|
133
|
329
|
4lljA |
Crystal structure of pde10a2 with fragment zt214 |
|
136
|
330
|
4lm2A |
Crystal structure of pde10a2 with fragment zt462 |
|
125
|
307
|
4mvhA |
Crystal structure of pde10a with novel keto-benzimidazole inhibitor |
|
125
|
330
|
4mseA |
Crystal structure of pde10a2 with fragment zt1597 (2-({[(2s)-2-methyl-2,3-dihydro-1,3-benzothiazol-5-yl]oxy}methyl)quinoline) |
|
134
|
330
|
4lm0A |
Crystal structure of pde10a2 with fragment zt448 |
|
136
|
330
|
4llxA |
Crystal structure of pde10a2 with fragment zt434 |
|
126
|
328
|
4mshA |
Crystal structure of pde10a2 with fragment zt0143 ((2s)-4-chloro-2,3-dihydro-1,3-benzothiazol-2-amine) |
|
136
|
330
|
4mrwA |
Crystal structure of pde10a2 with fragment zt0120 (7-chloroquinolin-4-ol) |
|
138
|
330
|
4lm4A |
Crystal structure of pde10a2 with fragment zt902 |
|
134
|
332
|
4lm1A |
Crystal structure of pde10a2 with fragment zt450 |
|
134
|
330
|
4msnA |
Crystal structure of pde10a2 with fragment zt0451 (8-nitroquinoline) |
|
135
|
330
|
4ms0A |
Crystal structure of pde10a2 with fragment zt0443 (6-chloropyrimidine-2,4-diamine) |
|
136
|
330
|
4llkA |
Crystal structure of pde10a2 with fragment zt217 |
|
136
|
331
|
4lm3A |
Crystal structure of pde10a2 with fragment zt464 |
|
132
|
328
|
4mscA |
Crystal structure of pde10a2 with fragment zt1595 (2-[(quinolin-7-yloxy)methyl]quinoline) |
|
136
|
330
|
4msaA |
Crystal structure of pde10a2 with fragment zt0449 (5-nitro-1h-benzimidazole) |
|
118
|
326
|
4md6A |
Crystal structure of pde5 in complex with inhibitor 5r |
|
141
|
324
|
4kp6A |
Crystal structure of human phosphodiesterase 4b (pde4b) in complex with a [1,3,5]triazine derivative |
|
134
|
333
|
4i15A |
Crystal structure of tbrpdeb1 |
|
120
|
324
|
4i9zA |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
|
120
|
324
|
4ia0A |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
|
139
|
340
|
4jibA |
Crystal structure of of pde2-inhibitor complex |
|
129
|
318
|
4hf4A |
Crystal structure of pde10a with a biaryl ether inhibitor (1-(1-(3-(4-(benzo[d]thiazol-2-ylamino)phenoxy)pyrazin-2-yl)piperidin-4-yl)ethanol) |
|
130
|
318
|
4heuA |
Crystal structure of pde10a with a biaryl ether inhibitor ((1-(3-(4-((1h-benzo[d]imidazol-2-yl)amino)phenoxy)pyridin-2-yl)piperidin-4-yl)methanol) |
|
133
|
326
|
4gh6A |
Crystal structure of the pde9a catalytic domain in complex with inhibitor 28 |
|
124
|
322
|
4g2wA |
Crystal structure of pde5a in complex with its inhibitor |
|
119
|
325
|
4g2yA |
Crystal structure of pde5a complexed with its inhibitor |
|
137
|
328
|
4g2lA |
Human pde9 in complex with selective compound |
|
128
|
328
|
4g2jA |
Human pde9 in complex with selective compound |
|
130
|
322
|
4fcbA |
Potent and selective phosphodiesterase 10a inhibitors |
|
132
|
322
|
4fcdA |
Potent and selective phosphodiesterase 10a inhibitors |
|
127
|
305
|
3qpnA |
Structure of pde10-inhibitor complex |
|
130
|
305
|
3qpoA |
Structure of pde10-inhibitor complex |
|
138
|
325
|
3qi4A |
Crystal structure of pde9a(q453e) in complex with ibmx |
|
126
|
305
|
3qppA |
Structure of pde10-inhibitor complex |
|
137
|
325
|
3qi3A |
Crystal structure of pde9a(q453e) in complex with inhibitor bay73-6691 |
|
138
|
335
|
3o56A |
Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor |
|
137
|
323
|
3o0jA |
Pde4b in complex with ligand an2898 |
|
142
|
336
|
3o57A |
Catalytic domain of human phosphodiesterase 4b2b in complex with a 5-heterocycle pyrazolopyridine inhibitor |
|
131
|
326
|
3n3zA |
Crystal structure of pde9a (e406a) mutant in complex with ibmx |
|
139
|
345
|
3ly2A |
Catalytic domain of human phosphodiesterase 4b in complex with a coumarin-based inhibitor |
|
126
|
308
|
3lxgA |
Crystal structure of rat phosphodiesterase 10a in complex with ligand web-3 |
|
128
|
347
|
3kktA |
Crystal structure of human pde4b with 5-[3-[(1s,2s,4r)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyp henyl]tetrahydro-2(1h)-pyrimidinone reveals ordering of the c-terminal helix residues 502-509. |
|
133
|
324
|
3jwqA |
Crystal structure of chimeric pde5/pde6 catalytic domain complexed with sildenafil |
|
134
|
320
|
3k3hA |
Crystal structure of the pde9a catalytic domain in complex with (s)-bay73-6691 |
|
136
|
329
|
3k4sA |
The structure of the catalytic domain of human pde4d with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone |
|
131
|
323
|
3jwrA |
Crystal structure of chimeric pde5/pde6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (ibmx) and pde6 gamma-subunit inhibitory peptide 70-87. |
|
134
|
319
|
3k3eA |
Crystal structure of the pde9a catalytic domain in complex with (r)-bay73-6691 |
|
134
|
328
|
3jswA |
Human pde9 in complex with selective inhibitor |
|
128
|
328
|
3jsiA |
Human phosphodiesterase 9 in complex with inhibitor |
