|
115
|
347
|
5hd7A |
Dissecting therapeutic resistance to erk inhibition rat mutant sch772984 in complex with (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide |
|
80
|
276
|
5ia5A |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with golvatinib (e7050) |
|
103
|
362
|
5hbeA |
Cdk8-cycc in complex with 8-[3-chloro-5-(1-methyl-2,2-dioxo-2, 3-dihydro-1h-2l6-benzo[c]isothiazol-5-yl)-pyridin- 4-yl]-1-oxa-3,8-diaza-spiro[4.5]decan-2-one |
|
203
|
639
|
5he0A |
Bovine grk2 in complex with gbetagamma subunits and ccg215022 |
|
83
|
288
|
5ho8A |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
79
|
283
|
5hkmA |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
70
|
268
|
5hi2A |
Braf kinase domain b3ac loop deletion mutant in complex with sorafenib |
|
85
|
291
|
5hezA |
Jak2 kinase (jh1 domain) mutant p1057a in complex with tg101209 |
|
91
|
324
|
5hcyA |
Egfr kinase domain mutant "tmlr" with 3-carboxamide azaindole compound 13 |
|
91
|
306
|
5hhwA |
Crystal structure of insulin receptor kinase domain in complex with cis-(r)-7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(3-((tetrahydro-2h-pyran-2-yl)methoxy)phenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine. |
|
113
|
331
|
5h8bA |
Crystal structure of ck2 with compound 2 |
|
89
|
305
|
5hvjA |
Crystal structure of limk1 d460n mutant in complex with amp-pnp |
|
74
|
294
|
5ho6A |
Crystal structure of cmet in complex with cmpd. |
|
99
|
347
|
5hlpA |
X-ray crystal structure of gsk3b in complex with brd3937 |
|
91
|
323
|
5hibA |
Egfr kinase domain mutant "tmlr" with a pyrazolopyrimidine inhibitor |
|
200
|
641
|
5he3A |
Bovine grk2 in complex with gbetagamma subunits and ccg224411 |
|
91
|
324
|
5hczA |
Egfr kinase domain mutant "tmlr" with 3-azetidinyl azaindazole compound 21 |
|
78
|
280
|
4zegA |
Crystal structure of ttk kinase domain in complex with a pyrazolopyrimidine inhibitor |
|
191
|
639
|
5he2A |
Bovine grk2 in complex with gbetagamma subunits and ccg224406 |
|
81
|
289
|
5hngA |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
92
|
300
|
5hg8A |
Egfr (l858r, t790m, v948r) in complex with n-[3-({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide |
|
105
|
326
|
5h8gA |
Crystal structure of ck2 with compound 7b |
|
65
|
297
|
5b2kA |
A crucial role of cys218 in the stabilization of an unprecedented auto-inhibition form of map2k7 |
|
78
|
269
|
5hidA |
Braf kinase domain b3ac loop deletion mutant in complex with az628 |
|
97
|
294
|
5hesA |
Human leucine zipper- and sterile alpha motif-containing kinase (zak, mlt, hccs-4, mrk, azk, mltk) in complex with vemurafenib |
|
86
|
297
|
5ikwA |
Crystal structure of bmp-2-inducible kinase in complex with an indazole inhibitor |
|
86
|
302
|
5i3oA |
Crystal structure of bmp-2-inducible kinase in complex with an indazole inhibitor |
|
84
|
269
|
5h9bA |
Drosophila camkii-wt in complex with a fragment of the eag potassium channel and mg2+/amppn |
|
71
|
292
|
5hoaA |
Crystal structure of c-met l1195v in complex with sar125844 |
|
97
|
362
|
5hnbA |
Cdk8-cycc in complex with [6-hydroxy-3-(3-methyl-benzyl)-1h-indazol-5-yl]-((s)-3-hydroxy-pyrrolidin-1-yl)-methanone |
|
114
|
403
|
5hgiA |
Crystal structure of apo human ire1 alpha |
|
91
|
302
|
5hg5A |
Egfr (l858r, t790m, v948r) in complex with n-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}prop-2-enamide |
|
115
|
331
|
5h8eA |
Crystal structure of ck2 with compound 7h |
|
108
|
345
|
4zzmA |
Human erk2 in complex with an irreversible inhibitor |
|
75
|
295
|
5fp5A |
Structure of cyclin-dependent kinase 2 with small-molecule ligand 4- fluorobenzoic acid (at222) in an alternate binding site. |
|
103
|
296
|
4yp8A |
Irak4-inhibitor co-structure |
|
98
|
313
|
5g6vA |
Crystal structure of the pctaire1 kinase in complex with inhibitor |
|
91
|
308
|
5fxsA |
Igfr-1r complex with a pyrimidine inhibitor. |
|
83
|
307
|
5gjgA |
Crystal structure of human tak1/tab1 fusion protein in complex with ligand 4 |
|
88
|
266
|
5h2uA |
Crystal structure of ptk6 kinase domain complexed with dasatinib |
|
91
|
306
|
5gjdA |
Crystal structure of human tak1/tab1 fusion protein in complex with ligand 2 |
|
86
|
296
|
5ax9A |
Crystal structure of the kinase domain of human traf2 and nck-interacting protein kinase in complex with compund 9 |
|
95
|
308
|
5fxqA |
Igfr-1r complex with a pyrimidine inhibitor. |
|
79
|
273
|
5ghvA |
Crystal structure of an inhibitor-bound syk |
|
86
|
307
|
5gjfA |
Crystal structure of human tak1/tab1 fusion protein in complex with ligand 3 |
|
95
|
312
|
5h3qA |
Crystal structure of trka kinase with ligand |
|
86
|
284
|
5gz9A |
Crystal structure of catalytic domain of protein o-mannosyl kinase in complexes with amp-pnp, magnesium ions and glycopeptide |
|
87
|
263
|
5g1xA |
Crystal structure of aurora-a kinase in complex with n-myc |
|
83
|
289
|
5gnkA |
Crystal structure of egfr 696-988 t790m in complex with lxx-6-34 |
|
107
|
356
|
5awmA |
The crystal structure of jnk from drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian jnk proteins. |
