|
82
|
230
|
3nhkA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
54
|
186
|
3ntzA |
Design, synthesis, biological evaluation and x-ray crystal structures of novel classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors |
|
117
|
420
|
3nw2A |
Novel nanomolar imidazopyridines as selective nitric oxide synthase (inos) inhibitors: sar and structural insights |
|
80
|
229
|
3nhrA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
145
|
427
|
3ng7X |
Complex of dithionite-reduced 6-hydroxy-l-nicotine oxidase with substrate bound at active site and inhibitor at exit cavity |
|
80
|
230
|
3nfrA |
Casimiroin analog inhibitor of quinone reductase 2 |
|
48
|
206
|
3nz6X |
Structural analysis of pneumocystis carinii and human dhfr complexes with nadph and a series of five potent 5-(omega-carboxy(alkyloxy)pyrido[2,3-d]pyrimidine derivatives |
|
80
|
230
|
3nhyA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
77
|
230
|
3nhwA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
77
|
230
|
3nhlA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
80
|
230
|
3nhfA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
205
|
552
|
3nt1A |
High resolution structure of naproxen:cox-2 complex. |
|
80
|
230
|
3nhsA |
X-ray crystallographic structure activity relationship (sar) of casimiroin and its analogs bound to human quinone reductase 2 |
|
147
|
425
|
3nn6X |
Crystal structure of inhibitor-bound in active centre 6-hydroxy-l-nicotine oxidase from arthrobacter nicotinovorans |
|
112
|
318
|
3ntyA |
Crystal structure of akr1c1 in complex with nadp and 5-phenyl,3-chlorosalicylic acid |
|
55
|
186
|
3nu0A |
Design, synthesis, biological evaluation and x-ray crystal structure of novel classical 6,5,6-tricyclicbenzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors |
|
133
|
416
|
3n6fA |
Structure of endothelial nitric oxide synthase n368d single mutant heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
130
|
418
|
3n61A |
Structure of neuronal nitric oxide synthase d597n/m336v mutant heme domain in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
126
|
418
|
3n65A |
Structure of neuronal nitric oxide synthase s602h mutant heme domain in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
127
|
418
|
3n63A |
Structure of neuronal nitric oxide synthase d597n/m336v mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
130
|
416
|
3n68A |
Structure of endothelial nitric oxide synthase heme domain n368d/v106m double mutant complexed with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl)-6-methylpyridin-2-amine |
|
133
|
416
|
3n5sA |
Structure of endothelial nitric oxide synthase heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine |
|
128
|
416
|
3n6aA |
Structure of endothelial nitric oxide synthase n368d/v106m double mutant heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine |
|
127
|
418
|
3n60A |
Structure of neuronal nitric oxide synthase heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
133
|
416
|
3n67A |
Structure of endothelial nitric oxide synthase n368d/v106m double mutant heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
130
|
418
|
3n62A |
Structure of neuronal nitric oxide synthase d597n mutant heme domain in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
103
|
416
|
3n6cA |
Structure of endothelial nitric oxide synthase h373s single mutant heme domain complexed with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine |
|
122
|
416
|
3n6dA |
Structure of endothelial nitric oxide synthase h373s single mutant heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
130
|
416
|
3n69A |
Structure of endothelial nitric oxide synthase n368d/v106m double mutant heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
115
|
416
|
3n6bA |
Structure of endothelial nitric oxide synthase h373s single mutant heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
128
|
418
|
3n64A |
Structure of neuronal nitric oxide synthase d597n mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
129
|
416
|
3n5tA |
Structure of endothelial nitric oxide synthase heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
126
|
416
|
3n5rA |
Structure of endothelial nitric oxide synthase heme domain complexed with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl)-6-methylpyridin-2-amine |
|
129
|
418
|
3n5zA |
Structure of neuronal nitric oxide synthase heme domain in complex with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine |
|
125
|
418
|
3n5vA |
Structure of neuronal nitric oxide synthase heme domain in complex with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl)-6-methylpyridin-2-amine |
|
130
|
418
|
3n5yA |
Structure of neuronal nitric oxide synthase heme domain in complex with 6,6'-(2,2'-(pyridine-2,6-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
127
|
418
|
3n66A |
Structure of neuronal nitric oxide synthase s602h mutant heme domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
130
|
418
|
3n5wA |
Structure of neuronal nitric oxide synthase heme domain in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
132
|
418
|
3n5xA |
Structure of neuronal nitric oxide synthase heme domain in complex with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine |
|
124
|
416
|
3n5qA |
Structure of endothelial nitric oxide synthase heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
126
|
416
|
3n5pA |
Structure of endothelial nitric oxide synthase heme domain complexed with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine |
|
130
|
416
|
3n6gA |
Structure of endothelial nitric oxide synthase n368d single mutant heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine |
|
130
|
416
|
3n6eA |
Structure of endothelial nitric oxide synthase n368d mutant heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine) |
|
107
|
314
|
3mb9A |
Human aldose reductase mutant t113a complexed with zopolrestat |
|
109
|
316
|
3m0iA |
Human aldose reductase mutant t113v in complex with zopolrestat |
|
41
|
161
|
3m09A |
F98y tmp-resistant dihydrofolate reductase from staphylococcus aureus with inhibitor rab1 |
|
40
|
161
|
3m08A |
Wild type dihydrofolate reductase from staphylococcus aureus with inhibitor rab1 |
|
107
|
316
|
3m4hA |
Human aldose reductase mutant t113v complexed with idd388 |
|
108
|
312
|
3lz3A |
Human aldose reductase mutant t113s complexed with idd388 |
|
105
|
312
|
3lz5A |
Human aldose reductase mutant t113v complexed with idd594 |
