|
154
|
413
|
6o2zA |
Crystal structure of idh1 r132h mutant in complex with compound 32 |
|
197
|
515
|
6d7kA |
Complex structure of methane monooxygenase hydroxylase in complex with inhibitory subunit |
|
66
|
256
|
6ninB |
Rhodobacter sphaeroides bc1 with stigmatellin a |
|
67
|
165
|
6d7kC |
Complex structure of methane monooxygenase hydroxylase in complex with inhibitory subunit |
|
20
|
64
|
6d7kD |
Complex structure of methane monooxygenase hydroxylase in complex with inhibitory subunit |
|
152
|
339
|
6d7kB |
Complex structure of methane monooxygenase hydroxylase in complex with inhibitory subunit |
|
109
|
368
|
6j39A |
Crystal structure of cmis2 with inhibitor |
|
156
|
428
|
6ninA |
Rhodobacter sphaeroides bc1 with stigmatellin a |
|
52
|
179
|
6ninC |
Rhodobacter sphaeroides bc1 with stigmatellin a |
|
86
|
318
|
6dq7A |
Linked kdm5a jmj domain bound to the potential hydrolysis product of inhibitor n45 i.e. 3-((6-(4-(2-cyano-3-methylbut-2-enoyl)-1,4-diazepan-1-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid |
|
86
|
318
|
6dqeA |
Linked kdm5a jmj domain bound to the inhibitor n67 i.e. 2-(5-phenyl-4-(phenyl(2-(piperidin-1-yl)ethoxy)methyl)-1h-pyrazol-1-yl)isonicotinic acid |
|
91
|
318
|
6dqcA |
Linked kdm5a jmj domain bound to the inhibitor n50 i.e. 2-(4-((2-(dimethylamino)ethyl)(ethyl)carbamoyl)-5-(4-methoxyphenyl)-1h-pyrazol-1-yl)isonicotinic acid |
|
90
|
317
|
6dqdA |
Linked kdm5a jmj domain bound to the inhibitor n53 i.e. 2-(5-([1,1'-biphenyl]-3-yl)-4-(1-(2-(piperidin-1-yl)ethoxy)ethyl)-1h-pyrazol-1-yl)isonicotinic acid |
|
86
|
318
|
6dqfA |
Linked kdm5a jmj domain bound to the inhibitor n68 i.e. 2-(1-(2-(piperidin-1-yl)ethyl)-1h-benzo[d]imidazol-2-yl)thieno[3,2-b]pyridine-7-carboxylic acid |
|
117
|
331
|
6baxA |
Lactate dehydrogenase in complex with inhibitor 6-(3-aminophenyl)-3-((2-chlorophenyl)thio)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2h-pyran-2-one |
|
132
|
421
|
5vv4A |
Structure of human neuronal nitric oxide synthase heme domain in complex with 4-(2-(((2-aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile |
|
110
|
331
|
6bb1A |
Lactate dehydrogenase in complex with inhibitor (r)-5-((2-chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1h)-one |
|
111
|
331
|
6bb3A |
Lactate dehydrogenase in complex with inhibitor 3-((2-chlorophenyl)thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2h-pyran-2-one |
|
113
|
331
|
6bazA |
Lactate dehydrogenase in complex with inhibitor (s)-5-((2-chlorophenyl)thio)-6'-((4-fluorophenyl)amino)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1h)-one |
|
101
|
291
|
5l01A |
Tryptophan 5-hydroxylase in complex with inhibitor (3~{s})-8-[2-azanyl-6-[(1~{r})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid |
|
1
|
10
|
5k4lF |
Crystal structure of kdm5a in complex with a naphthyridone inhibitor |
|
107
|
292
|
5j6dA |
Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors |
|
42
|
159
|
6e4eA |
Crystal structure of dihydrofolate reductase from staphylococcus aureus mw2 bound to nadp and p218 |
|
106
|
285
|
6dtpA |
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with em139 |
|
38
|
155
|
6cxmA |
Crystal structure of a dihydrofolate reductase from mycobacterium smegmatis in complex with nadp and p218 |
|
101
|
350
|
6cg1A |
Crystal structure of kdm4a with compound 14 |
|
104
|
348
|
6cg2A |
Crystal structure of kdm4a with compound 8 |
|
181
|
482
|
6c94A |
Structure of cytochrome p450 4b1 (cyp4b1) complexed with the inhibitor het0016 |
|
139
|
492
|
6btlA |
Crystal structure of trypanothione reductase from trypanosoma brucei in complex with inhibitor rd117 1-[2-(piperazin-1-yl)ethyl]-5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole |
|
138
|
492
|
6bu7A |
Crystal structure of trypanothione reductase from trypanosoma brucei in complex with inhibitor rd130 1-[2-(piperidin-4-yl)ethyl]-5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1h-indole |
|
21
|
70
|
6bmtB |
Crystal structure of a recombinant form of human myeloperoxidase bound to an inhibitor from staphylococcus delphini |
|
199
|
579
|
6bmtA |
Crystal structure of a recombinant form of human myeloperoxidase bound to an inhibitor from staphylococcus delphini |
|
85
|
318
|
6bh3A |
Linked kdm5a jmj domain bound to the inhibitor (s)-n-(1-(3-isopropyl-1h-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (compound n55) |
|
93
|
318
|
6bgyA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(1-methylpyrrolidin-2-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound 46) |
|
89
|
317
|
6bgxA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)((4,4-difluorocyclohexyl)methoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n42) |
|
84
|
318
|
6bh0A |
Linked kdm5a jmj domain bound to the inhibitor (r)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n51) |
|
121
|
394
|
6bdoA |
Structure of bacterial type ii nadh dehydrogenase from caldalkalibacillus thermarum complexed with a quinone inhibitor hqno at 2.8a resolution |
|
89
|
318
|
6bguA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine (compound n9) |
|
88
|
318
|
6bgvA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n40) |
|
86
|
318
|
6bh2A |
Linked kdm5a jmj domain bound to the inhibitor (r)-n-(1-(3-isopropyl-1h-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (compound n54) |
|
88
|
317
|
6bh5A |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(3-(piperidin-1-yl)propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n48) |
|
84
|
318
|
6bh4A |
Linked kdm5a jmj domain bound to the inhibitor 5-(1-(tert-butyl)-1h-pyrazol-4-yl)-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (compound n75/cpi-48) |
|
87
|
318
|
6bgwA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n41) |
|
86
|
318
|
6bh1A |
Linked kdm5a jmj domain bound to the inhibitor (s)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n52) |
|
134
|
418
|
6auvA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-(2-(5-(3-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine |
|
132
|
418
|
6auwA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-(2-(5-(4-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine |
|
135
|
421
|
6av4A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 4-methyl-6-(2-(5-(4-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine |
|
134
|
421
|
6av3A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 4-methyl-6-(2-(5-(3-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine |
|
134
|
421
|
6av5A |
Structure of human neuronal nitric oxide synthase r354a/g356d mutant heme domain in complex with 6-(2-(5-fluoro-3'-((methylamino)methyl)-[1,1'-biphenyl]-3-yl)ethyl)-4-methylpyridin-2-amine |
|
130
|
418
|
6auxA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-fluoro-3'-((methylamino)methyl)-[1,1'-biphenyl]-3-yl)ethyl)-4-methylpyridin-2-amine |
