|
311
|
1061
|
8am0A |
Crystal structure of human t1061e pi3kalpha in complex with its regulatory subunit and the inhibitor gdc-0077 (inavolisib) |
|
321
|
1043
|
8tsbA |
Human pi3k p85alpha/p110alpha bound to compound 2 |
|
321
|
1041
|
8ts7A |
Human pi3k p85alpha/p110alpha |
|
81
|
305
|
7rj6A |
Crystal structure of ap2 associated kinase 1 isoform 1 complexed with ligand (2r)-2-amino-n-[3-(difluorom ethoxy)-4-(1,3-oxazol-5-yl)phenyl]-4-methylpentanamide |
|
323
|
1045
|
8tsdA |
Human pi3k p85alpha/p110alpha bound to rly-2608 |
|
327
|
1049
|
8tsaA |
Human pi3k p85alpha/p110alpha h1047r bound to compound 2 |
|
332
|
1045
|
8ts9A |
Human pi3k p85alpha/p110alpha h1047r bound to compound 1 |
|
90
|
294
|
8g66C |
Structure with sj3149 |
|
79
|
273
|
8hmtA |
The complex of ack1 with the inhibitor 2-142 |
|
84
|
311
|
7sseA |
Crystal structure of the wdr domain of human dcaf1 in complex with cyca-117-70 |
|
113
|
346
|
7sqmA |
Discovery and preclinical pharmacology of ine963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cure in uncomplicated malaria |
|
57
|
137
|
7lb3A |
Crystal structure of the second bromodomain (bd2) of human taf1 bound to zs1-580 |
|
85
|
275
|
7kp6A |
Structure of ack1 kinase in complex with a selective inhibitor |
|
85
|
286
|
7fd0A |
Crystal structure of human ripk1 kinase domain in complex with a novel inhibitor |
|
78
|
285
|
7fczA |
Crystal structure of human ripk1 kinase domain in complex with a novel inhibitor |
|
82
|
304
|
7b8wA |
Structure of limk1 kinase domain with allosteric inhibitor th-470 |
|
114
|
873
|
8walA |
Structure of transcribing complex 3 (tc3), the initially transcribing complex with pol ii positioned 3nt downstream of tss. |
|
98
|
295
|
8x5zA |
The crystal structure of pak1 kinase domain from biortus. |
|
183
|
1189
|
8tzbA |
Structure of the c-terminal half of lrrk2 bound to gzd-824 (i2020t mutant) |
|
165
|
1189
|
8txzA |
Structure of c-terminal lrrk2 bound to mli-2 |
|
114
|
873
|
8wasA |
Structure of transcribing complex 9 (tc9), the initially transcribing complex with pol ii positioned 9nt downstream of tss. |
|
272
|
1896
|
8tzhA |
Structure of full-length lrrk2 bound to mli-2 (i2020t mutant) |
|
114
|
873
|
8waoA |
Structure of transcribing complex 5 (tc5), the initially transcribing complex with pol ii positioned 5nt downstream of tss. |
|
195
|
1190
|
8tzgA |
Structure of c-terminal lrrk2 bound to mli-2 (i2020t mutant) |
|
117
|
327
|
8qcdA |
Structure of protein kinase ck2 catalytic subunit (isoform ck2alpha'; csnk2a2 gene product) in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole |
|
301
|
1936
|
8tzfA |
Structure of full length lrrk2 bound to gzd-824 (i2020t mutant) |
|
192
|
1190
|
8tzcA |
Structure of c-terminal lrrk2 bound to mli-2 (g2019s mutant) |
|
112
|
327
|
8q9sA |
Structure of protein kinase ck2 catalytic subunit (isoform ck2alpha'; csnk2a2 gene product) in complex with the inhibitor sgc-ck2-1 |
|
218
|
1191
|
8tyqA |
Structure of the c-terminal half of lrrk2 bound to gzd-824 (g2019s mutant) |
|
114
|
873
|
8wakA |
Structure of transcribing complex 2 (tc2), the initially transcribing complex with pol ii positioned 2nt downstream of tss. |
|
182
|
899
|
8tzeA |
Structure of c-terminal half of lrrk2 bound to gzd-824 |
|
114
|
328
|
8qbuA |
Structure of protein kinase ck2 catalytic subunit (isoform ck2alpha'; csnk2a2 gene product) in complex with the inhibitor cx-4945 and the alpha-d-pocket ligand 3,4-dichloro phenethylamine (dpa) |
|
115
|
328
|
8q77A |
Structure of protein kinase ck2 catalytic subunit (isoform ck2alpha'; csnk2a2 gene product) in complex with the bisubstrate inhibitor arc-780 |
|
114
|
873
|
8wapA |
Structure of transcribing complex 6 (tc6), the initially transcribing complex with pol ii positioned 6nt downstream of tss. |
|
23
|
95
|
8gi4A |
Crystal structure of human limk2 pdz domain |
|
114
|
873
|
8waqA |
Structure of transcribing complex 7 (tc7), the initially transcribing complex with pol ii positioned 7nt downstream of tss. |
|
103
|
323
|
8qf1A |
Structure of the catalytic subunit of protein kinase ck2 (ck2alpha') in complex with the non-hydrolyzable gtp analogue gmppnp |
|
114
|
873
|
8wanA |
Structure of transcribing complex 4 (tc4), the initially transcribing complex with pol ii positioned 4nt downstream of tss. |
|
110
|
324
|
8qcgA |
Structure of the catalytic subunit of protein kinase ck2 (ck2alpha') in complex with the non-hydrolyzable atp analogue amppnp |
|
114
|
873
|
8warA |
Structure of transcribing complex 8 (tc8), the initially transcribing complex with pol ii positioned 8nt downstream of tss. |
|
91
|
295
|
8atbAAA |
Discovery of irak4 inhibitor 16 |
|
19
|
100
|
8p35A |
Mutant human titin immunoglobulin-like 21 domain - c3575s |
|
20
|
99
|
8ovuA |
Human titin immunoglobulin-like 21 domain |
|
95
|
291
|
7z4vA |
Structure of serine-threonine kinase stk25 in complex with compound |
|
79
|
289
|
7up5A |
Crystal structure of c-terminal domain of msk1 in complex with covalently bound pyrrolopyrimidine compound 23 (co-crystal) |
|
81
|
289
|
7up8A |
Crystal structure of c-terminal domain of msk1 in complex with covalently bound pyrrolopyrimidine compound 27 (co-crystal) |
|
83
|
289
|
7up4A |
Crystal structure of c-terminal domain of msk1 in complex with covalently bound pyrrolopyrimidine compound 20 (co-crystal) |
|
78
|
462
|
7v3vH |
Cryo-em structure of mcm double hexamer bound with ddk in state i |
|
140
|
482
|
7v3xC |
Crystal structure of cyanobacterial circadian clock protein kaic |
|
143
|
480
|
7v3xA |
Crystal structure of cyanobacterial circadian clock protein kaic |
