79
|
324
|
8hy7A |
Egfr kinase domain mutant "tmlr" with compound 28f |
82
|
297
|
8j61A |
The crystal structure of trka kinase in complex with 4^6-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamide |
89
|
311
|
8j5wA |
The crystal structure of trka(f589l) kinase in complex with n-(3-cyclopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-4^6-methyl-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamide |
89
|
296
|
8j5xA |
The crystal structure of trka(g595r) kinase in complex with n-(3-cyclopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-4^6-methyl-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamide |
85
|
285
|
8pylAAA |
Human igf1r with inhibitor 53 |
86
|
287
|
8pymAAA |
Human igf1r with inhibitor 54 |
84
|
296
|
8j63A |
The crystal structure of trka kinase in complex with 4^6-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-11-oxo-5-oxa-10,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamide |
88
|
285
|
8pykAAA |
Human igf1r with inhibitor 47 |
83
|
324
|
8f1yA |
Egfr kinase in complex with poziotinib |
97
|
325
|
8f1zA |
Egfr kinase in complex with bayer #33 |
57
|
299
|
8h75A |
Fgfr2 in complex with yj001 |
82
|
307
|
8f1wA |
Egfr(t790m/v948r) kinase in complex with poziotinib |
93
|
322
|
8f1hA |
Egfr kinase in complex with tas6417 (cln-081) |
88
|
322
|
8g63A |
Ralimetinib (ly2228820) in complex with wild type egfr |
85
|
323
|
8h7xA |
Crystal structure of egfr t790m/c797s mutant in complex with brigatinib |
93
|
323
|
8f1xA |
Egfr kinase in complex with mobocertinib (tak-788) |
69
|
308
|
8emeA |
Egfr(t790m/v948r) in complex with znl-0056 |
85
|
297
|
8dwnA |
Crystal structure of bis-phosphorylated insulin receptor kinase domain |
85
|
296
|
8ov7A |
Crystal structure of d1228v c-met bound by compound 10 |
75
|
285
|
8owgA |
Crystal structure of d1228v c-met bound by compound 2 |
91
|
288
|
8ouuA |
Crystal structure of d1228v c-met bound by compound 29 |
96
|
294
|
8ouvA |
Crystal structure of d1228v c-met bound by compound 15 |
91
|
286
|
8ovzA |
Crystal structure of d1228v c-met bound by compound 16 |
29
|
183
|
8pe9A |
Complex between ddr1 ds-like domain and prth-101 fab |
25
|
213
|
7yswC |
Cryo-em structure of fgf23-fgfr4-aklotho-hs quaternary complex |
63
|
304
|
8stgA |
Discovery and clinical validation of rly-4008, the first highly selective fgfr2 inhibitor with activity across fgfr2 alterations and resistance mutations |
26
|
448
|
7zv9B |
Crystal structure of flt3 in complex with a monomeric flt3 ligand variant |
99
|
327
|
8cgcA |
Structure of csf1r in complex with a pyrollopyrimidine (compound 23) |
12
|
97
|
8s9pC |
1:1:1 agrin/lrp4/musk complex |
82
|
285
|
7zyqA |
Crystal structure of egfr-t790m/v948r in complex with reversible aminopyrimidine 13 |
93
|
322
|
7zynA |
Crystal structure of egfr-t790m/c797s in complex with wz4002 |
87
|
325
|
7zypA |
Crystal structure of egfr-t790m/c797s in complex with reversible aminopyrimidine 9 |
93
|
325
|
7zymA |
Crystal structure of egfr-t790m/c797s in complex with brigatinib |
128
|
897
|
7xlcA |
Conformation ii of apo-igf1r states |
28
|
213
|
7yshD |
Cryo-em structure of fgf23-fgfr1c-aklotho-hs quaternary complex |
28
|
211
|
7ysuC |
Cryo-em structure of fgf23-fgfr3c-aklotho-hs quaternary complex |
137
|
897
|
7xgdA |
Cryo-em structure of apo-igf1r map 1 |
69
|
475
|
8dfmA |
Ectodomain of full-length wild-type kit-scf dimers |
61
|
471
|
8dfqA |
Ectodomain of full-length kit(t417i,delta418-419)-scf dimers |
65
|
475
|
8dfpA |
Ectodomain of full-length kit(dupa502,y503)-scf dimers |
93
|
299
|
7xbiA |
The crystal structure of human trka kinase bound to the inhibitor |
97
|
593
|
8hgsA |
The egf-bound egfr ectodomain homodimer |
84
|
286
|
8bokA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 11 |
87
|
296
|
8bogA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 7 |
85
|
292
|
8bomA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 14 |
84
|
292
|
8bodA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 20 |
87
|
293
|
8bohA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 8 |
85
|
293
|
8boiA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 9 |
84
|
292
|
8bofA |
Crystal structure of ephrin a2 (epha2) receptor protein kinase with compound 12 |
101
|
321
|
7zw8A |
Identification of m4205 a highly selective inhibitor of ckit mutations for unresectable metastatic or recurrent gist |