|
99
|
289
|
4ytfA |
Discovery of vx-509 (decernotinib): a potent and selective janus kinase (jak) 3 inhibitor for the treatment of autoimmune diseases |
|
89
|
291
|
4ymjA |
(r)-2-phenylpyrrolidine substitute imidazopyridazines: a new class of potent and selective pan-trk inhibitors |
|
93
|
271
|
4z3vA |
Fragment-based discovery of a small molecule reversible inhibitor of bruton's tyrosine kinase |
|
156
|
474
|
4ysjA |
Calcium-dependent protein kinase from eimeria tenella in complex with adp |
|
67
|
262
|
4yurA |
Crystal structure of plk4 kinase domain bound to centrinone |
|
159
|
473
|
4yuqA |
Cdpk1 from eimeria tenella in complex with inhibitor uw1354 |
|
116
|
349
|
4yu2A |
Crystal structure of dyrk1a with harmine-derivatized annh-75 inhibitor |
|
93
|
294
|
4yo4A |
Crystal structure of dapk1 catalytic domain in complex with the hinge binding fragment phthalazine |
|
98
|
328
|
4umrA |
Structure of melk in complex with inhibitors |
|
97
|
333
|
4umpA |
Structure of melk in complex with inhibitors |
|
107
|
331
|
4umuA |
Structure of melk in complex with inhibitors |
|
70
|
318
|
4un0C |
Crystal structure of the human cdk12-cyclink complex |
|
88
|
300
|
4tl0A |
Crystal structure of death-associated protein kinase 1 with a crucial phosphomimicking mutation |
|
96
|
265
|
4rx5A |
Bruton's tyrosine kinase (btk) with pyridazinone compound 23 |
|
82
|
298
|
4ez3A |
Cdk2 in complex with nsc 134199 |
|
97
|
290
|
4qmqA |
Mst3 in complex with cp-673451 |
|
75
|
276
|
4f1oA |
Crystal structure of the l1180t mutant roco4 kinase domain from d. discoideum bound to appcp |
|
117
|
348
|
4f9wA |
Human p38alpha mapk in complex with a novel and selective small molecule inhibitor |
|
88
|
299
|
4f64A |
Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with compound 6 |
|
90
|
297
|
4qqtA |
Crystal structure of fgf receptor (fgfr) 4 tyrosine kinase domain |
|
71
|
274
|
4pp7A |
Highly potent and selective 3-n-methylquinazoline-4(3h)-one based inhibitors of b-rafv600e kinase |
|
82
|
287
|
4hviA |
Jak3 kinase domain in complex with 2-cyclopropyl-5h-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((r)-1-methyl-2-oxo-2-piperidin-1-yl-ethyl)-amide |
|
91
|
290
|
4f08A |
Discovery and optimization of c-2 methyl imidazo-pyrrolopyridines as potent and orally bioavailable jak1 inhibitors with selectivity over jak2 |
|
93
|
290
|
4f0iA |
Crystal structure of apo trka |
|
80
|
276
|
4f0fA |
Crystal structure of the roco4 kinase domain bound to appcp from d. discoideum |
|
99
|
360
|
4f6sA |
Crystal structure of human cdk8/cycc in complex with compound 7 (1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea) |
|
88
|
299
|
4f63A |
Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with compound 1 |
|
93
|
308
|
4euuA |
Structure of bx-795 complexed with human tbk1 kinase domain phosphorylated on ser172 |
|
84
|
273
|
4f4pA |
Syk in complex with ligand lasw836 |
|
92
|
333
|
4q9zA |
Human protein kinase c theta in complex with compound35 ((1r)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1h)-one) |
|
108
|
386
|
4eutA |
Structure of bx-795 complexed with unphosphorylated human tbk1 kinase-uld domain |
|
95
|
360
|
4f70A |
Crystal structure of human cdk8/cycc in complex with compound 4 (1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[2-(morpholin-4-yl)ethyl]urea) |
|
87
|
302
|
4f65A |
Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with compound 8 |
|
91
|
291
|
4pmpA |
The structure of trka kinase bound to the inhibitor 1-cyclopropyl-1-[3-(1,3-thiazol-2-yl)benzyl]-3-[4-(trifluoromethoxy)phenyl]urea |
|
100
|
350
|
4eyjA |
Mapk13 complex with inhibitor |
|
104
|
361
|
4f6uA |
Crystal structure of human cdk8/cycc in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea) |
|
96
|
354
|
4f99A |
Human cdc7 kinase in complex with dbf4 and nucleotide |
|
103
|
350
|
4eymA |
Mapk13 complex with inhibitor |
|
81
|
277
|
4f0gA |
Crystal structure of the roco4 kinase domain from d. discoideum |
|
100
|
356
|
4f9aA |
Human cdc7 kinase in complex with dbf4 and nucleotide |
|
78
|
275
|
4ewhA |
Co-crystal structure of ack1 with inhibitor |
|
102
|
354
|
4f9cA |
Human cdc7 kinase in complex with dbf4 and xl413 |
|
91
|
361
|
4f7lA |
Crystal structure of human cdk8/cycc in complex with compound 2 (tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate) |
|
77
|
278
|
4f1mA |
Crystal structure of the g1179s roco4 kinase domain bound to appcp from d. discoideum. |
|
87
|
284
|
4qmnA |
Mst3 in complex with bosutinib |
|
94
|
303
|
4hw7A |
Crystal structure of fms kinase domain with a small molecular inhibitor, plx647-ome |
|
117
|
350
|
4fa2A |
Human p38 alpha mitogen-activated kinase in complex with sb239063 |
|
109
|
350
|
4erkA |
The complex structure of the map kinase erk2/olomoucine |
|
103
|
359
|
4f7sA |
Crystal structure of human cdk8/cycc in the dmg-in conformation |
|
65
|
291
|
4ez5A |
Cdk6 (monomeric) in complex with inhibitor |
