|
89
|
276
|
5av0A |
Crystal structure of dapk1 in complex with 7,3',4'-trihydroxyisoflavone. |
|
76
|
262
|
4zs0A |
Human aurora a catalytic domain bound to sb-6-oh |
|
21
|
68
|
5e0yA |
Crystal structure of pasta domain 4 of mycobacterium tuberculosis protein kinase b |
|
88
|
307
|
5ar2A |
Rip2 kinase catalytic domain (1 - 310) |
|
6
|
23
|
5et1C |
Crystal structure of myo3b-arb1 in complex with espin1-ar |
|
18
|
43
|
5eofC |
Crystal structure of optn ntd and tbk1 ctd complex |
|
198
|
1435
|
5dfzB |
Structure of vps34 complex ii from s. cerevisiae. |
|
54
|
202
|
5e12A |
Crystal structure of pasta domains 2, 3 and 4 of mycobacterium tuberculosis protein kinase b |
|
77
|
302
|
5ar8A |
Rip2 kinase catalytic domain (1 - 310) complex with biphenylsulfonamide |
|
85
|
306
|
5ar4A |
Rip2 kinase catalytic domain (1 - 310) complex with sb-203580 |
|
79
|
273
|
5eolA |
Crystal structure of human pim-1 kinase in complex with a macrocyclic quinoxaline-pyrrolodihydropiperidinone inhibitor |
|
93
|
316
|
5eakA |
Optimization of microtubule affinity regulating kinase (mark) inhibitors with improved physical properties |
|
39
|
136
|
5e0zA |
Crystal structure of pasta domains 3 and 4 of mycobacterium tuberculosis protein kinase b |
|
86
|
305
|
5ar7A |
Rip2 kinase catalytic domain (1 - 310) complex with biaryl urea |
|
1
|
20
|
5et0B |
Crystal structure of myo3b-arb2 in complex with espin1-ar |
|
18
|
43
|
5eoaC |
Crystal structure of optn e50k mutant and tbk1 complex |
|
36
|
133
|
5e10A |
Crystal structure of pasta domains 1 and 2 of mycobacterium tuberculosis protein kinase b |
|
87
|
307
|
5ar5A |
Rip2 kinase catalytic domain (1 - 310) complex with benzimidazole |
|
86
|
264
|
5ew9A |
Crystal structure of aurora a kinase domain bound to mk-5108 |
|
16
|
46
|
5ep6B |
The crystal structure of nap1 in complex with tbk1 |
|
6
|
21
|
4zrkE |
Merlin-ferm and lats1 complex |
|
7
|
20
|
4zriC |
Crystal structure of merlin-ferm and lats2 |
|
77
|
267
|
5f4nA |
Multi-parameter lead optimization to give an oral chk1 inhibitor clinical candidate: (r)-5-((4-((morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (cct245737) |
|
87
|
305
|
5ar3A |
Rip2 kinase catalytic domain (1 - 310) complex with amp-pcp |
|
89
|
317
|
5es1A |
Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor |
|
82
|
264
|
5dt0A |
Aurora a kinase in complex with jnj-7706621 in space group p6122 |
|
80
|
264
|
5dr6A |
Aurora a kinase in complex with aa30 and jnj-7706621 in space group p6122 |
|
81
|
264
|
5drdA |
Aurora a kinase in complex with atp in space group p6122 |
|
84
|
263
|
5dpvA |
Aurora a kinase in complex with aa35 and jnj-7706621 in space group p6122 |
|
84
|
264
|
5dr2A |
Aurora a kinase in complex with aa30 and atp in space group p6122 |
|
83
|
264
|
5dt4A |
Aurora a kinase in complex with aa35 and atp in space group p6122 |
|
81
|
274
|
5dwrA |
Identification of n-(4-((1r,3s,5s)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (pim447), a potent and selective proviral insertion site of moloney murine leukemia (pim) 1,2 and 3 kinase inhibitor in clinical trials for hematological malignancies |
|
82
|
264
|
5dt3A |
Aurora a kinase in complex with atp in space group p6122 |
|
82
|
264
|
5dr9A |
Aurora a kinase in complex with aa29 and jnj-7706621 in space group p6122 |
|
84
|
273
|
5drbA |
Crystal structure of wnk1 in complex with wnk463 |
|
85
|
265
|
5dnrA |
Aurora a kinase in complex with atp in space group p41212 |
|
79
|
273
|
5diaA |
Pim1 in complex with cpd36 ((1s,3s)-n1-(6-(5-(pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridin-3-yl)pyridin-2-yl)cyclohexane-1,3-diamine) |
|
80
|
273
|
5dgzA |
Discovery of 3,5-substituted 6-azaindazoles as potent pan-pim inhibitors |
|
76
|
301
|
5dbxA |
Crystal structure of murine spak(t243d) in complex with amppnp |
|
78
|
265
|
5dlsA |
Identification of novel, in vivo active chk1 inhibitors utilizing structure guided drug design |
|
83
|
264
|
5dosA |
Aurora a kinase in complex with aa35 and atp in space group p6122 |
|
85
|
311
|
5d9lA |
Rsk2 n-terminal kinase in complex with bis-phenol pyrazole |
|
84
|
265
|
5dn3A |
Aurora a in complex with atp and aa35. |
|
87
|
281
|
5de2A |
Structural mechanism of nek7 activation by nek9-induced dimerisation |
|
19
|
253
|
4yzyA |
Crystal structures reveal transient perk luminal domain tetramerization in er stress signaling |
|
83
|
273
|
5dhjA |
Pim1 in complex with cpd4 (3-methyl-5-(pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridine) |
|
2
|
13
|
5dhfD |
Crystal structure of hrio2 nes peptide in complex with crm1-ran-ranbp1 |
|
76
|
289
|
5dh3A |
Crystal structure of mst2 in complex with xmu-mp-1 |
|
79
|
299
|
5d9hA |
Crystal structure of spak (stk39) dimer in the basal activity state |
|
88
|
300
|
5d7aA |
Crystal structure of the kinase domain of traf2 and nck-interacting protein kinase with ncb-0846 |
