|
154
|
554
|
5vqxA |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacetamide (jlj686), a non-nucleoside inhibitor |
|
158
|
553
|
5vqsA |
Crystal structure of hiv-1 reverse transcriptase in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)acrylamide (jlj685), a non-nucleoside inhibitor |
|
113
|
424
|
5vqzB |
Crystal structure of hiv-1 reverse transcriptase (k103n, y181c) variant in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacetamide (jlj686), a non-nucleoside inhibitor |
|
113
|
424
|
5vqxB |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with 2-chloro-n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacetamide (jlj686), a non-nucleoside inhibitor |
|
109
|
424
|
5vqrB |
Crystal structure of hiv-1 reverse transcriptase in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacrylamide (jlj684), a non-nucleoside inhibitor |
|
111
|
424
|
5vqvB |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-n-methylacrylamide (jlj684), a non-nucleoside inhibitor |
|
113
|
424
|
5vquB |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-2-fluoro-n-methylacetamide (jlj683), a non-nucleoside inhibitor |
|
108
|
424
|
5vqwB |
Crystal structure of hiv-1 reverse transcriptase (y181c) variant in complex with n-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)acrylamide (jlj685), a non-nucleoside inhibitor |
|
161
|
554
|
5hbmA |
Crystal structure of a dihydroxycoumarin rnase h active-site inhibitor in complex with hiv-1 reverse transcriptase |
|
40
|
133
|
4qagA |
Structure of a dihydroxycoumarin active-site inhibitor in complex with the rnase h domain of hiv-1 reverse transcriptase |
|
108
|
425
|
4ncgB |
Discovery of doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant hiv viruses |
|
165
|
556
|
4ncgA |
Discovery of doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant hiv viruses |
|
160
|
556
|
4ig0A |
Hiv-1 reverse transcriptase with bound fragment at the 507 site |
|
150
|
556
|
4iclA |
Hiv-1 reverse transcriptase with bound fragment at the incoming dntp binding site |
|
167
|
556
|
4ig3A |
Hiv-1 reverse transcriptase with bound fragment near knuckles site |
|
125
|
424
|
4ig3B |
Hiv-1 reverse transcriptase with bound fragment near knuckles site |
|
114
|
424
|
4iclB |
Hiv-1 reverse transcriptase with bound fragment at the incoming dntp binding site |
|
164
|
556
|
4id5A |
Hiv-1 reverse transcriptase with bound fragment at the rnase h primer grip site |
|
122
|
424
|
4id5B |
Hiv-1 reverse transcriptase with bound fragment at the rnase h primer grip site |
|
116
|
424
|
4ig0B |
Hiv-1 reverse transcriptase with bound fragment at the 507 site |
|
116
|
424
|
4ifyB |
Hiv-1 reverse transcriptase with bound fragment at the knuckles site |
|
114
|
424
|
4idkB |
Hiv-1 reverse transcriptase with bound fragment at the 428 site |
|
161
|
556
|
4idkA |
Hiv-1 reverse transcriptase with bound fragment at the 428 site |
|
165
|
556
|
4ifyA |
Hiv-1 reverse transcriptase with bound fragment at the knuckles site |
|
157
|
556
|
4g1qA |
Crystal structure of hiv-1 reverse transcriptase (rt) in complex with rilpivirine (tmc278, edurant), a non-nucleoside rt-inhibiting drug |
|
117
|
424
|
4g1qB |
Crystal structure of hiv-1 reverse transcriptase (rt) in complex with rilpivirine (tmc278, edurant), a non-nucleoside rt-inhibiting drug |
|
101
|
423
|
3qlhB |
Hiv-1 reverse transcriptase in complex with manicol at the rnase h active site and tmc278 (rilpivirine) at the nnrti binding pocket |
|
144
|
555
|
3qlhA |
Hiv-1 reverse transcriptase in complex with manicol at the rnase h active site and tmc278 (rilpivirine) at the nnrti binding pocket |
|
155
|
557
|
3nbpA |
Hiv-1 reverse transcriptase with aminopyrimidine inhibitor 2 |
|
114
|
424
|
3nbpB |
Hiv-1 reverse transcriptase with aminopyrimidine inhibitor 2 |
|
151
|
557
|
3m8qA |
Hiv-1 rt with aminopyrimidine nnrti |
|
162
|
555
|
3m8pA |
Hiv-1 rt with nnrti tmc-125 |
|
112
|
424
|
3m8qB |
Hiv-1 rt with aminopyrimidine nnrti |
|
110
|
424
|
3m8pB |
Hiv-1 rt with nnrti tmc-125 |
|
110
|
423
|
3lp0B |
Hiv-1 reverse transcriptase with inhibitor |
|
152
|
558
|
3lp0A |
Hiv-1 reverse transcriptase with inhibitor |
|
102
|
423
|
3lp2B |
Hiv-1 reverse transcriptase with inhibitor |
|
106
|
423
|
3lp1B |
Hiv-1 reverse transcriptase with inhibitor |
|
154
|
558
|
3lp1A |
Hiv-1 reverse transcriptase with inhibitor |
|
153
|
558
|
3lp2A |
Hiv-1 reverse transcriptase with inhibitor |
|
131
|
551
|
3kliA |
Crystal structure of unliganded azt-resistant hiv-1 reverse transcriptase |
|
103
|
427
|
3kliB |
Crystal structure of unliganded azt-resistant hiv-1 reverse transcriptase |
|
141
|
556
|
3isnC |
Crystal structure of hiv-1 rt bound to a 6-vinylpyrimidine inhibitor |
|
134
|
554
|
3is9A |
Crystal structure of the hiv-1 reverse transcriptase (rt) in complex with the alkenyldiarylmethane (adam) non-nucleoside rt inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate). |
|
129
|
555
|
3irxA |
Crystal structure of hiv-1 reverse transcriptase (rt) in complex with the non-nucleoside rt inhibitor (e)-s-methyl 5-(1-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate. |
|
109
|
427
|
3isnD |
Crystal structure of hiv-1 rt bound to a 6-vinylpyrimidine inhibitor |
|
98
|
427
|
3ithB |
Crystal structure of the hiv-1 reverse transcriptase bound to a 6-vinylpyrimidine inhibitor |
|
102
|
428
|
3irxB |
Crystal structure of hiv-1 reverse transcriptase (rt) in complex with the non-nucleoside rt inhibitor (e)-s-methyl 5-(1-(3,7-dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate. |
|
103
|
428
|
3is9B |
Crystal structure of the hiv-1 reverse transcriptase (rt) in complex with the alkenyldiarylmethane (adam) non-nucleoside rt inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate). |
|
136
|
556
|
3ithA |
Crystal structure of the hiv-1 reverse transcriptase bound to a 6-vinylpyrimidine inhibitor |