|
90
|
305
|
8pqeA |
C-kit kinase domain in complex with avapritinib derivative 11 |
|
110
|
349
|
8pqjA |
Pdgfra wild-type kinase domain |
|
97
|
305
|
8pqaA |
C-kit kinase domain in complex with avapritinib derivative 4 |
|
91
|
345
|
8pqhA |
Pdgfra t674i mutant kinase domain in complex with avapritinib |
|
98
|
306
|
8pq9A |
C-kit kinase domain in complex with avapritinib |
|
98
|
305
|
8pqbA |
C-kit kinase domain in complex with avapritinib derivative 8 |
|
95
|
306
|
8pqgA |
C-kit t670i mutated kinase domain in complex with avapritinib |
|
91
|
331
|
8pqiA |
Pdgfra t674i mutant kinase domain in complex with avapritinib derivative 9 |
|
99
|
306
|
8pqfA |
C-kit kinase domain in complex with avapritinib derivative 12 |
|
195
|
983
|
8clsA |
Drosophila melanogaster insulin receptor ectodomain in complex with dilp5 |
|
90
|
326
|
8wd4A |
Egfr(l858r/t790/c797s) in complex with compound 5j |
|
111
|
897
|
6pyhA |
Cryo-em structure of full-length igf1r-igf1 complex. only the extracellular region of the complex is resolved. |
|
87
|
307
|
6iuoA |
Crystal structure of fgfr4 kinase domain in complex with a covalent inhibitor |
|
81
|
296
|
7ozyAAA |
Fgfr2 kinase domain (residues 461-763) in complex with 38. |
|
86
|
302
|
7ozdAAA |
Fgfr1 kinase domain (residues 458-765) with mutations c488a, c584s in complex with 34. |
|
83
|
301
|
7ozfAAA |
Fgfr1 kinase domain (residues 458-765) with mutations c488a, c584s in complex with 19. |
|
88
|
346
|
7n00A |
Anaplastic lymphoma kinase (alk) extracellular fragment of ligand binding region 648-1025 in complex with aug-alpha |
|
130
|
500
|
7lfrA |
Crystal structure of the epidermal growth factor receptor extracellular region with r84k mutation in complex with epiregulin crystallized with spermine |
|
104
|
614
|
7sydA |
Cryo-em structure of the extracellular module of the full-length egfr bound to egf "tips-juxtaposed" conformation |
|
91
|
353
|
7mzwA |
Anaplastic lymphoma kinase (alk) extracellular ligand binding region 673-1025 |
|
177
|
606
|
7mn8B |
Structure of the her2/her3/nrg1b heterodimer extracellular domain bound to trastuzumab fab |
|
122
|
500
|
7lfsA |
Crystal structure of the epidermal growth factor receptor extracellular region with a265v mutation in complex with epiregulin |
|
72
|
347
|
7lirA |
Structure of the invertebrate alk grd |
|
92
|
428
|
7ls0A |
Structure of the human alk grd bound to aug |
|
90
|
306
|
7lrzA |
Structure of the human alk grd |
|
87
|
300
|
7wctA |
Crystal structure of fgfr4 kinase domain with 7v |
|
89
|
300
|
7wcxA |
Crystal structure of fgfr4(v550m) kinase domain with 7v |
|
21
|
131
|
7bheB |
Darpin_d5/her3 domain 4 complex, monoclinic crystals |
|
80
|
300
|
7vjlA |
The crystal structure of fgfr4 kinase domain in complex with n-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-(2,2,2-trifluoroacetyl)-3,4-dihydro-1,8-naphthyridine-1(2h)-carboxamide |
|
83
|
297
|
7v29A |
Crystal structure of fgfr4 with a dual-warhead covalent inhhibitor |
|
84
|
309
|
7tvdA |
Crystal structure of the kinase domain of egfr exon-19 (del-747-749) mutant |
|
109
|
614
|
7syeA |
Cryo-em structure of the extracellular module of the full-length egfr bound to egf. "tips-separated" conformation |
|
91
|
614
|
7sz5A |
Cryo-em structure of the extracellular module of the full-length egfr bound to tgf-alpha "tips-separated" conformation |
|
96
|
614
|
7sz7A |
Cryo-em structure of the extracellular module of the full-length egfr bound to tgf-alpha. "tips-juxtaposed" conformation |
|
107
|
614
|
7sz0A |
Cryo-em structure of the extracellular module of the full-length egfr l834r bound to egf. "tips-juxtaposed" conformation |
|
86
|
614
|
7sz1A |
Cryo-em structure of the extracellular module of the full-length egfr l834r bound to egf. "tips-separated" conformation |
|
154
|
905
|
7stjA |
Full-length insulin receptor bound with unsaturated insulin wt (2 insulins bound) asymmetric conformation (conformation 1) |
|
147
|
910
|
7sthA |
Full-length insulin receptor bound with unsaturated insulin wt (2 insulin bound) symmetric conformation |
|
163
|
905
|
7stiA |
Full-length insulin receptor bound with unsaturated insulin wt (1 insulin bound) asymmetric conformation |
|
154
|
905
|
7stkA |
Full-length insulin receptor bound with unsaturated insulin wt (2 insulins bound) asymmetric conformation (conformation 2) |
|
154
|
905
|
7sl2A |
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (a-l13r) -- asymmetric conformation |
|
83
|
302
|
7ozbAAA |
Fgfr1 kinase domain (residues 458-765) with mutations c488a, c584s in complex with 38. |
|
158
|
905
|
7sl4A |
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (b-l17r) -- asymmetric conformation |
|
159
|
909
|
7sl1A |
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (a-v3e) |
|
167
|
910
|
7sl7A |
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (a-v3e) and site 2 binding deficient mutant insulin (a-l13r) |
|
150
|
910
|
7sl3A |
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (a-l13r) -- symmetric conformation |
|
160
|
910
|
7sl6A |
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (b-l17r) -- symmetric conformation |
|
71
|
308
|
7runA |
Crystal structure of phosphorylated ret tyrosine kinase domain complexed with a pyrrolo[2,3-d]pyrimidine inhibitor. |
|
86
|
301
|
7mfcA |
Crystal structure of csf1r in complex with vimseltinib |
|
180
|
603
|
7mn8A |
Structure of the her2/her3/nrg1b heterodimer extracellular domain bound to trastuzumab fab |
