3-yl}-1-methyl-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide |
|
203
|
639
|
5he0A |
Bovine grk2 in complex with gbetagamma subunits and ccg215022 |
