|
12
|
58
|
5pb2A |
Crystal structure of factor viia in complex with 2-phenyl-4-(1h-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-3-ol |
|
60
|
254
|
5paoC |
Crystal structure of factor viia in complex with (2s)-2,3-dihydroxy-n-[[3-[5-hydroxy-4-(1h-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide;hydrobromide |
|
12
|
57
|
5pacA |
Human factor viia in complex with 5-hydroxy-n-(4-oxo-3h-quinazolin-6-yl)-1-[3-[(phenylcarbamoylamino)methyl]phenyl]pyrazole-4-carboxamide at 1.50a |
|
64
|
254
|
5pajB |
Crystal structure of factor viia in complex with 1-(1-aminoisoquinolin-6-yl)-3-benzylurea |
|
12
|
55
|
4zxyL |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione |
|
58
|
254
|
4zxxH |
Factor viia in complex with the inhibitor n-{3-[(2r)-1-{(2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide |
|
13
|
55
|
5i46L |
Factor viia in complex with the inhibitor (2r,15r)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-hydroxy-4,15,17-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione |
|
59
|
254
|
4zxyH |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione |
|
11
|
55
|
4zxxL |
Factor viia in complex with the inhibitor n-{3-[(2r)-1-{(2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}acetamide |
|
64
|
249
|
4ylqH |
Crystal structure of a fviia-trypsin chimera (ft) in complex with soluble tissue factor |
|
13
|
55
|
4yt6L |
Factor viia in complex with the inhibitor 4-{[(r)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1h-imidazol-2-yl)methyl]amino}benzenecarboximidamide |
|
30
|
143
|
4ylqL |
Crystal structure of a fviia-trypsin chimera (ft) in complex with soluble tissue factor |
|
61
|
254
|
4yt6H |
Factor viia in complex with the inhibitor 4-{[(r)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1h-imidazol-2-yl)methyl]amino}benzenecarboximidamide |
|
12
|
55
|
4x8tL |
Factor viia in complex with the inhibitor 7-chloro-3,4-dihydroisoquinolin-1(2h)-one |
|
61
|
254
|
4x8sH |
Factor viia in complex with the inhibitor 4-bromo-2-methoxyphenol |
|
13
|
55
|
4x8sL |
Factor viia in complex with the inhibitor 4-bromo-2-methoxyphenol |
|
58
|
254
|
4x8vH |
Factor viia in complex with the inhibitor (methyl {3-[(2r)-1-{(2r)-2-(3,4-dimethoxyphenyl)-2-[(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]acetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}carbamate) |
|
12
|
55
|
4x8vL |
Factor viia in complex with the inhibitor (methyl {3-[(2r)-1-{(2r)-2-(3,4-dimethoxyphenyl)-2-[(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]acetyl}pyrrolidin-2-yl]-4-(propan-2-ylsulfonyl)phenyl}carbamate) |
|
59
|
254
|
4x8tH |
Factor viia in complex with the inhibitor 7-chloro-3,4-dihydroisoquinolin-1(2h)-one |
|
10
|
55
|
4x8uL |
Factor viia in complex with the inhibitor 5-chloro-1h-indole-2-carboxylic acid |
|
59
|
254
|
4x8uH |
Factor viia in complex with the inhibitor 5-chloro-1h-indole-2-carboxylic acid |
|
60
|
254
|
4ng9H |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(3-sulfamoylbenzyl)ethanamide |
|
12
|
55
|
4na9L |
Factor viia in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid |
|
13
|
55
|
4ngaL |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-[2-(propan-2-ylsulfonyl)benzyl]ethanamide |
|
12
|
55
|
4ng9L |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(3-sulfamoylbenzyl)ethanamide |
|
60
|
254
|
4na9H |
Factor viia in complex with the inhibitor 3'-amino-5'-[(2s,4r)-6-carbamimidoyl-4-phenyl-1,2,3,4-tetrahydroquinolin-2-yl]biphenyl-2-carboxylic acid |
|
59
|
254
|
4ngaH |
Factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-[2-(propan-2-ylsulfonyl)benzyl]ethanamide |
|
62
|
254
|
4jzdH |
Structure of factor viia in complex with the inhibitor 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
13
|
55
|
4jzdL |
Structure of factor viia in complex with the inhibitor 2-{2-[(4-carbamimidoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
62
|
254
|
4jzeH |
Structure of factor viia in complex with the inhibitor 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
11
|
55
|
4jzeL |
Structure of factor viia in complex with the inhibitor 2-{2-[(1-aminoisoquinolin-6-yl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
12
|
55
|
4ishL |
Structure of factor viia in complex with the inhibitor bms-593214 also known as 2'-[(6r,6ar,11br)-2-carbamimidoyl-6,6a,7,11b-tetrahydro-5h-indeno[2,1-c]quinolin-6-yl]-5'-hydroxy-4'-methoxybiphenyl-4-carboxylic acid |
|
12
|
55
|
4isiL |
Structure of factor viia in complex with the inhibitor (6s)-n-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide |
|
59
|
254
|
4ishH |
Structure of factor viia in complex with the inhibitor bms-593214 also known as 2'-[(6r,6ar,11br)-2-carbamimidoyl-6,6a,7,11b-tetrahydro-5h-indeno[2,1-c]quinolin-6-yl]-5'-hydroxy-4'-methoxybiphenyl-4-carboxylic acid |
|
59
|
254
|
4jyuH |
Structure of factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(phenylsulfonyl)ethanamide |
|
12
|
55
|
4jyuL |
Structure of factor viia in complex with the inhibitor (2r)-2-[(1-aminoisoquinolin-6-yl)amino]-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-n-(phenylsulfonyl)ethanamide |
|
57
|
254
|
4iblH |
Rubidium sites in blood coagulation factor viia |
|
58
|
254
|
4jyvH |
Structure of factor viia in complex with the inhibitor (2r)-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-2-(isoquinolin-6-ylamino)-n-[(3-sulfamoylphenyl)sulfonyl]ethanamide |
|
60
|
254
|
4isiH |
Structure of factor viia in complex with the inhibitor (6s)-n-(4-carbamimidoylbenzyl)-1-chloro-3-(cyclobutylamino)-8,8-diethyl-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide |
|
62
|
254
|
4jzfH |
Structure of factor viia in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
31
|
140
|
4iblL |
Rubidium sites in blood coagulation factor viia |
|
12
|
55
|
4jzfL |
Structure of factor viia in complex with the inhibitor 2-{2-[(3-carbamoylphenyl)carbamoyl]-6-methoxypyridin-3-yl}-5-{[(2s)-1-hydroxy-3,3-dimethylbutan-2-yl]carbamoyl}benzoic acid |
|
14
|
55
|
4jyvL |
Structure of factor viia in complex with the inhibitor (2r)-2-[3-ethoxy-4-(propan-2-yloxy)phenyl]-2-(isoquinolin-6-ylamino)-n-[(3-sulfamoylphenyl)sulfonyl]ethanamide |
|
56
|
254
|
3elaH |
Crystal structure of active site inhibited coagulation factor viia mutant in complex with soluble tissue factor |
|
18
|
95
|
3elaL |
Crystal structure of active site inhibited coagulation factor viia mutant in complex with soluble tissue factor |
|
30
|
142
|
2zwlL |
Human factor viia-tissue factor complexed with highly selective peptide inhibitor |
|
56
|
254
|
2zzuH |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-5-(3-carboxybenzyloxy)-trp-gln-p-aminobenzamidine |
|
31
|
142
|
2zp0L |
Human factor viia-tissue factor complexed with benzylsulfonamide-d-ile-gln-p-aminobenzamidine |
|
54
|
254
|
2zp0H |
Human factor viia-tissue factor complexed with benzylsulfonamide-d-ile-gln-p-aminobenzamidine |
|
57
|
254
|
2zwlH |
Human factor viia-tissue factor complexed with highly selective peptide inhibitor |
