|
108
|
427
|
5j2mB |
Hiv-1 reverse transcriptase in complex with dna and efda-triphosphate, a translocation-defective rt inhibitor |
|
110
|
425
|
5j2pB |
Hiv-1 reverse transcriptase in complex with dna that has incorporated efda-mp at the p-(post-translocation) site and a second efda-mp at the n-(pre-translocation) site |
|
110
|
428
|
5j1eB |
Crystal structure of a hydroxypyridone carboxylic acid active-site rnase h inhibitor in complex with hiv reverse transcriptase |
|
133
|
550
|
5j1eA |
Crystal structure of a hydroxypyridone carboxylic acid active-site rnase h inhibitor in complex with hiv reverse transcriptase |
|
108
|
424
|
5hbmB |
Crystal structure of a dihydroxycoumarin rnase h active-site inhibitor in complex with hiv-1 reverse transcriptase |
|
111
|
424
|
5c25B |
Crystal structure of hiv-1 reverse transcriptase in complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (jlj639), a non-nucleoside inhibitor |
|
114
|
425
|
4r5pB |
Crystal structure of hiv-1 reverse transcriptase (rt) with dna and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor |
|
131
|
547
|
5c42A |
Crystal structure of hiv-1 reverse transcriptase (k101p) variant in complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor |
|
120
|
412
|
5c24B |
Crystal structure of hiv-1 reverse transcriptase in complex with 7-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-6,8-dimethylindolizine-2-carbonitrile (jlj605), a non-nucleoside inhibitor |
|
147
|
554
|
5c25A |
Crystal structure of hiv-1 reverse transcriptase in complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (jlj639), a non-nucleoside inhibitor |
|
100
|
424
|
5c42B |
Crystal structure of hiv-1 reverse transcriptase (k101p) variant in complex with 8-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)indolizine-2-carbonitrile (jlj555), a non-nucleoside inhibitor |
|
114
|
427
|
4zhrB |
Structure of hiv-1 rt q151m mutant |
|
143
|
553
|
4zhrA |
Structure of hiv-1 rt q151m mutant |
|
115
|
427
|
4dg1B |
Crystal structure of hiv-1 reverse transcriptase (rt) with polymorphism mutation k172a and k173a |
|
149
|
549
|
4dg1A |
Crystal structure of hiv-1 reverse transcriptase (rt) with polymorphism mutation k172a and k173a |
|
106
|
424
|
3tamB |
Crystal structure of hiv-1 reverse transcriptase (k103n mutant) in complex with inhibitor m06 |
|
160
|
557
|
3tamA |
Crystal structure of hiv-1 reverse transcriptase (k103n mutant) in complex with inhibitor m06 |
|
155
|
558
|
3t1aA |
Crystal structure of hiv-1 reverse transcriptase (k103n mutant) in complex with inhibitor m05 |
|
155
|
558
|
3t19A |
Crystal structure of hiv-1 reverse transcriptase (wild type) in complex with inhibitor m05 |
|
106
|
427
|
5j2nB |
Hiv-1 reverse transcriptase in complex with dna that has incorporated efda-mp at the p-(post-translocation) site and dtmp at the n-(pre-translocation) site |
|
151
|
537
|
5c24A |
Crystal structure of hiv-1 reverse transcriptase in complex with 7-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-6,8-dimethylindolizine-2-carbonitrile (jlj605), a non-nucleoside inhibitor |
|
156
|
543
|
5k14A |
Hiv-1 reverse transcriptase in complex with a 2,6-difluorophenyl dapy analog |
|
111
|
424
|
5k14B |
Hiv-1 reverse transcriptase in complex with a 2,6-difluorophenyl dapy analog |
|
161
|
554
|
5hbmA |
Crystal structure of a dihydroxycoumarin rnase h active-site inhibitor in complex with hiv-1 reverse transcriptase |
|
106
|
422
|
5fdlB |
Crystal structure of k103n/y181c mutant hiv-1 reverse transcriptase (rt) in complex with idx899 |
|
144
|
554
|
5fdlA |
Crystal structure of k103n/y181c mutant hiv-1 reverse transcriptase (rt) in complex with idx899 |
|
117
|
424
|
5cyqB |
Hiv-1 reverse transcriptase complexed with 4-bromopyrazole |
|
111
|
424
|
5cymB |
Hiv-1 reverse transcriptase complexed with 4-iodopyrazole |
|
154
|
548
|
5cyqA |
Hiv-1 reverse transcriptase complexed with 4-bromopyrazole |
|
193
|
596
|
5cqgA |
Structure of tribolium telomerase in complex with the highly specific inhibitor bibr1532 |
|
151
|
556
|
5cymA |
Hiv-1 reverse transcriptase complexed with 4-iodopyrazole |
|
140
|
547
|
4we1A |
Crystal structure of hiv-1 reverse transcriptase in complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-2-naphthonitrile (jlj600) |
|
106
|
425
|
4we1B |
Crystal structure of hiv-1 reverse transcriptase in complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-2-naphthonitrile (jlj600) |
|
138
|
554
|
4rw7A |
Crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor |
|
146
|
554
|
4rw6A |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor |
|
136
|
548
|
4rw8A |
Crystal structure of hiv-1 reverse transcriptase in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor' |
|
138
|
554
|
4rw9A |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor |
|
102
|
424
|
4rw7B |
Crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor |
|
110
|
424
|
4rw4B |
Crystal structure of hiv-1 reverse transcriptase (k103n,y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor |
|
110
|
427
|
4rw8B |
Crystal structure of hiv-1 reverse transcriptase in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor' |
|
145
|
554
|
4rw4A |
Crystal structure of hiv-1 reverse transcriptase (k103n,y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor |
|
109
|
424
|
4rw9B |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj532), a non-nucleoside inhibitor |
|
111
|
424
|
4rw6B |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with (e)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj494), a non-nucleoside inhibitor |
|
140
|
552
|
4o44A |
Crystal structure of hiv-1 reverse transcriptase in complex with 4-((4-(mesitylamino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino)benzonitrile (jlj529), a non-nucleoside inhibitor |
|
108
|
425
|
4ncgB |
Discovery of doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant hiv viruses |
|
99
|
427
|
4o44B |
Crystal structure of hiv-1 reverse transcriptase in complex with 4-((4-(mesitylamino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino)benzonitrile (jlj529), a non-nucleoside inhibitor |
|
100
|
428
|
4o4gB |
Crystal structure of hiv-1 reverse transcriptase in complex with 4-((4-(mesitylamino)-1,3,5-triazin-2-yl)amino)benzonitrile (jlj527), a non-nucleoside inhibitor |
|
165
|
556
|
4ncgA |
Discovery of doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant hiv viruses |
|
134
|
554
|
4o4gA |
Crystal structure of hiv-1 reverse transcriptase in complex with 4-((4-(mesitylamino)-1,3,5-triazin-2-yl)amino)benzonitrile (jlj527), a non-nucleoside inhibitor |
|
133
|
548
|
4lslA |
Crystal structure of hiv-1 reverse transcriptase in complex with (e)-3-(3-(4-chloro-2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (jlj476), a non-nucleoside inhibitor |
