|
278
|
946
|
5kaeA |
Crystal structure of human pi3k-gamma in complex with quinoline-containing inhibitor 5g |
|
233
|
920
|
5is5A |
Discovery and pharmacological characterization of novel quinazoline-based pi3k delta-selective inhibitors |
|
265
|
948
|
5g2nA |
X-ray structure of pi3kinase gamma in complex with copanlisib |
|
257
|
951
|
5g55A |
3-quinoline carboxamides inhibitors of pi3k |
|
298
|
945
|
5dxtA |
P110alpha with gdc-0326 |
|
278
|
943
|
4wwpA |
Crystal structure of human pi3k-gamma in complex with pyridinylquinoline inhibitor n-{(1s)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9h-purin-6-amine |
|
269
|
949
|
4xx5A |
Structure of pi3k gamma in complex with an inhibitor |
|
260
|
949
|
4xz4A |
Structure of pi3k gamma in complex with an inhibitor |
|
336
|
1060
|
4wafA |
Crystal structure of a novel tetrahydropyrazolo[1,5-a]pyrazine in an engineered pi3k alpha |
|
275
|
945
|
4wwnA |
Crystal structure of human pi3k-gamma in complex with (s)-n-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9h-purin-6-amine amg319 inhibitor |
|
263
|
944
|
4wwoA |
Crystal structure of human pi3k-gamma in complex with phenylquinoline inhibitor n-{(1s)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}-9h-purin-6-amine |
|
263
|
917
|
4xe0A |
Idelalisib bound to the p110 subunit of pi3k delta |
|
272
|
940
|
4tv3A |
Isolated p110a subunit of pi3ka provides a platform for structure-based drug design |
|
248
|
917
|
4v0iA |
Water network determines selectivity for a series of pyrimidone indoline amide pi3kbeta inhibitors over pi3k-delta |
|
265
|
940
|
4tuuA |
Isolated p110a subunit of pi3ka provides a platform for structure-based drug design |
|
317
|
1080
|
4ovuA |
Crystal structure of p110alpha in complex with nish2 of p85alpha |
|
264
|
949
|
4ps7A |
Structure of pi3k gamma in complex with n-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide |
|
272
|
949
|
4ps8A |
Structure of pi3k gamma in complex with n-[6-(5,6-dimethoxypyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide |
|
273
|
949
|
4ps3A |
Structure of pi3k gamma in complex with 1-[6-(5-methoxypyridin-3-yl)-1,3-benzothiazol-2-yl]-3-[2-(1-propyl-1h-imidazol-4-yl)ethyl]urea |
|
277
|
1081
|
4ovvA |
Crystal structure of pi3kalpha in complex with dic4-pip2 |
|
326
|
1052
|
4l23A |
Crystal structure of p110alpha complexed with nish2 of p85alpha and pi-103 |
|
319
|
1051
|
4l1bA |
Crystal structure of p110alpha complexed with nish2 of p85alpha |
|
246
|
949
|
4kz0A |
Structure of pi3k gamma with imidazopyridine inhibitors |
|
340
|
1060
|
4jpsA |
Co-crystal structures of the lipid kinase pi3k alpha with pan and isoform selective inhibitors |
|
240
|
949
|
4kzcA |
Structure of pi3k gamma with imidazopyridine inhibitors |
|
308
|
1046
|
4l2yA |
Crystal structure of p110alpha complexed with nish2 of p85alpha and compound 9d |
|
264
|
945
|
4j6iA |
Discovery of thiazolobenzoxepin pi3-kinase inhibitors that spare the pi3-kinase beta isoform |
|
273
|
949
|
4gb9A |
Potent and highly selective benzimidazole inhibitors of pi3k-delta |
|
284
|
948
|
4fulA |
Pi3 kinase gamma bound to a pyrmidine inhibitor |
|
277
|
948
|
4flhA |
Crystal structure of human pi3k-gamma in complex with amg511 |
|
233
|
946
|
4g11A |
X-ray structure of pi3k-gamma bound to a 4-(morpholin-4-yl)- (6-oxo-1,6-dihydropyrimidin-2-yl)amide inhibitor |
|
254
|
942
|
4fjzA |
Crystal structure of pi3k-gamma in complex with pyrrolo-pyridine inhibitor 63 |
|
270
|
945
|
4fjyA |
Crystal structure of pi3k-gamma in complex with quinoline-indoline inhibitor 24f |
|
262
|
948
|
4fhkA |
Crystal structure of pi3k-gamma in complex with imidazopyridazine 19e |
|
276
|
948
|
4fhjA |
Crystal structure of pi3k-gamma in complex with imidazopyridine 2 |
|
262
|
946
|
3qk0A |
Crystal structure of pi3k-gamma in complex with benzothiazole 82 |
|
263
|
945
|
3qaqA |
Crystal structure of pi3k-gamma in complex with triazine-benzimidazole 1 |
|
279
|
946
|
3qarA |
Crystal structure of pi3k-gamma in complex with triazine-benzimidazole 32 |
|
261
|
943
|
3qjzA |
Crystal structure of pi3k-gamma in complex with benzothiazole 1 |
|
263
|
950
|
3przA |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
|
265
|
950
|
3ps6A |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
|
267
|
950
|
3preA |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
|
267
|
949
|
3p2bA |
Crystal structure of pi3k gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol |
|
271
|
950
|
3oawA |
4-methylpteridineones as orally active and selective pi3k/mtor dual inhibitors |
|
266
|
946
|
3nzsA |
Structure-based optimization of pyrazolo -pyrimidine and -pyridine inhibitors of pi3-kinase |
|
268
|
947
|
3nzuA |
Structure-based optimization of pyrazolo -pyrimidine and -pyridine inhibitors of pi3-kinase |
|
260
|
950
|
3ml8A |
Discovery of the highly potent pi3k/mtor dual inhibitor pf-04691502 through structure based drug design |
|
278
|
950
|
3ml9A |
Discovery of the highly potent pi3k/mtor dual inhibitor pf-04691502 through structure based drug design |
|
239
|
947
|
3mjwA |
Pi3 kinase gamma with a benzofuranone inhibitor |
|
263
|
948
|
3lj3A |
Pi3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor |
