|
90
|
295
|
3ib8A |
Crystal structure of full length rv0805 in complex with 5'-amp |
|
139
|
360
|
3hmvA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a tetrahydrobenzothiophene inhibitor |
|
131
|
324
|
3hc8A |
Investigation of aminopyridiopyrazinones as pde5 inhibitors: evaluation of modifications to the central ring system. |
|
129
|
323
|
3hdzA |
Identification, synthesis, and sar of amino substituted pyrido[3,2b]pryaziones as potent and selective pde5 inhibitors |
|
139
|
336
|
3gwtA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a quinoline inhibitor |
|
139
|
329
|
3g4lA |
Crystal structure of human phosphodiesterase 4d with roflumilast |
|
139
|
335
|
3g58A |
Crystal structure of human phosphodiesterase 4d with d155988/pmnpq |
|
133
|
318
|
3g3nA |
Pde7a catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one |
|
142
|
386
|
3g4gA |
Crystal structure of human phosphodiesterase 4d with regulatory domain and d155871 |
|
150
|
407
|
3g45A |
Crystal structure of human phosphodiesterase 4b with regulatory domain and d155988 |
|
139
|
331
|
3g4iA |
Crystal structure of human phosphodiesterase 4d with d155871 |
|
141
|
330
|
3g4kA |
Crystal structure of human phosphodiesterase 4d with rolipram |
|
137
|
335
|
3frgA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a quinoline inhibitor |
|
136
|
338
|
3ecmA |
Crystal structure of the unliganded pde8a catalytic domain |
|
135
|
338
|
3ecnA |
Crystal structure of pde8a catalytic domain in complex with ibmx |
|
139
|
336
|
3d3pA |
Crystal structure of pde4b catalytic domain in complex with a pyrazolopyridine inhibitor |
|
141
|
334
|
2qykA |
Crystal structure of pde4a10 in complex with inhibitor npv |
|
135
|
335
|
2qylA |
Crystal structure of pde4b2b in complex with inhibitor npv |
|
114
|
329
|
2qymA |
Crystal structure of unliganded pde4c2 |
|
140
|
326
|
2qynA |
Crystal structure of pde4d2 in complex with inhibitor npv |
|
135
|
327
|
2pw3A |
Structure of the pde4d-camp complex |
|
69
|
256
|
2hypA |
Crystal structure of rv0805 d66a mutant |
|
70
|
256
|
2hyoA |
Crystal structure of rv0805 n97a mutant |
|
66
|
256
|
2hy1A |
Crystal structure of rv0805 |
|
140
|
334
|
2fm0A |
Crystal structure of pde4d in complex with l-869298 |
|
135
|
334
|
2fm5A |
Crystal structure of pde4d2 in complex with inhibitor l-869299 |
|
133
|
323
|
2chmA |
Crystal structure of n2 substituted pyrazolo pyrimidinones - a flipped binding mode in pde5 |
|
141
|
317
|
1zklA |
Multiple determinants for inhibitor selectivity of cyclic nucleotide phosphodiesterases |
|
138
|
334
|
1zknA |
Structure of pde4d2-ibmx |
|
139
|
326
|
1y2dA |
Catalytic domain of human phosphodiesterase 4d in complex with 1-(4-methoxy-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
140
|
326
|
1y2cA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1-phenyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
134
|
326
|
1y2eA |
Catalytic domain of human phosphodiesterase 4d in complex with 1-(4-amino-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
140
|
326
|
1y2kA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1-(3-nitro-phenyl)-1h-pyrazole-4-carboxylic acid ethyl ester |
|
138
|
326
|
1y2bA |
Catalytic domain of human phosphodiesterase 4d in complex with 3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
124
|
323
|
1y2jA |
Catalytic domain of human phosphodiesterase 4b in complex with 3,5-dimethyl-1-(3-nitro-phenyl)-1h-pyrazole-4-carboxylic acid ethyl ester |
|
121
|
323
|
1y2hA |
Catalytic domain of human phosphodiesterase 4b in complex with 1-(2-chloro-phenyl)-3,5-dimethyl-1h-pyrazole-4-carboxylic acid ethyl ester |
|
139
|
326
|
1xonA |
Catalytic domain of human phosphodiesterase 4d in complex with piclamilast |
|
128
|
323
|
1xotA |
Catalytic domain of human phosphodiesterase 4b in complex with vardenafil |
|
136
|
324
|
1xorA |
Catalytic domain of human phosphodiesterase 4d in complex with zardaverine |
|
126
|
323
|
1xmuB |
Catalytic domain of human phosphodiesterase 4b in complex with roflumilast |
|
127
|
323
|
1xlxA |
Catalytic domain of human phosphodiesterase 4b in complex with cilomilast |
|
136
|
326
|
1xomA |
Catalytic domain of human phosphodiesterase 4d in complex with cilomilast |
|
127
|
323
|
1xn0A |
Catalytic domain of human phosphodiesterase 4b in complex with (r,s)-rolipram |
|
129
|
323
|
1xm4B |
Catalytic domain of human phosphodiesterase 4b in complex with piclamilast |
|
130
|
323
|
1xlzA |
Catalytic domain of human phosphodiesterase 4b in complex with filaminast |
|
138
|
326
|
1xoqA |
Catalytic domain of human phosphodiesterase 4d in complex with roflumilast |
|
132
|
323
|
1xm4A |
Catalytic domain of human phosphodiesterase 4b in complex with piclamilast |
|
123
|
323
|
1xmyB |
Catalytic domain of human phosphodiesterase 4b in complex with (r)-rolipram |
|
132
|
331
|
1xmuA |
Catalytic domain of human phosphodiesterase 4b in complex with roflumilast |
|
132
|
351
|
1xm6A |
Catalytic domain of human phosphodiesterase 4b in complex with (r)-mesopram |
