177
|
622
|
8ffjX |
Structure of zanidatamab bound to her2 |
63
|
568
|
8hgpA |
The ereg-bound egfr/her2 ectodomain complex |
98
|
452
|
7tyjA |
Cryo-em structure of insulin receptor-related receptor (irr) in apo-state captured at ph 7. the 3d refinement was focused on one of two halves with c1 symmetry applied |
146
|
884
|
7tykA |
Cryo-em structure of insulin receptor-related receptor (irr) in apo-state captured at ph 7. the 3d refinement was applied with c2 symmetry |
80
|
568
|
8hgoA |
The egf-bound egfr/her2 ectodomain complex |
88
|
576
|
8hgoB |
The egf-bound egfr/her2 ectodomain complex |
134
|
884
|
7tymA |
Cryo-em structure of insulin receptor-related receptor (irr) in active-state captured at ph 9. the 3d refinement was applied with c2 symmetry |
84
|
576
|
8hgpB |
The ereg-bound egfr/her2 ectodomain complex |
116
|
518
|
7qvkAAA |
Nm-02 in complex with her2-ecd |
39
|
368
|
7qdpE |
Crystal structure of flt3 t343i in complex with the canonical ligand fl |
91
|
321
|
7t4iA |
Crystal structure of wild type egfr in complex with tak-788 |
85
|
287
|
7t4jA |
Crystal structure of egfr_d770_n771insnpg/v948r in complex with tak-788 |
79
|
298
|
7xafA |
The crystal structure of trka kinase in complex with 4^6,14-dimethyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo- tetradecaphan-2-yne-45-carboxamide |
82
|
285
|
8gvjA |
Crystal structure of cmet kinase domain bound by d6808 |
85
|
295
|
7xhyA |
Crystal structure of mertk kinase domain with bms794833 |
88
|
290
|
8bioA |
Crystal structure of human ephrin type-a receptor 2 (epha2) kinase domain in complex with mral5 |
84
|
283
|
7y4tA |
Crystal structure of cmet kinase domain bound by compound 9i |
87
|
283
|
8binA |
Crystal structure of human ephrin type-a receptor 2 (epha2) kinase domain in complex with mr21 |
76
|
295
|
8e1xA |
Fgfr2 kinase domain in complex with a pyrazolo[1,5-a]pyrimidine analog (compound 29) |
82
|
284
|
7y4uA |
Crystal structure of cmet kinase domain bound by compound 9y |
94
|
325
|
7u99A |
Egfr kinase in complex with a macrocyclic inhibitor |
84
|
307
|
7u98A |
Egfr(t790m/v948r) in complex with a macrocyclic inhibitor |
89
|
325
|
7u9aA |
Egfr in complex with a macrocyclic inhibitor |
87
|
283
|
8bk0A |
Crystal structure of human ephrin type-a receptor 2 (epha2) kinase domain in complex with ldn-211904 |
88
|
323
|
7ukvA |
Wild type egfr in complex with lazertinib (yh25448) |
95
|
313
|
7ukwA |
Egfr(t790m/v948r) in complex with lazertinib (yh25448) |
87
|
300
|
7yc1A |
Crystal structure of fgfr4 kinase domain with 10d |
89
|
300
|
7ybxA |
Crystal structure of fgfr4(v550m) kinase domain with 10z |
87
|
300
|
7ybpA |
Crystal structure of fgfr4(v550l) kinase domain with 10z |
91
|
300
|
7yc3A |
Crystal structure of fgfr4 kinase domain with 10t |
85
|
300
|
7yboA |
Crystal structure of fgfr4 kinase domain with 10z |
134
|
798
|
7u23E |
Single-chain lcdv-1 viral insulin-like peptide bound to igf-1r ectodomain, leucine-zippered form |
164
|
908
|
8eyxA |
Cryo-em structure of 4 insulins bound full-length mouse ir mutant with physically decoupled alpha cts (c684s/c685s/c687s; denoted as ir-3cs) asymmetric conformation 1 |
144
|
910
|
8ez0A |
Cryo-em structure of 4 insulins bound full-length mouse ir mutant with physically decoupled alpha cts (c684s/c685s/c687s; denoted as ir-3cs) symmetric conformation |
172
|
904
|
8eyyA |
Cryo-em structure of 4 insulins bound full-length mouse ir mutant with physically decoupled alpha cts (c684s/c685s/c687s, denoted as ir-3cs) asymmetric conformation 2 |
138
|
901
|
8eyrA |
Cryo-em structure of two igf1 bound full-length mouse igf1r mutant (four glycine residues inserted in the alpha-ct; igf1r-p674g4): symmetric conformation |
136
|
907
|
8guyE |
Human insulin receptor bound with two insulin molecules |
100
|
907
|
7yq5E |
Human insulin receptor bound with a62 dna aptamer and insulin |
109
|
907
|
7yq6E |
Human insulin receptor bound with a62 dna aptamer |
14
|
108
|
7tydA |
Crystal structure of fgfr4 domain 3 in complex with a de novo-designed mini-binder in p21 space group |
121
|
907
|
7yq3E |
Human insulin receptor bound with a43 dna aptamer and insulin |
76
|
591
|
7yq4E |
Human insulin receptor bound with a62 dna aptamer and insulin - locally refined |
99
|
327
|
7si1A |
Crystal structure of apo egfr kinase domain |
93
|
321
|
8a2dA |
Egfr kinase domain (l858r/v948r) in complex with 2-[4-(difluoromethyl)-6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-7-methyl-indazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-n-thiazol-2-yl-acetamide |
84
|
289
|
8a2bA |
Egfr kinase domain (l858r/v948r) in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide |
100
|
320
|
8a2aA |
Egfr kinase domain in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide (form 2) |
89
|
285
|
8a27A |
Egfr kinase domain in complex with 2-(6,7-dihydro-5h-pyrrolo[1,2-c]imidazol-1-yl)-2-[6-[2-[4-[[4-(hydroxymethyl)-1-piperidyl]methyl]phenyl]ethynyl]-1-oxo-4-(trifluoromethyl)isoindolin-2-yl]-n-thiazol-2-yl-acetamide |
77
|
289
|
7u6dB |
Head region of insulin receptor ectodomain (a-isoform) bound to the non-insulin agonist im459 |
168
|
594
|
7u6eE |
Head region of insulin receptor ectodomain (a-isoform) bound to the non-insulin agonist im462 |
81
|
297
|
8arjA |
Anaplastic lymphoma kinase with a novel carboline inhibitor |