Found 364 chains in Genus chains table. Displaying 101 - 150. Applied filters: Proteins

Search results query ec: 3.4.21.98

Total Genus Sequence Length pdb Title
205 563 3udlA 3-heterocyclyl quinolone bound to hcv ns5b
207 563 3u4rA Novel hcv ns5b polymerase inhibitors: discovery of indole c2 acyl sulfonamides
201 568 3uphA Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as hcv ns5b polymerase inhibitors
204 568 3tyvA Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase
209 568 3tyqA Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase
53 192 3su4A Crystal structure of ns3/4a protease variant r155k in complex with vaniprevir
195 563 3skhA I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles
204 568 3skaA I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles
197 568 3skeA I. novel hcv ns5b polymerase inhibitors: discovery of indole 2- carboxylic acids with c3-heterocycles
139 445 3rvbA The structure of hcv ns3 helicase (heli-80) bound with inhibitor itmn-3479
49 199 3rc4A Molecular mechanisms of viral and host-cell substrate recognition by hcv ns3/4a protease
48 198 3rc5A Molecular mechanisms of viral and host-cell substrate recognition by hcv ns3/4a protease
0 12 1w3cC Crystal structure of the hepatitis c virus ns3 protease in complex with a peptidomimetic inhibitor
1 9 6bzvI Structure of the hepatitis c virus envelope glycoprotein e2 antigenic region 412-423 bound to the gl precursor of the broadly neutralizing antibody 19b3
48 198 5vp9A Crystal structure of hcv ns3/4a protease in complex with am-07, an analogue of 5172-mcp1p3
196 573 5twnA Crystal structure of the hepatitis c virus ns5b rna- dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-n-methylfuro[2,3-b]pyridine-3-carboxamide
190 564 5triA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 3-[(4-chlorophenyl)methoxy]-2-(1-oxo-1,3-dihydro-2h-isoindol-2-yl)benzoic acid
211 563 5twmA Crystal structure of the hepatitis c virus genotype 2a strain jfh1 l30s ns5b rna-dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-n-methylfuro[2,3-b]pyridine-3-carboxamide
187 573 5trjA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-{[2-(carboxymethoxy)benzene-1-carbonyl]amino}-3-[(4-chlorophenyl)methoxy]benzoic acid
193 573 5trhA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-[(benzenecarbonyl)amino]-3-[(4-chlorophenyl)methoxy]benzoic acid
196 573 5trkA Crystal structure of the hepatitis c virus ns5b rna- dependent rna polymerase in complex with n-{3-[(benzenecarbonyl)amino]-4-[(4-chlorophenyl)methoxy]benzene-1-carbonyl}glycine
193 573 5pznA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-n-methyl-1-benzofuran-3-carboxamide
192 573 5pzmA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 3-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-5-yl]benzoic acid
188 563 5pzkA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-(4-fluorophenyl)-n-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide
191 573 5pzpA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 4-fluoro-2-(4-fluorophenyl)-n-methyl-5-(2-methyl-5-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide (bms-929075)
195 573 5pzlA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-({3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda~6~,2,4-benzothiadiazin-7-yl}oxy)acetamide
193 573 5pzoA Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase c316n in complex with 2-(4-fluorophenyl)-n-methyl-5-[3-({2-methyl-1-oxo-1-[(1,3,4-thiadiazol-2-yl)amino]propan-2-yl}carbamoyl)phenyl]-1-benzofuran-3-carboxamide
1 9 5npiD Structure of the hepatitis c virus strain j4 glycoprotein e2 antigenic region 532-540 bound to the single chain variable fragment of the non-neutralizing antibody dao5
1 9 5nphA Structure of the hepatitis c virus strain j4 glycoprotein e2 antigenic region 532-540 bound to the fab fragment of the non-neutralizing antibody dao5
1 9 5npjD Structure of the hepatitis c virus strain jfh1 glycoprotein e2 antigenic region 532-540 bound to the single chain variable fragment of the non-neutralizing antibody dao5
1 12 4z0xC Structure of hepatitis c virus envelope glycoprotein e2 antigenic region 434-446 bound to the broadly neutralizing antibody hc26am
202 645 5fpyA Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 5-bromo-1-methyl-1h-indole-2-carboxylic acid (at21457) in an alternate binding site.
0 9 5fgcA Three dimensional structure of broadly neutralizing human anti - hepatitis c virus (hcv) glycoprotein e2 fab fragment hc33.8
202 645 5fpsA Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 3-aminobenzene-1,2-dicarboxylic acid (at1246) in an alternate binding site.
199 645 5fptA Structure of hepatitis c virus (hcv) full-length ns3 complex with small-molecule ligand 2-(1-methyl-1h-indol-3-yl)acetic acid (at3437) in an alternate binding site.
150 437 5e4fA The spring alpha-helix coordinates multiple modes of hcv ns3 helicase action
0 13 5eocP Crystal structure of fab c2 in complex with a cyclic variant of hepatitis c virus e2 epitope i
207 563 5czbA Hcv ns5b in complex with ligand idx17119-5
1 13 4xvjA Structure of the hepatitis c virus envelope glycoprotein e2 antigenic 2 region 412-423 bound to the broadly neutralizing antibody hc33.1
151 445 4wxpA X-ray crystal structure of ns3 helicase from hcv with a bound fragment inhibitor at 2.08 a resolution
203 544 4wt9A Apo crystal structure of hcv ns5b genotype 2a jfh-1 isolate with e86q e87q s15g c223h v321i and delta8 mutations
196 565 4ry7A C-terminal mutant (d559e) of hcv/j4 rna polymerase
186 566 4ry4A C-terminal mutant (y448f) of hcv/j4 rna polymerase
200 565 4ry5A C-terminal mutant (w550n) of hcv/j4 rna polymerase
208 566 4tn2A Ns5b in complex with lactam-thiophene carboxylic acids
197 565 4ry6A C-terminal mutant (w550a) of hcv/j4 rna polymerase
37 182 4u01A Hcv ns3/4a serine protease in complex with 6570
198 562 4oowA Hcv ns5b polymerase with a fragment of quercetagetin
1 9 4q0xE Crystal structure of non-neutralizing antibody in complex with epitope ii of hcv e2
206 568 4mz4A Discovery of an irreversible hcv ns5b polymerase inhibitor