|
139
|
389
|
6e41A |
Crystal structure of human indoleamine 2,3-dioxygenase 1 (ido1) in complex with ferric heme and an epacadostat analog |
|
130
|
389
|
6dpqA |
Mapping the binding trajectory of a suicide inhibitor in human indoleamine 2,3-dioxygenase 1 |
|
113
|
390
|
6dprA |
Mapping the binding trajectory of a suicide inhibitor in human indoleamine 2,3-dioxygenase 1 |
|
137
|
389
|
6e46A |
Crystal structure of human indoleamine 2,3-dioxygenase 1 (ido1) in complex with ferrous heme and tryptophan |
|
131
|
389
|
6e40A |
Crystal structure of the indoleamine 2,3-dioxygenase 1 (ido1) in complexed with ferric heme and epacadostat |
|
140
|
387
|
6e43A |
Crystal structure of human indoleamine 2,3-dioxygenase 1 (ido1) in complex with a bms-978587 analog |
|
141
|
382
|
6e42A |
Crystal structure of human indoleamine 2,3-dioxygenase 1 (ido1) in complex with ferric heme and 4-chlorophenyl imidazole |
|
217
|
658
|
6nquA |
Human lsd1 in complex with gsk2879552 |
|
127
|
418
|
6ngnA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
133
|
421
|
6ngeA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
|
127
|
418
|
6ngqA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
131
|
418
|
6ngsA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
|
131
|
418
|
6ngkA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine |
|
123
|
413
|
6nh6A |
Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine |
|
128
|
413
|
6nh5A |
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
128
|
413
|
6nh7A |
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine |
|
129
|
418
|
6nhdA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
129
|
413
|
6nh8A |
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine |
|
136
|
418
|
6ngvA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine |
|
129
|
418
|
6ngzA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
120
|
413
|
6nh4A |
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
135
|
418
|
6nglA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (r)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
131
|
418
|
6ngwA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine |
|
122
|
413
|
6nh3A |
Structure of human endothelial nitric oxide synthase heme domain in complex with (s)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
127
|
418
|
6ngyA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (r)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
113
|
413
|
6nh1A |
Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
|
127
|
413
|
6nhfA |
Structure of human endothelial nitric oxide synthase heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
133
|
421
|
6nhbA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(5-(2-((2s,4r)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
|
132
|
418
|
6nh0A |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
131
|
421
|
6nghA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
127
|
418
|
6ngjA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
|
135
|
421
|
6ngdA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine |
|
132
|
421
|
6ngiA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
134
|
421
|
6ngfA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (r)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
134
|
421
|
6ng7A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
132
|
418
|
6ngtA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine |
|
129
|
418
|
6nguA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine |
|
122
|
413
|
6nh2A |
Structure of human endothelial nitric oxide synthase heme domain in complex with (r)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
129
|
418
|
6ngxA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
|
126
|
418
|
6ngrA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2r,4s)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
129
|
418
|
6ngmA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (r)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
128
|
418
|
6ngpA |
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
133
|
421
|
6nhcA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (s)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
130
|
421
|
6ng1A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine |
|
135
|
421
|
6ngcA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine |
|
134
|
421
|
6ng8A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine |
|
133
|
421
|
6ng2A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine |
|
135
|
421
|
6ng6A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (s)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
131
|
421
|
6ng5A |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with (r)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine |
|
133
|
421
|
6ngbA |
Structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine |
