|
58
|
176
|
3v2bA |
Human poly(adp-ribose) polymerase 15 (artd7, bal3), macro domain 2 in complex with adenosine-5-diphosphoribose |
|
64
|
209
|
3uh2A |
Tankyrase-1 in complexed with pj34 |
|
69
|
210
|
3u9hA |
Complex structure of human tankyrase 2 with nicotinamide |
|
65
|
210
|
3u9yA |
Crystal structure of human tankyrase 2 catalytic domain in complex with olaparib |
|
108
|
320
|
3utmA |
Crystal structure of a mouse tankyrase-axin complex |
|
68
|
210
|
3ua9A |
Crystal structure of human tankyrase 2 in complex with a selective inhibitor |
|
68
|
212
|
3uh4A |
Tankyrase-1 complexed with nvp-xav939 |
|
62
|
211
|
3uddA |
Tankyrase-1 in complex with small molecule inhibitor |
|
51
|
164
|
3twqA |
Crystal structure of arc4 from human tankyrase 2 (apo form) |
|
50
|
155
|
3twvA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human numa1 (chimeric peptide) |
|
52
|
160
|
3twuA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human mcl1 |
|
51
|
158
|
3twxA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human fnbp1 (chimeric peptide) |
|
48
|
157
|
3twrA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human 3bp2 |
|
47
|
156
|
3twtA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human mcl1 (chimeric peptide) |
|
48
|
157
|
3twsA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human terf1 (chimeric peptide) |
|
51
|
157
|
3twwA |
Crystal structure of arc4 from human tankyrase 2 in complex with peptide from human lnpep (chimeric peptide) |
|
51
|
188
|
3smjA |
Human poly(adp-ribose) polymerase 14 (parp14/artd8) - catalytic domain in complex with a pyrimidine-like inhibitor |
|
48
|
187
|
3smiA |
Human poly(adp-ribose) polymerase 14 (parp14/artd8) - catalytic domain in complex with a quinazoline inhibitor |
|
52
|
189
|
3se2A |
Human poly(adp-ribose) polymerase 14 (parp14/artd8) - catalytic domain in complex with 6(5h)-phenanthridinone |
|
101
|
350
|
5xstA |
Novel orally efficacious inhibitors complexed with parp1 |
|
102
|
349
|
5xsuA |
Novel orally efficacious inhibitors complexed with parp1 |
|
54
|
247
|
4oqbA |
Structure of human parp-1 bound to a dna double strand break in complex with (2z)-2-{4-[2-(morpholin-4-yl)ethoxy]benzylidene}-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide |
|
110
|
352
|
5ws1A |
Structure of human parp1 catalytic domain bound to a benzoimidazole inhibitor |
|
111
|
352
|
5wrqA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
|
112
|
352
|
5wtcA |
Structure of human parp1 catalytic domain bound to a quinazoline-2,4(1h,3h)-dione inhibitor |
|
47
|
189
|
5v7tA |
Crystal structure of parp14 bound to n-{4-[4-(diphenylmethoxy)piperidin-1-yl]butyl}[1,2,4]triazolo[4,3-b]pyridazin-6-amine inhibitor |
|
43
|
188
|
5v7wA |
Crystal structure of human parp14 bound to 2-{[(1-methylpiperidin-4-yl)methyl]amino}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3h)-one inhibitor |
|
67
|
210
|
5owtA |
Crystal structure of tnks2 in complex with (5s)-5-methyl-5-[4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]imidazolidine-2,4-dione |
|
68
|
210
|
5owsA |
Crystal structure of tnks2 in complex with 2-[4-(4-methyl-2-oxoimidazolidin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
50
|
161
|
5nwbA |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nvcA |
Crystal structure of tnks2 in complex with 2-(3-hydroxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nxeH |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one |
|
1
|
47
|
5nwcH |
Crystal structure of tnks2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nveH |
Crystal structure of tnks2 in complex with 2-(4-ethoxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nt4H |
Crystal structure of tnks2 in complex with 2-[4-(morpholin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
46
|
161
|
5nwcA |
Crystal structure of tnks2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nvhI |
Crystal structure of tnks2 in complex with 2-[4-(piperidin-1-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
160
|
5nwgA |
Crystal structure of tnks2 in complex with 7-chloro-2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nvcC |
Crystal structure of tnks2 in complex with 2-(3-hydroxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwbC |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwdH |
Crystal structure of tnks2 in complex with 2-[4-(diethylamino)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nvfA |
Crystal structure of tnks2 in complex with 2-[4-(pyridin-2-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
46
|
161
|
5nt4A |
Crystal structure of tnks2 in complex with 2-[4-(morpholin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
51
|
161
|
5nxeA |
Crystal structure of tnks2 in complex with 2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-1,2,3,4-tetrahydroquinazolin-4-one |
|
1
|
47
|
5nvfH |
Crystal structure of tnks2 in complex with 2-[4-(pyridin-2-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
47
|
161
|
5nvhA |
Crystal structure of tnks2 in complex with 2-[4-(piperidin-1-yl)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
161
|
5nwdA |
Crystal structure of tnks2 in complex with 2-[4-(diethylamino)phenyl]-3,4-dihydroquinazolin-4-one |
|
49
|
162
|
5nveA |
Crystal structure of tnks2 in complex with 2-(4-ethoxyphenyl)-3,4-dihydroquinazolin-4-one |
|
1
|
47
|
5nwgH |
Crystal structure of tnks2 in complex with 7-chloro-2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one |
|
69
|
210
|
5nutA |
Crystal structure of tnks2 in complex with 2-[4-(propan-2-yloxy)phenyl]-3,4-dihydroquinazolin-4-one |
