|
125
|
313
|
5sjdA |
Crystal structure of human phosphodiesterase 10 in complex with 1-[2-(3,5-dimethylpyrazol-1-yl)ethyl]-3-(2-phenylpyrazol-3-yl)urea |
|
121
|
317
|
5sf2A |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-n-(3-oxo-1,2-dihydroisoindol-5-yl)-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide |
|
123
|
313
|
5sjtA |
Crystal structure of human phosphodiesterase 10 in complex with 4-n,4-n,2-trimethyl-3-n-(2-phenylimidazo[1,2-a]pyridin-7-yl)pyrazole-3,4-dicarboxamide |
|
127
|
314
|
5siqA |
Crystal structure of human phosphodiesterase 10 in complex with 2-ethyl-3-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]quinoxaline |
|
125
|
313
|
5sfaA |
Crystal structure of human phosphodiesterase 10 in complex with 6-cyclopropyl-3-[(1-methyl-4-phenylimidazol-2-yl)methoxy]-n-(oxolan-3-yl)pyrazine-2-carboxamide |
|
123
|
313
|
5sj5A |
Crystal structure of human phosphodiesterase 10 in complex with 6-chloroquinoxalin-2-amine |
|
123
|
313
|
5shuA |
Crystal structure of human phosphodiesterase 10 in complex with 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-3,5,6,7-tetrahydropyrrolo[3,2-f]benzimidazole |
|
124
|
313
|
5skaA |
Crystal structure of human phosphodiesterase 10 in complex with 7-[(4-ethoxy-5-methylpyridin-2-yl)methylsulfanyl]-6h-imidazo[4,5-g][1,3]benzothiazole |
|
121
|
313
|
5seiA |
Crystal structure of human phosphodiesterase 10 in complex with 6-chloro-2-[(e)-2-(2-methyl-5-pyrrolidin-1-yl-1,2,4-triazol-3-yl)ethenyl]-[1,2,4]triazolo[1,5-a]pyridine |
|
124
|
313
|
5sfzA |
Crystal structure of human phosphodiesterase 10 in complex with 1-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]-3-(2-phenylpyrazol-3-yl)urea |
|
126
|
316
|
5sg4A |
Crystal structure of human phosphodiesterase 10 in complex with 3-n-[2-(3-chlorophenyl)-1h-benzimidazol-5-yl]-2-methylpyrazole-3,4-dicarboxamide |
|
125
|
313
|
5sj7A |
Crystal structure of human phosphodiesterase 10 in complex with 7-[(5-methyl-4-propan-2-yloxypyridin-2-yl)methylsulfanyl]-6h-imidazo[4,5-g][1,3]benzothiazole |
|
114
|
434
|
7eg1A |
Cryo-em structure of dnmdp-induced pde3a-slfn12 complex |
|
112
|
434
|
7eg4A |
Cryo-em structure of nauclefine-induced pde3a-slfn12 complex |
|
108
|
434
|
7eg0A |
Cryo-em structure of anagrelide-induced pde3a-slfn12 complex |
|
134
|
432
|
7lrdB |
Cryo-em of the slfn12-pde3a complex: consensus subset model |
|
134
|
432
|
7lrcB |
Cryo-em of the slfn12-pde3a complex: pde3a body refinement |
|
140
|
376
|
7l27A |
Crystal structure of the catalytic domain of human pde3a |
|
147
|
377
|
7kweA |
Crystal structure of the catalytic domain of human pde3a bound to dnmdp |
|
141
|
377
|
7l28A |
Crystal structure of the catalytic domain of human pde3a bound to trequinsin |
|
142
|
377
|
7l29A |
Crystal structure of the catalytic domain of human pde3a bound to amp |
|
137
|
339
|
6zqzA |
[1,2,4]triazolo[1,5-a]pyrimidine phosphodiesterase 2 inhibitors |
|
123
|
312
|
7bpiA |
The crystal structue of pde10a complexed with 14 |
|
127
|
326
|
6zndA |
[1,2,4]triazolo[1,5-a]pyrimidine phosphodiesterase 2 inhibitors |
|
142
|
354
|
6blfA |
Pde2 complexed with 2-[6-fluoro-8-methylsulfonyl-9-[(1r)-1-[4-(trifluoromethyl)phenyl]ethyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid |
|
130
|
328
|
6msaA |
Novel, potent, selective and brain penetrant phosphodiesterase 10a inhibitors |
|
134
|
322
|
6mscA |
Novel, potent, selective and brain penetrant phosphodiesterase 10a inhibitors |
|
120
|
323
|
5znlA |
Crystal structure of pde10a catalytic domain complexed with lhb-6 |
|
113
|
324
|
6ijiA |
Crystal structure of pde10 in complex with inhibitor 2b |
|
122
|
322
|
6ijhA |
Crystal structure of pde10 in complex with inhibitor af-399/14387019 |
|
115
|
312
|
5k9rA |
Pde10a with imidazopyrazine inhibitor |
|
130
|
313
|
5i2rA |
Human pde10a in complex with 3-(2-phenylpyrazol-3-yl)-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one |
|
140
|
342
|
6ezfA |
Pde2 in complex with molecule 5 |
|
135
|
352
|
6cycA |
Pde2 in complex with compound 5 |
|
132
|
352
|
6cydA |
Pde2 in complex with compound 7 |
|
134
|
352
|
6cybA |
Pde2 in complex with compound 7 |
|
135
|
342
|
6c7dA |
Crystal structure of human phosphodiesterase 2a with n-(1-adamantyl)-1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
137
|
342
|
6c7eA |
Crystal structure of human phosphodiesterase 2a with 1-(2-chlorophenyl)-n,4-dimethyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
140
|
339
|
6c7fA |
Crystal structure of human phosphodiesterase 2a with 1-(2-chloro-5-isobutoxy-phenyl)-n,4-dimethyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
136
|
342
|
6c7jA |
Crystal structure of human phosphodiesterase 2a with 1-(5-tert-butoxy-2-chloro-phenyl)-n-isobutyl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
136
|
342
|
6c7iA |
Crystal structure of human phosphodiesterase 2a with 1-(2-chloro-5-methoxy-phenyl)-n-isobutyl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
133
|
341
|
6c7gA |
Crystal structure of human phosphodiesterase 2a with n-(1-adamantyl)-1-(2-chloro-5-isobutoxy-phenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide |
|
134
|
352
|
6b97A |
Crystal structure of pde2 in complex with complex 9 |
|
130
|
353
|
6b98A |
Pde2 in complex with compound 1 |
|
136
|
352
|
6b96A |
Crystal structure of pde2 in complex with compound 16 |
|
132
|
340
|
5xkmA |
Crystal structure of human phosphodiesterase 2a in complex with 6-methyl-n-(1-(4-(trifluoromethoxy)phenyl)propyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide |
|
125
|
322
|
5xuiA |
Crystal structure of pde10a in complex with 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)et hyl]pyrazolo[1,5-a]pyrimidin-7-ol |
|
121
|
322
|
5xujA |
Crystal structure of pde10a in complex with 7-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine |
|
135
|
353
|
5w6eA |
Pde1b complexed with compound 3s |
|
130
|
338
|
5u7iA |
Pde2 catalytic domain complexed with inhibitors |
