|
52
|
186
|
3s3vA |
Human dihydrofolate reductase q35k/n64f double mutant binary complex with trimethoprim |
|
58
|
218
|
3rg9A |
Trypanosoma brucei dihydrofolate reductase (tbdhfr) in complex with wr99210 |
|
41
|
159
|
5w3qA |
L28f e.coli dhfr in complex with nadph |
|
43
|
160
|
5uioA |
Structure of dhfr with bound dap, p-abg and nadp |
|
44
|
159
|
5ujxA |
Crystal structure of dhfr in 20% isopropanol |
|
42
|
159
|
5uiiA |
Structure of dhfr with bound buformin and nadp |
|
41
|
161
|
5ujfA |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound p218 inhibitor |
|
43
|
159
|
5uipA |
Structure of dhfr with bound dap, p-abg and nadp |
|
42
|
159
|
5uihA |
Structure of dhfr with bound phenformin and nadp |
|
42
|
166
|
5u27A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p65 inhibitor |
|
41
|
166
|
5u26A |
Crystal structure of mycobacterium tuberculosis dihydrofolate reductase bound to nadp and p218 inhibitor |
|
156
|
563
|
5t0lA |
Crystal structure of toxoplasma gondii ts-dhfr complexed with nadph, dump, pddf and 5-(4-(3,4-dichlorophenyl)piperazin-1-yl)pyrimidine-2,4-diamine (trc-15) |
|
52
|
186
|
5ht4A |
6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl) |
|
37
|
161
|
5hi6A |
The high resolution structure of dihydrofolate reductase from yersinia pestis complex with methotrexate as closed form |
|
40
|
157
|
5hf0X |
Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106) |
|
42
|
157
|
5hf2X |
Staphylococcus aureus dihydrofolate reductase complexed with cyclized alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1175) |
|
36
|
161
|
5fdaA |
The high resolution structure of apo form dihydrofolate reductase from yersinia pestis at 1.55 a |
|
45
|
159
|
5eajA |
Crystal structure of dhfr in 0% isopropanol |
|
45
|
159
|
5e8qA |
Crystal structure of dhfr in 20% isopropanol |
|
40
|
159
|
5dfrA |
Crystal structure of unliganded escherichia coli dihydrofolate reductase. ligand-induced conformational changes and cooperativity in binding |
|
40
|
157
|
4xe6X |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1061) |
|
40
|
157
|
4xecX |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1061) |
|
43
|
159
|
4x5iA |
Ecdhfr complexed with folate and nadp+ at 660 mpa |
|
44
|
159
|
4x5fA |
Ecdhfr complexed with folate and nadp+ at 0.1 mpa |
|
38
|
159
|
4x5jA |
Ecdhfr complexed with folate and nadp+ at 750 mpa |
|
42
|
159
|
4x5gA |
Ecdhfr complexed with folate and nadp+ at 270 mpa |
|
44
|
159
|
4x5hA |
Ecdhfr complexed with folate and nadp+ at 500 mpa |
|
41
|
157
|
4tu5X |
Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1062) |
|
56
|
206
|
4qjzD |
Pneumocystis carinii dihydrofolate reductase ternary complex with nadph and the inhibitor 24, (n~6~-methyl-n~6~-(naphthalen-1-yl)pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
50
|
186
|
4qjcA |
Human dihydrofolate reductase ternary complex with nadph and inhibitor 26 (n~6~-methyl-n~6~-(3,4,5-trifluorophenyl)pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
41
|
167
|
4qi9A |
Crystal structure of dihydrofolate reductase from yersinia pestis complexed with methotrexate |
|
47
|
159
|
4rgcA |
277k crystal structure of escherichia coli dihydrofolate reductase |
|
45
|
159
|
4qlfA |
Crystal structure of i14g dhfr mutant complexed with folate and nadp+ |
|
43
|
159
|
4qlgA |
Crystal structure of i14v dhfr mutant complexed with folate and nadp+ |
|
54
|
186
|
4qhvA |
Crystal structure of human dihydrofolate reductase as complex with pyridopyrimidine 22 (n~6~-methyl-n~6~-[4-(propan-2-yl)phenyl]pyrido[2,3-d]pyrimidine-2,4,6-triamine) |
|
45
|
159
|
4pdjA |
Neutron crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+ |
|
43
|
157
|
4q6aA |
Staphylococcus aureus v31l, f98y mutant dihydrofolate reductase complexed with nadph |
|
43
|
159
|
4p68A |
Electrostatics of active site microenvironments for e. coli dhfr |
|
40
|
157
|
4q67A |
Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph |
|
162
|
519
|
4q0dA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump, methotrexate and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
41
|
159
|
4p66A |
Electrostatics of active site microenvironments of e. coli dhfr |
|
157
|
519
|
4q0eA |
Crystal structure of ts-dhfr from cryptosporidium hominis in complex with nadph, fdump and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-l-glutamic acid. |
|
44
|
159
|
4nx6A |
Single room temperature model of dhfr |
|
38
|
159
|
4osgA |
Klebsiella pneumoniae complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxyl-5-(pyridine-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1006) |
|
44
|
159
|
4nx7A |
Single cryogenic temperature model of dhfr |
|
45
|
165
|
4or7A |
Klebsiella pneumoniae dihydrofolate reductase complexed with nadph and 6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine |
|
53
|
186
|
4m6lA |
Crystal structure of human dihydrofolate reductase (dhfr) bound to nadp+ and 5,10-dideazatetrahydrofolic acid |
|
49
|
168
|
4m7vA |
Dihydrofolate reductase from enterococcus faecalis complexed with nadp(h)and rab-propyl |
|
54
|
186
|
4m6kA |
Crystal structure of human dihydrofolate reductase (dhfr) bound to nadp+ and folate |
|
49
|
170
|
4m7uA |
Dihydrofolate reductase from enterococcus faecalis complexed with nadp(h) |
