|
103
|
387
|
4frjA |
Crystal structure of bace1 in complex with aminooxazoline xanthene 9l |
|
105
|
390
|
4fs4A |
Structure of bace bound to (s)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1h)-iminium |
|
98
|
387
|
4frkA |
Crystal structure of bace1 in complex with aminooxazoline xanthene 11a |
|
106
|
389
|
4frsA |
Structure of bace in complex with (s)-4-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1h)-iminium |
|
103
|
400
|
4fm7A |
Crystal structure of bace with compound 14g |
|
97
|
389
|
4fcoA |
Crystal structure of bace1 with its inhibitor |
|
102
|
400
|
4fm8A |
Crystal structure of bace with compound 12a |
|
97
|
386
|
3r2fA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with bms-693391 aka (2s)-2-((3r)-3-acetamido-3-isobutyl-2-oxo-1-pyrrolidinyl)-n-((1s,2r)-1-(3,5-difluorobenzyl)-2-hydroxy-2-((2r,4r)-4-propoxy-2-pyrrolidinyl)ethyl)-4-phenylbutanamide |
|
98
|
389
|
4fgxA |
Crystal structure of bace1 with novel inhibitor |
|
93
|
392
|
3r1gB |
Structure basis of allosteric inhibition of bace1 by an exosite-binding antibody |
|
97
|
389
|
3qi1A |
Design and synthesis of hydroxyethylamine (hea) bace-1 inhibitors: prime side chromane-containing inhibitors |
|
99
|
388
|
3qbhA |
Structure based design, synthesis and sar of cyclic hydroxyethylamine (hea) bace-1 inhibitors |
|
98
|
388
|
3pi5A |
Crystal structure of human beta secretase in complex with bfg356 |
|
101
|
387
|
3ohfA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with bms-655295 aka n~3~-((1s,2r)-1- benzyl-2-hydroxy-3-((3-methoxybenzyl)amino)propyl)-n~1~, n~1~-dibutyl-1h-indole-1,3-dicarboxamide |
|
102
|
386
|
3oozA |
Bace1 in complex with the aminohydantoin compound 102 |
|
104
|
387
|
3ohhA |
Crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with bms-681889 aka n~1~-butyl-5-cyano- n~3~-((1s,2r)-1-(3,5-difluorobenzyl)-2-hydroxy-3-((3- methoxybenzyl)amino)propyl)-n~1~-methyl-1h-indole-1,3- dicarboxamide |
|
103
|
388
|
3nshA |
Bace-1 in complex with eln475957 |
|
90
|
389
|
3n4lA |
Bace-1 in complex with eln380842 |
|
93
|
387
|
3mskA |
Fragment based discovery and optimisation of bace-1 inhibitors |
|
103
|
389
|
3msjA |
Structure of bace (beta secretase) in complex with inhibitor |
|
91
|
387
|
3mslA |
Fragment based discovery and optimisation of bace-1 inhibitors |
|
108
|
390
|
3lpjA |
Structure of bace bound to sch743641 |
|
100
|
388
|
3lhgA |
Bace1 in complex with the aminohydantoin compound 4g |
|
107
|
390
|
3lpiA |
Structure of bace bound to sch745132 |
|
105
|
390
|
3lnkA |
Structure of bace bound to sch743813 |
|
106
|
390
|
3lpkA |
Structure of bace bound to sch747123 |
|
89
|
387
|
3kyrA |
Bace-1 in complex with a norstatine type inhibitor |
|
102
|
390
|
3l5cA |
Structure of bace bound to sch723871 |
|
98
|
387
|
3l3aA |
Bace-1 with the aminopyridine compound 32 |
|
105
|
390
|
3l5fA |
Structure of bace bound to sch736201 |
|
100
|
386
|
3l38A |
Bace1 in complex with the aminopyridine compound 44 |
|
103
|
390
|
3l5bA |
Structure of bace bound to sch713601 |
|
103
|
390
|
3l5dA |
Structure of bace bound to sch723873 |
|
104
|
390
|
3l59A |
Structure of bace bound to sch710413 |
|
107
|
390
|
3l5eA |
Structure of bace bound to sch736062 |
|
104
|
395
|
3l58A |
Structure of bace bound to sch589432 |
|
104
|
395
|
3kmyA |
Structure of bace bound to sch12472 |
|
104
|
395
|
3kmxA |
Structure of bace bound to sch346572 |
|
104
|
390
|
3kn0A |
Structure of bace bound to sch708236 |
|
92
|
388
|
3k5dA |
Crystal structure of bace-1 in complex with ahm178 |
|
97
|
388
|
3k5cA |
Human bace-1 complex with nb-216 |
|
98
|
388
|
3k5gA |
Human bace-1 complex with bjc060 |
|
93
|
388
|
3k5fA |
Human bace-1 complex with ayh011 |
|
103
|
387
|
3in4A |
Bace1 with compound 38 |
|
103
|
387
|
3in3A |
Bace1 with compound 30 |
|
103
|
389
|
3infA |
Bace1 with the aminohydantoin compound 37 |
|
100
|
389
|
3inhA |
Bace1 with the aminohydantoin compound r-58 |
|
101
|
389
|
3iviA |
Design and synthesis of potent bace-1 inhibitors with cellular activity: structure-activity relationship of p1 substituents |
|
96
|
389
|
3indA |
Bace1 with the aminohydantoin compound 29 |
|
105
|
389
|
3ivhA |
Design and synthesis of potent bace-1 inhibitors with cellular activity: structure-activity relationship of p1 substituents |
