|
59
|
254
|
2flrH |
Novel 5-azaindole factor viia inhibitors |
|
58
|
254
|
2f9bH |
Discovery of novel heterocyclic factor viia inhibitors |
|
55
|
254
|
2flbH |
Discovery of a novel hydroxy pyrazole based factor ixa inhibitor |
|
28
|
142
|
2ec9L |
Crystal structure analysis of human factor viia , souluble tissue factor complexed with bcx-3607 |
|
57
|
254
|
2ec9H |
Crystal structure analysis of human factor viia , souluble tissue factor complexed with bcx-3607 |
|
30
|
139
|
2c4fL |
Crystal structure of factor vii.stf complexed with pd0297121 |
|
57
|
254
|
2c4fH |
Crystal structure of factor vii.stf complexed with pd0297121 |
|
11
|
53
|
2bz6L |
Orally available factor7a inhibitor |
|
55
|
254
|
2bz6H |
Orally available factor7a inhibitor |
|
57
|
254
|
2b7dH |
Factor viia inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in a baboon thrombosis model |
|
24
|
142
|
2b8oL |
Crystal structure of glu-gly-arg-chloromethyl ketone-factor viia/soluble tissue factor complex |
|
18
|
94
|
2b7dL |
Factor viia inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in a baboon thrombosis model |
|
50
|
254
|
2b8oH |
Crystal structure of glu-gly-arg-chloromethyl ketone-factor viia/soluble tissue factor complex |
|
52
|
254
|
2aeiH |
Crystal structure of a ternary complex of factor viia/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid |
|
57
|
254
|
2aerH |
Crystal structure of benzamidine-factor viia/soluble tissue factor complex. |
|
31
|
142
|
2aerL |
Crystal structure of benzamidine-factor viia/soluble tissue factor complex. |
|
28
|
142
|
2aeiL |
Crystal structure of a ternary complex of factor viia/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid |
|
54
|
254
|
2a2qH |
Complex of active-site inhibited human coagulation factor viia with human soluble tissue factor in the presence of ca2+, mg2+, na+, and zn2+ |
|
30
|
142
|
2a2qL |
Complex of active-site inhibited human coagulation factor viia with human soluble tissue factor in the presence of ca2+, mg2+, na+, and zn2+ |
|
55
|
254
|
1z6jH |
Crystal structure of a ternary complex of factor viia/tissue factor/pyrazinone inhibitor |
|
29
|
142
|
1z6jL |
Crystal structure of a ternary complex of factor viia/tissue factor/pyrazinone inhibitor |
|
10
|
53
|
1ygcL |
Short factor viia with a small molecule inhibitor |
|
58
|
254
|
1ygcH |
Short factor viia with a small molecule inhibitor |
|
30
|
142
|
1wqvL |
Human factor viia-tissue factor complexed with propylsulfonamide-d-thr-met-p-aminobenzamidine |
|
55
|
254
|
1wv7H |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-5-propoxy-trp-gln-p-aminobenzamidine |
|
31
|
142
|
1wv7L |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-5-propoxy-trp-gln-p-aminobenzamidine |
|
30
|
142
|
1wtgL |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-biphenylalanine-gln-p-aminobenzamidine |
|
56
|
254
|
1wunH |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-trp-gln-p-aminobenzamidine |
|
33
|
142
|
1wssL |
Human factor viia-tissue factor in complex with peptide-mimetic inhibitor that has two charged groups in p2 and p4 |
|
54
|
254
|
1wtgH |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-biphenylalanine-gln-p-aminobenzamidine |
|
58
|
254
|
1wqvH |
Human factor viia-tissue factor complexed with propylsulfonamide-d-thr-met-p-aminobenzamidine |
|
29
|
142
|
1wunL |
Human factor viia-tissue factor complexed with ethylsulfonamide-d-trp-gln-p-aminobenzamidine |
|
56
|
254
|
1wssH |
Human factor viia-tissue factor in complex with peptide-mimetic inhibitor that has two charged groups in p2 and p4 |
|
11
|
55
|
1w8bL |
Factor7 - 413 complex |
|
50
|
254
|
1w2kH |
Tf7a_4380 complex |
|
11
|
55
|
1w7xL |
Factor7 - 413 complex |
|
51
|
254
|
1w8bH |
Factor7 - 413 complex |
|
55
|
254
|
1w0yH |
Tf7a_3771 complex |
|
31
|
142
|
1w2kL |
Tf7a_4380 complex |
|
58
|
254
|
1w7xH |
Factor7 - 413 complex |
|
29
|
142
|
1w0yL |
Tf7a_3771 complex |
|
60
|
254
|
1qfkH |
Structure of human factor viia and its implications for the triggering of blood coagulation |
|
15
|
96
|
1qfkL |
Structure of human factor viia and its implications for the triggering of blood coagulation |
|
56
|
254
|
1o5dH |
Dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) |
|
16
|
96
|
1o5dL |
Dissecting and designing inhibitor selectivity determinants at the s1 site using an artificial ala190 protease (ala190 upa) |
|
12
|
61
|
1kliL |
Cofactor-and substrate-assisted activation of factor viia |
|
59
|
254
|
1kliH |
Cofactor-and substrate-assisted activation of factor viia |
|
58
|
254
|
1kljH |
Crystal structure of uninhibited factor viia |
|
16
|
56
|
1kljL |
Crystal structure of uninhibited factor viia |
|
54
|
250
|
1jbuH |
Coagulation factor vii zymogen (egf2/protease) in complex with inhibitory exosite peptide a-183 |
