|
272
|
947
|
3l08A |
Structure of pi3k gamma with a potent inhibitor: gsk2126458 |
|
253
|
949
|
3l13A |
Crystal structures of pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors |
|
261
|
949
|
3l17A |
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors for the treatment of cancer |
|
260
|
949
|
3l16A |
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-pi3-kinase and dual pan-pi3-kinase/mtor inhibitors for the treatment of cancer |
|
271
|
952
|
3l54A |
Structure of pi3k gamma with inhibitor |
|
237
|
950
|
3ibeA |
Crystal structure of a pyrazolopyrimidine inhibitor bound to pi3 kinase gamma |
|
306
|
1084
|
3hhmA |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha and the drug wortmannin |
|
281
|
1089
|
3hizA |
Crystal structure of p110alpha h1047r mutant in complex with nish2 of p85alpha |
|
265
|
949
|
3eneA |
Complex of pi3k gamma with an inhibitor |
|
254
|
952
|
3dpdA |
Achieving multi-isoform pi3k inhibition in a series of substituted 3,4-dihydro-2h-benzo[1,4]oxazines |
|
259
|
949
|
3dbsA |
Structure of pi3k gamma in complex with gdc0941 |
|
268
|
945
|
3cstA |
Crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor e5e2 |
|
271
|
945
|
3csfA |
Crystal structure of pi3k p110gamma catalytical domain in complex with organoruthenium inhibitor dw2 |
|
267
|
950
|
3apcA |
Crystal structure of human pi3k-gamma in complex with ch5132799 |
|
264
|
950
|
3apdA |
Crystal structure of human pi3k-gamma in complex with ch5108134 |
|
241
|
949
|
3apfA |
Crystal structure of human pi3k-gamma in complex with ch5039699 |
|
251
|
1045
|
2y3aA |
Crystal structure of p110beta in complex with icsh2 of p85beta and the drug gdc-0941 |
|
275
|
919
|
2x38A |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with ic87114. |
|
286
|
919
|
2wxgA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with sw13. |
|
268
|
919
|
2wxnA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with dl07. |
|
271
|
919
|
2wxjA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with ink654. |
|
276
|
919
|
2wxpA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with gdc-0941. |
|
268
|
919
|
2wxqA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with as15. |
|
277
|
919
|
2wxlA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with zstk474. |
|
283
|
919
|
2wxhA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with sw14. |
|
276
|
919
|
2wxiA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with sw30. |
|
190
|
658
|
2x6hA |
The crystal structure of the drosophila class iii pi3-kinase vps34 |
|
279
|
919
|
2wxfA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with pik-39. |
|
279
|
919
|
2wxoA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with as5. |
|
194
|
658
|
2x6jA |
The crystal structure of the drosophila class iii pi3-kinase vps34 in complex with pik-93 |
|
266
|
919
|
2wxrA |
The crystal structure of the murine class ia pi 3-kinase p110delta. |
|
182
|
658
|
2x6fA |
The crystal structure of the drosophila class iii pi3-kinase vps34 in complex with 3-methyladenine |
|
278
|
919
|
2wxmA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with dl06. |
|
183
|
658
|
2x6iA |
The crystal structure of the drosophila class iii pi3-kinase vps34 in complex with pik-90 |
|
271
|
919
|
2wxkA |
The crystal structure of the murine class ia pi 3-kinase p110delta in complex with ink666. |
|
181
|
658
|
2x6kA |
The crystal structure of the drosophila class iii pi3-kinase vps34 in complex with pi-103 |
|
272
|
949
|
2v4lA |
Complex of human phosphoinositide 3-kinase catalytic subunit gamma (p110 gamma) with pik-284 |
|
262
|
1077
|
2rd0A |
Structure of a human p110alpha/p85alpha complex |
|
22
|
90
|
2v1yA |
Structure of a phosphoinositide 3-kinase alpha adaptor-binding domain (abd) in a complex with the ish2 domain from p85 alpha |
|
18
|
158
|
2enqA |
Solution structure of the c2 domain from human pi3-kinase p110 subunit alpha |
|
267
|
949
|
2chxA |
A pharmacological map of the pi3-k family defines a role for p110alpha in signaling: the structure of complex of phosphoinositide 3-kinase gamma with inhibitor pik-90 |
|
262
|
949
|
2chzA |
A pharmacological map of the pi3-k family defines a role for p110alpha in signaling: the structure of complex of phosphoinositide 3-kinase gamma with inhibitor pik-93 |
|
260
|
949
|
2chwA |
A pharmacological map of the pi3-k family defines a role for p110 alpha in signaling: the structure of complex of phosphoinositide 3- kinase gamma with inhibitor pik-39 |
|
252
|
949
|
2a5uA |
Crystal structure of human pi3kgamma complexed with as605240 |
|
222
|
944
|
2a4zA |
Crystal structure of human pi3kgamma complexed with as604850 |
|
247
|
941
|
1he8A |
Ras g12v - pi 3-kinase gamma complex |
|
259
|
952
|
1e7vA |
Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine |
|
274
|
952
|
1e8wA |
Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine |
|
267
|
951
|
1e8xA |
Structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling |
|
260
|
952
|
1e90A |
Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine |