|
95
|
316
|
1tszA |
Thymidylate synthase r179k mutant |
|
83
|
263
|
1tsnA |
Thymidylate synthase ternary complex with fdump and methylenetetrahydrofolate |
|
79
|
263
|
1tlsA |
Thymidylate synthase ternary complex with fdump and methylenetetrahydrofolate |
|
89
|
264
|
1trgA |
E. coli thymidylate synthase in symmetric complex with cb3717 and 2'-deoxyuridine 5'-monophosphate (dump) |
|
72
|
286
|
1tisA |
Crystal structure of thymidylate synthase from t4 phage |
|
97
|
316
|
1tvvA |
Contributions of orientation and hydrogen bonding to catalysis in asn-229 mutants of thymidylate synthase |
|
102
|
316
|
1tswA |
Thymidylate synthase r179a mutant |
|
100
|
316
|
1thyA |
Refined structures of substrate-bound and phosphate-bound thymidylate synthase from lactobacillus casei |
|
91
|
316
|
1tvwA |
Contributions of orientation and hydrogen bonding to catalysis in asn-229 mutants of thymidylate synthase |
|
103
|
316
|
1tsyA |
Thymidylate synthase r179k mutant |
|
92
|
316
|
1tvuA |
Contributions of orientation and hydrogen bonding to catalysis in asn-229 mutants of thymidylate synthase |
|
99
|
316
|
1tsvA |
Thymidylate synthase r179a mutant |
|
81
|
264
|
1tsdA |
Thymidylate synthase complex with 2'-deoxyuridine 5'-monophosphate (dump) and folate analog 1843u89 |
|
84
|
264
|
1tduA |
E. coli thymidylate synthase in complex with cb3717 and 2'-deoxyuridine (durd) |
|
99
|
316
|
1tsmA |
L. casei thymidylate synthase with species specific inhibitor |
|
98
|
316
|
1tslA |
L. casei thymidylate synthase with species specific inhibitor |
|
106
|
316
|
1tsxA |
Thymidylate synthase r179e mutant |
|
87
|
315
|
1tdcA |
Structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate |
|
74
|
264
|
1tlcA |
Thymidylate synthase complexed with dgmp and folate analog 1843u89 |
|
79
|
315
|
1tdbA |
Structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate |
|
80
|
264
|
1tjsA |
E. coli thymidylate synthase |
|
89
|
263
|
1tysA |
Water-mediated substrate(slash)product discrimination: the product complex of thymidylate synthase at 1.83 angstroms |
|
82
|
264
|
1synA |
E. coli thymidylate synthase in complex with bw1843u89 and 2'-deoxyuridine 5'-monophosphate (dump) |
|
94
|
315
|
1tdaA |
Structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate |
|
163
|
519
|
1sejA |
Crystal structure of dihydrofolate reductase-thymidylate synthase from cryptosporidium hominis bound to 1843u89/nadph/dump |
|
92
|
280
|
1rtsA |
Thymidylate synthase from rat in ternary complex with dump and tomudex |
|
166
|
519
|
1qzfA |
Crystal structure of dhfr-ts from cryptosporidium hominis |
|
74
|
263
|
1qqqA |
Crystal structure analysis of ser254 mutant of escherichia coli thymidylate synthase |
|
78
|
263
|
1nceA |
Crystal structure of a ternary complex of e. coli thymidylate synthase d169c with dump and the antifolate cb3717 |
|
97
|
316
|
1njeA |
Thymidylate synthase with 2'-deoxycytidine 5'-monophosphate (dcmp) |
|
96
|
316
|
1njdA |
Thymidylate synthase, mutation, n229d with 2'-deoxyuridine 5'-monophosphate (dump) |
|
100
|
316
|
1njcA |
Thymidylate synthase, mutation, n229d with 2'-deoxycytidine 5'-monophosphate (dcmp) |
|
101
|
316
|
1njaA |
Thymidylate synthase, mutation, n229c with 2'-deoxycytidine 5'-monophosphate (dcmp) |
|
92
|
316
|
1njbA |
Thymidylate synthase |
|
80
|
316
|
1lceA |
Lactobacillus casei thymidylate synthase ternary complex with dump and ch2thf |
|
83
|
316
|
1lcaA |
Lactobacillus casei thymidylate synthase ternary complex with dump and cb3717 |
|
83
|
263
|
1kziA |
Crystal structure of ects/dump/thf complex |
|
80
|
263
|
1kzjA |
Crystal structure of ects w80g/dump/cb3717 complex |
|
89
|
263
|
1kceA |
E. coli thymidylate synthase mutant e58q in complex with cb3717 and 2'-deoxyuridine 5'-monophosphate (dump) |
|
95
|
286
|
1ju6A |
Human thymidylate synthase complex with dump and ly231514, a pyrrolo(2,3-d)pyrimidine-based antifolate |
|
83
|
263
|
1jtuA |
E. coli thymidylate synthase in a complex with dump and ly338913, a polyglutamylated pyrrolo(2,3-d)pyrimidine-based antifolate |
|
83
|
286
|
1jujA |
Human thymidylate synthase bound to dump and ly231514, a pyrrolo(2,3-d)pyrimidine-based antifolate |
|
88
|
263
|
1jtqA |
E. coli ts complex with dump and the pyrrolo(2,3-d)pyrimidine-based antifolate ly341770 |
|
82
|
263
|
1jutA |
E. coli thymidylate synthase bound to dump and ly338529, a pyrrolo(2,3-d)pyrimidine-based antifolate |
|
103
|
326
|
1j3jC |
Double mutant (c59r+s108n) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with pyrimethamine, nadph, and dump |
|
78
|
285
|
1hw3A |
Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors |
|
75
|
285
|
1hw4A |
Structure of thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors |
|
93
|
288
|
1hvyA |
Human thymidylate synthase complexed with dump and raltitrexed, an antifolate drug, is in the closed conformation |
|
92
|
278
|
1i00A |
Crystal structure of human thymidylate synthase, ternary complex with dump and tomudex |
|
93
|
280
|
1hzwA |
Crystal structure of human thymidylate synthase |
