|
76
|
163
|
5ubtB |
Crystal structure of pi3k delta in complex with a 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4] triazin-4-amine deriviatine |
|
96
|
265
|
5ukjB |
The co-structure of n,n-dimethyl-4-[(6r)-6-methyl-5-(1h-pyrrolo[2,3- b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5- a]pyrazin-3-yl]benzenesulfonamide and a rationally designed pi3k-alpha mutant that mimics atr |
|
102
|
265
|
5ul1B |
The co-structure of 3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfonyl)phenyl)-n-phenylpyrazine-2-carboxamide and a rationally designed pi3k-alpha mutant that mimics atr |
|
95
|
267
|
5uk8B |
The co-structure of (r)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1h-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine and a rationally designed pi3k-alpha mutant that mimics atr |
|
274
|
1015
|
5t8fA |
P110delta/p85alpha with taselisib (gdc-0032) |
|
302
|
1083
|
5sxiA |
Crystal structure of pi3kalpha in complex with fragment 13 |
|
286
|
1081
|
5swpA |
Crystal structure of pi3kalpha in complex with fragments 6 and 24 |
|
309
|
1081
|
5sxdA |
Crystal structure of pi3kalpha in complex with fragment 22 |
|
240
|
916
|
5t8iA |
Pi3kdelta in complex with the inhibitor gs-9901 |
|
301
|
1079
|
5sxkA |
Crystal structure of pi3kalpha in complex with fragment 18 |
|
286
|
1085
|
5sxaA |
Crystal structure of pi3kalpha in complex with fragment 10 |
|
309
|
1079
|
5swgA |
Crystal structure of pi3kalpha in complex with fragments 5 and 21 |
|
291
|
1081
|
5sxeA |
Crystal structure of pi3kalpha in complex with fragments 19 and 28 |
|
303
|
1080
|
5sx9A |
Crystal structure of pi3kalpha in complex with fragment 14 |
|
293
|
1083
|
5sxbA |
Crystal structure of pi3kalpha in complex with fragment 23 |
|
261
|
919
|
5t2iA |
Mpi3kd in complex with 7k |
|
251
|
919
|
5t2gA |
Mpi3kd in complex with 7i |
|
260
|
919
|
5t27A |
Mpi3kd in complex with 5d |
|
284
|
1078
|
5sxjA |
Crystal structure of pi3kalpha in complex with fragment 29 |
|
282
|
1079
|
5sxcA |
Crystal structure of pi3kalpha in complex with fragment 8 |
|
259
|
919
|
5t2bA |
Mpi3kd in complex with 5e |
|
257
|
919
|
5t28A |
Mpi3kd in complex with 5k |
|
299
|
1078
|
5sxfA |
Crystal structure of pi3kalpha in complex with fragment 9 |
|
291
|
1081
|
5sx8A |
Crystal structure of pi3kalpha in complex with fragments 12 and 15 |
|
305
|
1079
|
5swrA |
Crystal structure of pi3kalpha in complex with fragments 20 and 26 |
|
304
|
1082
|
5swtA |
Crystal structure of pi3kalpha in complex with fragments 17 and 27 |
|
262
|
918
|
5t7fA |
Pi3kdelta in complex with the inhibitor gs-643624 |
|
75
|
169
|
5t8fB |
P110delta/p85alpha with taselisib (gdc-0032) |
|
254
|
919
|
5t2dA |
Mpi3kd in complex with 7j |
|
253
|
942
|
5t23A |
Pi3kg in complex with 5d |
|
278
|
1080
|
5sw8A |
Crystal structure of pi3kalpha in complex with fragments 7 and 11 |
|
240
|
919
|
5t2mA |
Mpi3kd in complex with 7m |
|
66
|
269
|
5sxbB |
Crystal structure of pi3kalpha in complex with fragment 23 |
|
75
|
272
|
5sxdB |
Crystal structure of pi3kalpha in complex with fragment 22 |
|
64
|
270
|
5sxcB |
Crystal structure of pi3kalpha in complex with fragment 8 |
|
74
|
270
|
5sxiB |
Crystal structure of pi3kalpha in complex with fragment 13 |
|
79
|
272
|
5swpB |
Crystal structure of pi3kalpha in complex with fragments 6 and 24 |
|
76
|
272
|
5swtB |
Crystal structure of pi3kalpha in complex with fragments 17 and 27 |
|
82
|
272
|
5swoB |
Crystal structure of pi3kalpha in complex with fragments 4 and 19 |
|
64
|
271
|
5sxjB |
Crystal structure of pi3kalpha in complex with fragment 29 |
|
75
|
272
|
5swrB |
Crystal structure of pi3kalpha in complex with fragments 20 and 26 |
|
69
|
258
|
5sxfB |
Crystal structure of pi3kalpha in complex with fragment 9 |
|
73
|
271
|
5sx9B |
Crystal structure of pi3kalpha in complex with fragment 14 |
|
71
|
271
|
5sxeB |
Crystal structure of pi3kalpha in complex with fragments 19 and 28 |
|
76
|
271
|
5sx8B |
Crystal structure of pi3kalpha in complex with fragments 12 and 15 |
|
56
|
270
|
5sw8B |
Crystal structure of pi3kalpha in complex with fragments 7 and 11 |
|
85
|
272
|
5swgB |
Crystal structure of pi3kalpha in complex with fragments 5 and 21 |
|
264
|
947
|
5oq4A |
Pqr309 - a potent, brain-penetrant, orally bioavailable, pan-class i pi3k/mtor inhibitor as clinical candidate in oncology |
|
240
|
919
|
5o83A |
Discovery of cdz173 (leniolisib), representing a structurally novel class of pi3k delta-selective inhibitors |
|
278
|
946
|
5kaeA |
Crystal structure of human pi3k-gamma in complex with quinoline-containing inhibitor 5g |
