326
|
1052
|
4l23A |
Crystal structure of p110alpha complexed with nish2 of p85alpha and pi-103 |
319
|
1051
|
4l1bA |
Crystal structure of p110alpha complexed with nish2 of p85alpha |
308
|
1046
|
4l2yA |
Crystal structure of p110alpha complexed with nish2 of p85alpha and compound 9d |
246
|
949
|
4kz0A |
Structure of pi3k gamma with imidazopyridine inhibitors |
340
|
1060
|
4jpsA |
Co-crystal structures of the lipid kinase pi3k alpha with pan and isoform selective inhibitors |
240
|
949
|
4kzcA |
Structure of pi3k gamma with imidazopyridine inhibitors |
264
|
945
|
4j6iA |
Discovery of thiazolobenzoxepin pi3-kinase inhibitors that spare the pi3-kinase beta isoform |
273
|
949
|
4gb9A |
Potent and highly selective benzimidazole inhibitors of pi3k-delta |
284
|
948
|
4fulA |
Pi3 kinase gamma bound to a pyrmidine inhibitor |
277
|
948
|
4flhA |
Crystal structure of human pi3k-gamma in complex with amg511 |
233
|
946
|
4g11A |
X-ray structure of pi3k-gamma bound to a 4-(morpholin-4-yl)- (6-oxo-1,6-dihydropyrimidin-2-yl)amide inhibitor |
276
|
948
|
4fhjA |
Crystal structure of pi3k-gamma in complex with imidazopyridine 2 |
254
|
942
|
4fjzA |
Crystal structure of pi3k-gamma in complex with pyrrolo-pyridine inhibitor 63 |
270
|
945
|
4fjyA |
Crystal structure of pi3k-gamma in complex with quinoline-indoline inhibitor 24f |
262
|
948
|
4fhkA |
Crystal structure of pi3k-gamma in complex with imidazopyridazine 19e |
262
|
946
|
3qk0A |
Crystal structure of pi3k-gamma in complex with benzothiazole 82 |
263
|
945
|
3qaqA |
Crystal structure of pi3k-gamma in complex with triazine-benzimidazole 1 |
279
|
946
|
3qarA |
Crystal structure of pi3k-gamma in complex with triazine-benzimidazole 32 |
261
|
943
|
3qjzA |
Crystal structure of pi3k-gamma in complex with benzothiazole 1 |
265
|
950
|
3ps6A |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
263
|
950
|
3przA |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
267
|
950
|
3preA |
Quinazolines with intra-molecular hydrogen bonding scaffold (imhbs) as pi3k/mtor dual inhibitors. |
267
|
949
|
3p2bA |
Crystal structure of pi3k gamma with 3-(2-morpholino-6-(pyridin-3-ylamino)pyrimidin-4-yl)phenol |
271
|
950
|
3oawA |
4-methylpteridineones as orally active and selective pi3k/mtor dual inhibitors |
266
|
946
|
3nzsA |
Structure-based optimization of pyrazolo -pyrimidine and -pyridine inhibitors of pi3-kinase |
268
|
947
|
3nzuA |
Structure-based optimization of pyrazolo -pyrimidine and -pyridine inhibitors of pi3-kinase |
260
|
950
|
3ml8A |
Discovery of the highly potent pi3k/mtor dual inhibitor pf-04691502 through structure based drug design |
278
|
950
|
3ml9A |
Discovery of the highly potent pi3k/mtor dual inhibitor pf-04691502 through structure based drug design |
239
|
947
|
3mjwA |
Pi3 kinase gamma with a benzofuranone inhibitor |
263
|
948
|
3lj3A |
Pi3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor |
253
|
949
|
3l13A |
Crystal structures of pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors |
261
|
949
|
3l17A |
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors for the treatment of cancer |
260
|
949
|
3l16A |
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors for the treatment of cancer |
272
|
947
|
3l08A |
Structure of pi3k gamma with a potent inhibitor: gsk2126458 |
271
|
952
|
3l54A |
Structure of pi3k gamma with inhibitor |
237
|
950
|
3ibeA |
Crystal structure of a pyrazolopyrimidine inhibitor bound to pi3 kinase gamma |
306
|
1084
|
3hhmA |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha and the drug wortmannin |
281
|
1089
|
3hizA |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha |
265
|
949
|
3eneA |
Complex of pi3k gamma with an inhibitor |
254
|
952
|
3dpdA |
Achieving multi-isoform pi3k inhibition in a series of substituted 3,4-dihydro-2h-benzo[1,4]oxazines |
259
|
949
|
3dbsA |
Structure of pi3k gamma in complex with gdc0941 |
268
|
945
|
3cstA |
Crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor e5e2 |
271
|
945
|
3csfA |
Crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor dw2 |
264
|
950
|
3apdA |
Crystal structure of human pi3k-gamma in complex with ch5108134 |
241
|
949
|
3apfA |
Crystal structure of human pi3k-gamma in complex with ch5039699 |
267
|
950
|
3apcA |
Crystal structure of human pi3k-gamma in complex with ch5132799 |
251
|
1045
|
2y3aA |
Crystal structure of p110beta in complex with icsh2 of p85beta and the drug gdc-0941 |
275
|
919
|
2x38A |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with ic87114. |
276
|
919
|
2wxpA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with gdc-0941. |
268
|
919
|
2wxqA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with as15. |