134
|
338
|
3ituA |
Hpde2a catalytic domain complexed with ibmx |
117
|
314
|
3itmA |
Catalytic domain of hpde2a |
130
|
325
|
3iakA |
Crystal structure of human phosphodiesterase 4d (pde4d) with papaverine. |
211
|
678
|
3ibjA |
X-ray structure of pde2a |
131
|
335
|
3i8vA |
Crystal structure of human pde4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone |
138
|
358
|
3iadA |
Crystal structure of human phosphodiesterase 4d with bound allosteric modulator |
139
|
360
|
3hmvA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a tetrahydrobenzothiophene inhibitor |
128
|
305
|
3hqzA |
Discovery of novel inhibitors of pde10a |
128
|
305
|
3hqyA |
Discovery of novel inhibitors of pde10a |
130
|
303
|
3hqwA |
Discovery of novel inhibitors of pde10a |
128
|
305
|
3hr1A |
Discovery of novel inhibitors of pde10a |
129
|
323
|
3hdzA |
Identification, synthesis, and sar of amino substituted pyrido[3,2b]pryaziones as potent and selective pde5 inhibitors |
131
|
324
|
3hc8A |
Investigation of aminopyridiopyrazinones as pde5 inhibitors: evaluation of modifications to the central ring system. |
139
|
336
|
3gwtA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a quinoline inhibitor |
150
|
407
|
3g45A |
Crystal structure of human phosphodiesterase 4b with regulatory domain and d155988 |
139
|
329
|
3g4lA |
Crystal structure of human phosphodiesterase 4d with roflumilast |
139
|
335
|
3g58A |
Crystal structure of human phosphodiesterase 4d with d155988/pmnpq |
133
|
318
|
3g3nA |
Pde7a catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one |
142
|
386
|
3g4gA |
Crystal structure of human phosphodiesterase 4d with regulatory domain and d155871 |
137
|
335
|
3frgA |
Catalytic domain of human phosphodiesterase 4b2b in complex with a quinoline inhibitor |
139
|
331
|
3g4iA |
Crystal structure of human phosphodiesterase 4d with d155871 |
141
|
330
|
3g4kA |
Crystal structure of human phosphodiesterase 4d with rolipram |
136
|
338
|
3ecmA |
Crystal structure of the unliganded pde8a catalytic domain |
135
|
338
|
3ecnA |
Crystal structure of pde8a catalytic domain in complex with ibmx |
131
|
328
|
3dyqA |
Human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cgmp |
129
|
328
|
3dy8A |
Human phosphodiesterase 9 in complex with product 5'-gmp (e+p complex) |
131
|
324
|
3dysA |
Human phosphodiestrase-5'gmp complex (ep), produced by soaking with 20mm cgmp+20 mm mncl2+20 mm mgcl2 for 2 hours, and flash-cooled to liquid nitrogen temperature when substrate was still abudant. |
133
|
328
|
3dylA |
Human phosphdiesterase 9 substrate complex (es complex) |
132
|
328
|
3dynA |
Human phosphodiestrase 9 in complex with cgmp (zn inhibited) |
139
|
336
|
3d3pA |
Crystal structure of pde4b catalytic domain in complex with a pyrazolopyridine inhibitor |
127
|
326
|
3bjcA |
Crystal structure of the pde5a catalytic domain in complex with a novel inhibitor |
117
|
330
|
3b2rA |
Crystal structure of pde5a1 catalytic domain in complex with vardenafil |
128
|
326
|
2yy2A |
Crystal structure of the human phosphodiesterase 9a catalytic domain complexed with ibmx |
128
|
314
|
2y0jA |
Triazoloquinazolines as a novel class of phosphodiesterase 10a (pde10a) inhibitors, part 2, lead-optimisation. |
128
|
324
|
2weyA |
Human pde-papaverine complex obtained by ligand soaking of cross- linked protein crystals |
135
|
335
|
2qylA |
Crystal structure of pde4b2b in complex with inhibitor npv |
141
|
335
|
2r8qA |
Structure of lmjpdeb1 in complex with ibmx |
141
|
334
|
2qykA |
Crystal structure of pde4a10 in complex with inhibitor npv |
114
|
329
|
2qymA |
Crystal structure of unliganded pde4c2 |
140
|
326
|
2qynA |
Crystal structure of pde4d2 in complex with inhibitor npv |
135
|
327
|
2pw3A |
Structure of the pde4d-camp complex |
137
|
326
|
2ousA |
Crystal structure of pde10a2 mutant d674a |
126
|
304
|
2ovvA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
132
|
324
|
2ourA |
Crystal structure of pde10a2 mutant d674a in complex with camp |
125
|
307
|
2o8hA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
136
|
330
|
2ouyA |
Crystal structure of pde10a2 mutant d564a in complex with camp. |
132
|
326
|
2ouqA |
Crystal structure of pde10a2 in complex with gmp |
137
|
329
|
2ouuA |
Crystal structure of pde10a2 mutant d674a in complex with cgmp |
128
|
305
|
2ovyA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
132
|
326
|
2hd1A |
Crystal structure of pde9 in complex with ibmx |