205
|
563
|
3udlA |
3-heterocyclyl quinolone bound to hcv ns5b |
207
|
563
|
3u4rA |
Novel hcv ns5b polymerase inhibitors: discovery of indole c2 acyl sulfonamides |
201
|
568
|
3uphA |
Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as hcv ns5b polymerase inhibitors |
204
|
568
|
3tyvA |
Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase |
209
|
568
|
3tyqA |
Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase |
53
|
192
|
3su4A |
Crystal structure of ns3/4a protease variant r155k in complex with vaniprevir |
195
|
563
|
3skhA |
I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles |
204
|
568
|
3skaA |
I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles |
197
|
568
|
3skeA |
I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles |
139
|
445
|
3rvbA |
The structure of hcv ns3 helicase (heli-80) bound with inhibitor itmn-3479 |
49
|
199
|
3rc4A |
Molecular mechanisms of viral and host-cell substrate recognition by hcv ns3/4a protease |
48
|
198
|
3rc5A |
Molecular mechanisms of viral and host-cell substrate recognition by hcv ns3/4a protease |
0
|
12
|
1w3cC |
Crystal structure of the hepatitis c virus ns3 protease in complex with a peptidomimetic inhibitor |
1
|
9
|
6bzvI |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the gl precursor of the broadly neutralizing antibody 19b3 |
48
|
198
|
5vp9A |
Crystal structure of hcv ns3/4a protease in complex with am-07, an analogue of 5172-mcp1p3 |
196
|
573
|
5twnA |
Crystal structure of the hepatitis c virus ns5b rna- dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-n-methylfuro[2,3-b]pyridine-3-carboxamide |
190
|
564
|
5triA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 3-[(4-chlorophenyl)methoxy]-2-(1-oxo-1,3-dihydro-2h-isoindol-2-yl)benzoic acid |
211
|
563
|
5twmA |
Crystal structure of the hepatitis c virus genotype 2a strain jfh1 l30s ns5b rna-dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-n-methylfuro[2,3-b]pyridine-3-carboxamide |
187
|
573
|
5trjA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-{[2-(carboxymethoxy)benzene-1-carbonyl]amino}-3-[(4-chlorophenyl)methoxy]benzoic acid |
193
|
573
|
5trhA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-[(benzenecarbonyl)amino]-3-[(4-chlorophenyl)methoxy]benzoic acid |
196
|
573
|
5trkA |
Crystal structure of the hepatitis c virus ns5b rna- dependent rna polymerase in complex with n-{3-[(benzenecarbonyl)amino]-4-[(4-chlorophenyl)methoxy]benzene-1-carbonyl}glycine |
193
|
573
|
5pznA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-n-methyl-1-benzofuran-3-carboxamide |
192
|
573
|
5pzmA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 3-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-5-yl]benzoic acid |
188
|
563
|
5pzkA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-(4-fluorophenyl)-n-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide |
191
|
573
|
5pzpA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 4-fluoro-2-(4-fluorophenyl)-n-methyl-5-(2-methyl-5-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide (bms-929075) |
195
|
573
|
5pzlA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-({3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda~6~,2,4-benzothiadiazin-7-yl}oxy)acetamide |
193
|
573
|
5pzoA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase c316n in complex with 2-(4-fluorophenyl)-n-methyl-5-[3-({2-methyl-1-oxo-1-[(1,3,4-thiadiazol-2-yl)amino]propan-2-yl}carbamoyl)phenyl]-1-benzofuran-3-carboxamide |
1
|
9
|
5npiD |
Structure of the hepatitis c virus strain j4 glycoprotein e2 antigenic region 532-540 bound to the single chain variable fragment of the non-neutralizing antibody dao5 |
1
|
9
|
5nphA |
Structure of the hepatitis c virus strain j4 glycoprotein e2 antigenic region 532-540 bound to the fab fragment of the non-neutralizing antibody dao5 |
1
|
9
|
5npjD |
Structure of the hepatitis c virus strain jfh1 glycoprotein e2 antigenic region 532-540 bound to the single chain variable fragment of the non-neutralizing antibody dao5 |
1
|
12
|
4z0xC |
Structure of hepatitis c virus envelope glycoprotein e2 antigenic region 434-446 bound to the broadly neutralizing antibody hc26am |
202
|
645
|
5fpyA |
Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 5-bromo-1-methyl-1h-indole-2-carboxylic acid (at21457) in an alternate binding site. |
0
|
9
|
5fgcA |
Three dimensional structure of broadly neutralizing human anti - hepatitis c virus (hcv) glycoprotein e2 fab fragment hc33.8 |
202
|
645
|
5fpsA |
Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 3-aminobenzene-1,2-dicarboxylic acid (at1246) in an alternate binding site. |
199
|
645
|
5fptA |
Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 2-(1-methyl-1h-indol-3-yl)acetic acid (at3437) in an alternate binding site. |
150
|
437
|
5e4fA |
The spring alpha-helix coordinates multiple modes of hcv ns3 helicase action |
0
|
13
|
5eocP |
Crystal structure of fab c2 in complex with a cyclic variant of hepatitis c virus e2 epitope i |
207
|
563
|
5czbA |
Hcv ns5b in complex with ligand idx17119-5 |
1
|
13
|
4xvjA |
Structure of the hepatitis c virus envelope glycoprotein e2 antigenic 2 region 412-423 bound to the broadly neutralizing antibody hc33.1 |
151
|
445
|
4wxpA |
X-ray crystal structure of ns3 helicase from hcv with a bound fragment inhibitor at 2.08 a resolution |
203
|
544
|
4wt9A |
Apo crystal structure of hcv ns5b genotype 2a jfh-1 isolate with e86q e87q s15g c223h v321i and delta8 mutations |
196
|
565
|
4ry7A |
C-terminal mutant (d559e) of hcv/j4 rna polymerase |
186
|
566
|
4ry4A |
C-terminal mutant (y448f) of hcv/j4 rna polymerase |
200
|
565
|
4ry5A |
C-terminal mutant (w550n) of hcv/j4 rna polymerase |
208
|
566
|
4tn2A |
Ns5b in complex with lactam-thiophene carboxylic acids |
197
|
565
|
4ry6A |
C-terminal mutant (w550a) of hcv/j4 rna polymerase |
37
|
182
|
4u01A |
Hcv ns3/4a serine protease in complex with 6570 |
198
|
562
|
4oowA |
Hcv ns5b polymerase with a fragment of quercetagetin |
1
|
9
|
4q0xE |
Crystal structure of non-neutralizing antibody in complex with epitope ii of hcv e2 |
206
|
568
|
4mz4A |
Discovery of an irreversible hcv ns5b polymerase inhibitor |