86
|
267
|
7kxlA |
Btk1 soaked with compound 5, y551 is sequestered |
85
|
290
|
6wtpA |
Human jak2 jh1 domain in complex with protac-intermediate linker handle 3 |
89
|
286
|
6wtqA |
Human jak2 jh1 domain in complex with protac-intermediate linker handle 4 |
92
|
293
|
6wtnA |
Human jak2 jh1 domain in complex with ruxolitinib |
93
|
292
|
6wtoA |
Human jak2 jh1 domain in complex with baricitinib |
96
|
298
|
6vnkA |
Jak2 jh1 in complex with pn4-073 |
95
|
298
|
6vnbA |
Jak2 jh1 in complex with bl2-084 |
93
|
297
|
6vncA |
Jak2 jh1 in complex with bl2-096 |
97
|
299
|
6vnjA |
Jak2 jh1 in complex with pn4-014 |
93
|
298
|
6vnfA |
Jak2 jh1 in complex with ma9-086 |
96
|
298
|
6vnhA |
Jak2 jh1 in complex with pn2-123 |
94
|
291
|
6vniA |
Jak2 jh1 in complex with pn3-115 |
96
|
298
|
6vn8A |
Jak2 jh1 in complex with baricitinib |
98
|
289
|
6vs3A |
Jak2 jh1 in complex with bl2-057 |
98
|
298
|
6vsnA |
Jak2 jh1 in complex with bl2-110 |
92
|
292
|
6vneA |
Jak2 jh1 in complex with fedratinib |
93
|
298
|
6vnmA |
Jak2 jh1 in complex with sy5-103 |
94
|
292
|
6vngA |
Jak2 jh1 in complex with pn2-118 |
90
|
298
|
6vnlA |
Jak2 jh1 in complex with sg3-179 |
57
|
273
|
6l8lA |
C-src in complex with ibrutinib |
94
|
290
|
7apfA |
Crystal structure of jak3 in complex with fm601 (compound 10a) |
90
|
290
|
6x8gA |
Crystal structure of tyk2 with compound 22 |
93
|
290
|
6x8fA |
Crystal structure of tyk2 with compound 11 |
91
|
291
|
7apgA |
Crystal structure of jak3 in complex with fm587 (compound 9a) |
31
|
167
|
6tvnA |
Crystal structure of 5-bromoindoline-2,3-dione covalently bound to the ph domain of bruton's tyrosine kinase |
97
|
305
|
6vglA |
Jak2 jh1 in complex with ruxolitinib |
84
|
267
|
6vxqA |
Bruton's tyrosine kinase in complex with compound 5 |
91
|
288
|
6x8eA |
Crystal structure of jak2 with compound 11 |
91
|
267
|
6w06A |
Bruton's tyrosine kinase in complex with compound 6 |
87
|
266
|
6w07A |
Bruton's tyrosine kinase in complex with compound 1 |
80
|
261
|
6w7oA |
Ternary complex structure - btk ciap compound 17 |
86
|
269
|
6xjkA |
Jak2 jh2 in complex with jak067 |
33
|
167
|
6tuhA |
The ph domain of bruton's tyrosine kinase mutant r28c |
34
|
168
|
6tt2A |
The ph domain of bruton's tyrosine kinase mutant r28c |
73
|
265
|
6w8iA |
Ternary complex structure - btk ciap compound 15 |
32
|
168
|
6tseA |
Crystal structure of 1-methylindoline-2,3-dione covalently bound to the ph domain of bruton's tyrosine kinase mutant r28c |
71
|
287
|
6xrgA |
Abl 1b isoform inactive2 state |
75
|
287
|
6xr6A |
Abl 1b isoform active state |
80
|
287
|
6xr7A |
Abl isoform 1b inactive1 state |
86
|
266
|
6i99A |
Bone marrow tyrosine kinase in chromosome x in complex with a newly designed covalent inhibitor js24 |
24
|
104
|
6htfA |
Crystal structure of human btk sh2 domain bound to rf10 repebody |
97
|
289
|
7c3nA |
Crystal structure of jak3 in complex with delgocitinib |
14
|
61
|
6xx5A |
Crystal structure of the c-src sh3 domain h122r-q128k mutant in complex with ni(ii) at ph 7.5 co-crystallized with methyl beta-cyclodextrin |
85
|
264
|
6xe4A |
Btk fluorocyclopropyl amide inhibitor, compound 25 |
83
|
268
|
6x3nA |
Co-structure of btk kinase domain with l-005085737 inhibitor |
93
|
266
|
6x3pA |
Co-structure of btk kinase domain with l-005298385 inhibitor |
88
|
265
|
6x3oA |
Co-structure of btk kinase domain with l-005191930 inhibitor |
79
|
275
|
6wiwA |
C-src bound to atp-competitive inhibitor i14 |
80
|
290
|
6tpfA |
Fragment-based discovery of pyrazolopyridones as jak1 inhibitors with excellent subtype selectivity |
92
|
289
|
6tpdA |
Fragment-based discovery of pyrazolopyridones as jak1 inhibitors with excellent subtype selectivity |