|
129
|
323
|
4zo5A |
Pde10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione |
|
129
|
322
|
4y8cA |
Crystal structure of phosphodiesterase 9 in complex with (s)-c33 |
|
124
|
322
|
4y87A |
Crystal structure of phosphodiesterase 9 in complex with (r)-c33 (6-{[(1r)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one) |
|
130
|
322
|
4y86A |
Crystal structure of pde9 in complex with racemic inhibitor c33 |
|
130
|
324
|
4xy2A |
Crystal structure of pde10a in complex with asp9436 |
|
138
|
318
|
4y2bA |
Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3h)-one bound to pde7a |
|
122
|
324
|
4wn1A |
Crystal structure of pde10a in complex with 1-methyl-5-(1-methyl-3-{[4-(quinolin-2-yl)phenoxy]methyl}-1h-pyrazol-4-yl)pyridin-2(1h)-one |
|
130
|
347
|
4wcuA |
Pde4 complexed with inhibitor |
|
166
|
492
|
4x0fA |
Crystal structure of crosslink stabilized long-form pde4b in complex with (r)-(-)-rolipram |
|
131
|
322
|
4w1oA |
Pde4d complexed with inhibitor |
|
171
|
492
|
4wziA |
Crystal structure of crosslink stabilized long-form pde4b |
|
123
|
305
|
4tppA |
2-(3-alkoxy-1-azetidinyl) quinolines as novel pde10a inhibitors |
|
115
|
303
|
4tpmA |
Crystal structure of 2-(3-alkoxy-1-azetidinyl) quinolines as pde10a inhibitors |
|
133
|
322
|
4qgeA |
Phosphodiesterase-9a in complex with inhibitor wyq-c36d |
|
127
|
307
|
4p0nA |
Crystal structure of pde10a with a novel imidazo[4,5-b]pyridine inhibitor |
|
122
|
305
|
4phwA |
Crystal structure of pde10a with 1h-benzimidazol-2-yl(4-((3-(tetrahydro-2h-pyran-4-yl)-2-pyridinyl)oxy)phenyl)methanone |
|
133
|
318
|
4p1rA |
Crystal structure of pde10a with imidazo[4,5-b]pyridines as potent and selective inhibitors |
|
137
|
318
|
4pm0A |
Pde7a catalytic domain in complex with 2-(cyclopentylamino)thieno[3,2-d]pyrimidin-4(3h)-one derivative |
|
138
|
330
|
4phlA |
Tbrpdeb1-inhibitor complex |
|
139
|
359
|
4nw7A |
Pde4 catalytic domain |
|
134
|
328
|
4ogbA |
Crystal structure of the catalytic domain of pde4d2 with compound 2 |
|
125
|
324
|
4oewA |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
|
123
|
327
|
4oexA |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
|
137
|
352
|
4npvA |
Crystal structure of human pde1b bound to inhibitor 7a (6,7,8-trimethoxy-n-(pentan-3-yl)quinazolin-4-amine) |
|
138
|
353
|
4npwA |
Crystal structure of human pde1b bound to inhibitor 19a (7,8-dimethoxy-n-[(2s)-1-(3-methyl-1h-pyrazol-5-yl)propan-2-yl]quinazolin-4-amine) |
|
142
|
357
|
4myqA |
Selective inhibition of the catalytic domain of human phosphodiesterase 4b with a-33 |
|
128
|
318
|
4muwA |
Crystal structure of pde10a with novel keto-benzimidazole inhibitor |
|
138
|
330
|
4mrzA |
Crystal structure of pde10a2 with fragment zt0429 (4-methyl-3-nitropyridin-2-amine) |
|
133
|
329
|
4lljA |
Crystal structure of pde10a2 with fragment zt214 |
|
136
|
330
|
4lm2A |
Crystal structure of pde10a2 with fragment zt462 |
|
125
|
307
|
4mvhA |
Crystal structure of pde10a with novel keto-benzimidazole inhibitor |
|
125
|
330
|
4mseA |
Crystal structure of pde10a2 with fragment zt1597 (2-({[(2s)-2-methyl-2,3-dihydro-1,3-benzothiazol-5-yl]oxy}methyl)quinoline) |
|
134
|
330
|
4lm0A |
Crystal structure of pde10a2 with fragment zt448 |
|
136
|
330
|
4llxA |
Crystal structure of pde10a2 with fragment zt434 |
|
126
|
328
|
4mshA |
Crystal structure of pde10a2 with fragment zt0143 ((2s)-4-chloro-2,3-dihydro-1,3-benzothiazol-2-amine) |
|
136
|
330
|
4mrwA |
Crystal structure of pde10a2 with fragment zt0120 (7-chloroquinolin-4-ol) |
|
138
|
330
|
4lm4A |
Crystal structure of pde10a2 with fragment zt902 |
|
134
|
332
|
4lm1A |
Crystal structure of pde10a2 with fragment zt450 |
|
134
|
330
|
4msnA |
Crystal structure of pde10a2 with fragment zt0451 (8-nitroquinoline) |
|
135
|
330
|
4ms0A |
Crystal structure of pde10a2 with fragment zt0443 (6-chloropyrimidine-2,4-diamine) |
|
136
|
330
|
4llkA |
Crystal structure of pde10a2 with fragment zt217 |
|
136
|
331
|
4lm3A |
Crystal structure of pde10a2 with fragment zt464 |
|
132
|
328
|
4mscA |
Crystal structure of pde10a2 with fragment zt1595 (2-[(quinolin-7-yloxy)methyl]quinoline) |
|
136
|
330
|
4msaA |
Crystal structure of pde10a2 with fragment zt0449 (5-nitro-1h-benzimidazole) |
|
118
|
326
|
4md6A |
Crystal structure of pde5 in complex with inhibitor 5r |
|
136
|
330
|
4lkqA |
Crystal structure of pde10a2 with fragment zt017 |
|
135
|
330
|
4llpA |
Crystal structure of pde10a2 with fragment zt401 |
|
141
|
324
|
4kp6A |
Crystal structure of human phosphodiesterase 4b (pde4b) in complex with a [1,3,5]triazine derivative |
|
134
|
333
|
4i15A |
Crystal structure of tbrpdeb1 |
|
120
|
324
|
4i9zA |
Crystal structure of the pde5a1 catalytic domain in complex with novel inhibitors |
