|
102
|
349
|
5xsuA |
Novel orally efficacious inhibitors complexed with parp1 |
|
101
|
350
|
5xstA |
Novel orally efficacious inhibitors complexed with parp1 |
|
54
|
247
|
4oqbA |
Structure of human parp-1 bound to a dna double strand break in complex with (2z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide |
|
110
|
352
|
5ws1A |
Structure of human parp1 catalytic domain bound to a benzoimidazole inhibitor |
|
111
|
352
|
5wrqA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
|
112
|
352
|
5wtcA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
|
47
|
189
|
5v7tA |
Crystal structure of parp14 bound to n-{4-[4-(diphenylmethoxy)piperidin-1-yl]butyl}[1,2,4]triazolo[4,3-b]pyridazin-6-amine inhibitor |
|
43
|
188
|
5v7wA |
Crystal structure of human parp14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3h)-one inhibitor |
|
67
|
210
|
5owtA |
Crystal structure of tnks2 in complex with (5s)-5-methyl-5-[4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]imidazolidine-2,4-dione |
|
68
|
210
|
5owsA |
Crystal structure of tnks2 in complex with 2-[4-(4-methyl-2-oxoimidazolidin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nveH |
Crystal structure of tnks2 in complex with 2-(4-ethoxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nt4H |
Crystal structure of tnks2 in complex with 2-[4-(morpholin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
46
|
161
|
5nwcA |
Crystal structure of tnks2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nvhI |
Crystal structure of tnks2 in complex with 2-[4-(piperidin-1-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
160
|
5nwgA |
Crystal structure of tnks2 in complex with 7-chloro-2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nvcC |
Crystal structure of tnks2 in complex with 2-(3-hydroxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwbC |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwdH |
Crystal structure of tnks2 in complex with 2-[4-(diethylamino)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nvfA |
Crystal structure of tnks2 in complex with 2-[4-(pyridin-2-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
46
|
161
|
5nt4A |
Crystal structure of tnks2 in complex with 2-[4-(morpholin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
51
|
161
|
5nxeA |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one |
|
50
|
161
|
5nwbA |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nvcA |
Crystal structure of tnks2 in complex with 2-(3-hydroxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nxeH |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one |
|
1
|
47
|
5nwcH |
Crystal structure of tnks2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nwdA |
Crystal structure of tnks2 in complex with 2-[4-(diethylamino)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
162
|
5nveA |
Crystal structure of tnks2 in complex with 2-(4-ethoxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwgH |
Crystal structure of tnks2 in complex with 7-chloro-2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
69
|
210
|
5nutA |
Crystal structure of tnks2 in complex with 2-[4-(propan-2-yloxy)phenyl]-3,4-dihydroquinazolin-4-one |
|
70
|
189
|
5o2dA |
Parp14 macrodomain 2 with inhibitor |
|
1
|
47
|
5nvfH |
Crystal structure of tnks2 in complex with 2-[4-(pyridin-2-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
47
|
161
|
5nvhA |
Crystal structure of tnks2 in complex with 2-[4-(piperidin-1-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nsxC |
Crystal structure of tnks2 in complex with 2-(1h-indazol-5-yl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nspC |
Crystal structure of tnks2 in complex with od334 |
|
63
|
210
|
5nobA |
Crystal structure of human tankyrase 2 in complex with od336 |
|
1
|
47
|
5nt0C |
Crystal structure of tnks2 in complex with 2-(3-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
43
|
161
|
5nspA |
Crystal structure of tnks2 in complex with od334 |
|
49
|
190
|
5nqeA |
Human parp14 (artd8), catalytic fragment in complex with an n-aryl piperazine inhibitor |
|
65
|
210
|
5aehA |
Crystal structure of human tankyrase 2 in complex with od332 |
|
47
|
161
|
5nsxA |
Crystal structure of tnks2 in complex with 2-(1h-indazol-5-yl)-3,4-dihydroquinazolin-4-one |
|
1
|
46
|
5adsB |
Crystal structure of human tankyrase 2 in complex with od39 |
|
49
|
161
|
5nt0A |
Crystal structure of tnks2 in complex with 2-(3-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
46
|
5c5qC |
Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor |
|
47
|
161
|
5c5qA |
Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor |
|
1
|
46
|
5c5pC |
Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor |
|
1
|
48
|
5c5rC |
Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor |
|
48
|
161
|
5c5rA |
Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor |
|
147
|
462
|
5jhqA |
Arcs 1-3 of human tankyrase-1 bound to a peptide derived from irap |
|
111
|
352
|
5kpnA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
|
112
|
350
|
5kpqA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
