|
273
|
1013
|
5ubtA |
Crystal structure of pi3k delta in complex with a 7-(3-(piperazin-1-yl)phenyl)pyrrolo[2,1-f][1,2,4] triazin-4-amine deriviatine |
|
274
|
1015
|
5t8fA |
P110delta/p85alpha with taselisib (gdc-0032) |
|
293
|
1083
|
5sxbA |
Crystal structure of pi3kalpha in complex with fragment 23 |
|
284
|
1078
|
5sxjA |
Crystal structure of pi3kalpha in complex with fragment 29 |
|
309
|
1081
|
5sxdA |
Crystal structure of pi3kalpha in complex with fragment 22 |
|
303
|
1080
|
5sx9A |
Crystal structure of pi3kalpha in complex with fragment 14 |
|
286
|
1085
|
5sxaA |
Crystal structure of pi3kalpha in complex with fragment 10 |
|
251
|
919
|
5t2gA |
Mpi3kd in complex with 7i |
|
240
|
916
|
5t8iA |
Pi3kdelta in complex with the inhibitor gs-9901 |
|
309
|
1079
|
5swgA |
Crystal structure of pi3kalpha in complex with fragments 5 and 21 |
|
261
|
919
|
5t2iA |
Mpi3kd in complex with 7k |
|
301
|
1079
|
5sxkA |
Crystal structure of pi3kalpha in complex with fragment 18 |
|
302
|
1083
|
5sxiA |
Crystal structure of pi3kalpha in complex with fragment 13 |
|
291
|
1081
|
5sxeA |
Crystal structure of pi3kalpha in complex with fragments 19 and 28 |
|
286
|
1081
|
5swpA |
Crystal structure of pi3kalpha in complex with fragments 6 and 24 |
|
260
|
919
|
5t27A |
Mpi3kd in complex with 5d |
|
262
|
918
|
5t7fA |
Pi3kdelta in complex with the inhibitor gs-643624 |
|
304
|
1082
|
5swtA |
Crystal structure of pi3kalpha in complex with fragments 17 and 27 |
|
257
|
919
|
5t28A |
Mpi3kd in complex with 5k |
|
291
|
1081
|
5sx8A |
Crystal structure of pi3kalpha in complex with fragments 12 and 15 |
|
305
|
1079
|
5swrA |
Crystal structure of pi3kalpha in complex with fragments 20 and 26 |
|
299
|
1078
|
5sxfA |
Crystal structure of pi3kalpha in complex with fragment 9 |
|
282
|
1079
|
5sxcA |
Crystal structure of pi3kalpha in complex with fragment 8 |
|
259
|
919
|
5t2bA |
Mpi3kd in complex with 5e |
|
254
|
919
|
5t2dA |
Mpi3kd in complex with 7j |
|
253
|
942
|
5t23A |
Pi3kg in complex with 5d |
|
278
|
1080
|
5sw8A |
Crystal structure of pi3kalpha in complex with fragments 7 and 11 |
|
240
|
919
|
5t2mA |
Mpi3kd in complex with 7m |
|
264
|
947
|
5oq4A |
Pqr309 - a potent, brain-penetrant, orally bioavailable, pan-class i pi3k/mtor inhibitor as clinical candidate in oncology |
|
240
|
919
|
5o83A |
Discovery of cdz173 (leniolisib), representing a structurally novel class of pi3k delta-selective inhibitors |
|
278
|
946
|
5kaeA |
Crystal structure of human pi3k-gamma in complex with quinoline-containing inhibitor 5g |
|
233
|
920
|
5is5A |
Discovery and pharmacological characterization of novel quinazoline-based pi3k delta-selective inhibitors |
|
265
|
948
|
5g2nA |
X-ray structure of pi3kinase gamma in complex with copanlisib |
|
257
|
951
|
5g55A |
3-quinoline carboxamides inhibitors of pi3k |
|
298
|
945
|
5dxtA |
P110alpha with gdc-0326 |
|
278
|
943
|
4wwpA |
Crystal structure of human pi3k-gamma in complex with pyridinylquinoline inhibitor n-{(1s)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9h-purin-6-amine |
|
269
|
949
|
4xx5A |
Structure of pi3k gamma in complex with an inhibitor |
|
260
|
949
|
4xz4A |
Structure of pi3k gamma in complex with an inhibitor |
|
336
|
1060
|
4wafA |
Crystal structure of a novel tetrahydropyrazolo[1,5-a]pyrazine in an engineered pi3k alpha |
|
275
|
945
|
4wwnA |
Crystal structure of human pi3k-gamma in complex with (s)-n-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9h-purin-6-amine amg319 inhibitor |
|
263
|
944
|
4wwoA |
Crystal structure of human pi3k-gamma in complex with phenylquinoline inhibitor n-{(1s)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}-9h-purin-6-amine |
|
263
|
917
|
4xe0A |
Idelalisib bound to the p110 subunit of pi3k delta |
|
272
|
940
|
4tv3A |
Isolated p110a subunit of pi3ka provides a platform for structure-based drug design |
|
248
|
917
|
4v0iA |
Water network determines selectivity for a series of pyrimidone indoline amide pi3kbeta inhibitors over pi3k-delta |
|
265
|
940
|
4tuuA |
Isolated p110a subunit of pi3ka provides a platform for structure-based drug design |
|
317
|
1080
|
4ovuA |
Crystal structure of p110alpha in complex with nish2 of p85alpha |
|
264
|
949
|
4ps7A |
Structure of pi3k gamma in complex with n-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide |
|
272
|
949
|
4ps8A |
Structure of pi3k gamma in complex with n-[6-(5,6-dimethoxypyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide |
|
273
|
949
|
4ps3A |
Structure of pi3k gamma in complex with 1-[6-(5-methoxypyridin-3-yl)-1,3-benzothiazol-2-yl]-3-[2-(1-propyl-1h-imidazol-4-yl)ethyl]urea |
|
277
|
1081
|
4ovvA |
Crystal structure of pi3kalpha in complex with dic4-pip2 |
